A61L2101/44

METHOD AND APPARATUS FOR INACTIVATING PATHOGENS IN UNITS OF WHOLE BLOOD USING SUPERPARAMAGNETIC NANOPARTICLES COATED WITH CHEMILUMINESCENCE REAGENTS AND BROAD-SPECTRUM ANTI-VIRAL THERAPEUTICS
20240335575 · 2024-10-10 · ·

A method and apparatus for reducing or inactivating pathogens in units of whole blood. A plurality of superparamagnetic nanoparticles (SPN) is coated with a mixture of chemiluminescence light-generating compounds and photodynamic broad-spectrum anti-viral compounds, and the mixture in introduced into a bag of whole blood. A rapidly-changing electromagnetic field is applied to the bag to cause uniform distribution of the nanoparticles within the whole blood throughout all regions of the blood bag, including the opaque interior of the bag. The blood is processed for a predetermined processing time period, during which the chemiluminescence light activates the broad-spectrum antiviral capacity of the photodynamic compounds to achieve reduction or inactivation of pathogens throughout the blood bag. After the processing time is elapsed, the nanoparticles are removed from the processed blood by a magnetic field. The processed blood may be washed by conventional means, to remove residual reagents, and transferred into a new, sterile blood bag.

ANTIPATHOGENIC NANOSTRUCTURES
20240341310 · 2024-10-17 ·

Methods include disposing a layer of a solution or emulsion having a nanostructure on a surface. The surface further includes a SARS-CoV-2 virus disposed thereon. The nanostructure includes a compound or salt thereof. The compound includes one or more styrene units, one or more N-alkylacrylamide units, and a moiety represented by the formula:

##STR00001##

where R.sup.1 is alkyl. The compound includes a moiety represented by the formula:

##STR00002##

where R.sup.1 is alkyl and R.sup.2 and R.sup.3 are independently hydrogen or alkyl. The compound includes a plurality of N,N-(dialkylamino)(divalent alkyl) alkylacrylate units. One or more of the N,N-(dialkylamino)(divalent alkyl)alkylacrylate units has an unsubstituted nitrogen. One or more of the N,N-(dialkylamino)(divalent alkyl)alkylacrylate units is substituted with a C.sub.1-C.sub.16 alkyl moiety, and one or more of the N,N-(dialkylamino)(divalent alkyl) alkylacrylate units is substituted with a moiety selected from the group consisting of guanidine, polygalactose, coumarin, and combination(s) thereof.

NASAL SWAB APPARATUS AND METHOD FOR APPLYING A CLEANING SOLUTION
20240342326 · 2024-10-17 ·

A nasal swab kit for cleaning and sanitizing human nose nasal vestibules includes a pair of nasal swab devices, each of the devices having a body from which two spaced apart prongs extend, and each of the prongs having a free end to which a swab is attached. The swabs of a first of the devices are saturated with at least one cleaning ingredient selected from sterile water, glycerin, sodium chloride, sodium benzoate, PEG 60 hydrogenated castor oil, cocamidopropyl betaine and lavender oil. The swabs of a second of the devices are saturated with a sanitizing ingredient such as isopropyl alcohol or mupirocin. The kit includes a first packet inside which the first device is sealed and a second packet inside which the second device is sealed wherein the packets are conjoined at a perforated seam.

METHOD FOR THE PREPARATION OF SURFACES, PARTICULARLY OF CARDIAC PROSTHESIS
20240342330 · 2024-10-17 ·

A method for preventing both active and passive early degeneration of prosthesis to be contacted with biological fluid is provided.

LIGHT ACTIVATED CLEANING COMPOSITION

A light activated cleaning composition comprising a photosensitizer and a singlet oxygen quenching molecule.

MALODOR-COUNTERACTING COMPOUNDS, COMPOSITIONS, AND USES THEREOF

Provided herein are compounds, compositions, and methods for counteracting malodor and providing longevity and durability to fragrance ingredients. Also provided are consumer products including malodor-counteracting compounds or compositions.

APPARATUS AND METHOD FOR STERILIZING AND STORING DUAL MEMBRANE SENSOR COMPONENT

Sterilizable enzymatic sensors and sensor assemblies are provided, the enzymatic sensor including at least one enzymatic sensing membrane located at or near a distal tip of the enzymatic sensor. A sensor assembly may be packaged in a partially assembled state within a flexible package, at least a portion of which is permeable to ethylene oxide (ETO). The sensor assembly may also include a flexible tube which can be connected to the enzymatic sensor such that a distal section of the enzymatic sensor is positioned within an interior of the flexible tube, and a distal tube cap connected to a distal end of the flexible tube, the cap including an internal passage allowing passage of the distal tip of the enzymatic sensor therethrough, a plurality of filtered ports, and a gasket dimensioned to form a fluid-tight seal when a portion of the sensor is inserted through the gasket. The sensor assembly may also include a sealing membrane to occlude a distal end of the internal passage of the distal tube cap. Further assembly of the sensor assembly may be performed within the flexible package after ETO sterilization.

Antimicrobial filter media, preparation method thereof, and air cleaner comprising same

An antimicrobial filter media, which includes a non-woven fabric; and an antimicrobial agent bound to the nonwoven fabric by a binder, the antimicrobial agent including silver sodium zirconium hydrogenphosphate and thiabendazole, and the silver sodium zirconium hydrogenphosphate and the thiabendazole are employed at a weight ratio of 1:1.5 to 1.5:1, to an air cleaner including the same, and to a process for preparing the same. The antimicrobial filter media includes silver sodium zirconium hydrogenphosphate and thiabendazole, as an antimicrobial agent, at a specific weight ratio. As a result, it is possible to effectively filter harmful microorganisms to supply purified air, to have excellent antibacterial, antiviral, and antifungal properties at the same time, and to further enhance the durability and lifespan characteristics by virtue of excellent filter damage prevention effect.

Water-miscible functional fluid, undiluted stock of water-miscible functional fluid, sterilizer for water-miscible functional fluid, and method of sterilizing water-miscible function fluid

A water-miscible functional fluid includes: a neutral photosensitizer having an isoalloxazine skeleton; and an antioxidant, wherein the antioxidant is a radical scavenger or a peroxide decomposer.

CLEANING COMPOSITION
20250236819 · 2025-07-24 ·

The present invention relates to cleaning compositions comprising low levels of hydrogen peroxide and at least one acid selected from the group consisting of salicylic acid, furoic acid and formic acid. The compositions and methods of the invention are particularly suitable for use in household cleaning, for example in hard-surface cleaning or cleaning soft surfaces such as textiles and laundry.