The invention relates to a method and an automatic disinfection machine for the controlled disinfection of the skin of a patient comprising a treatment chamber for accommodating the body part with the skin to be disinfected; an electrically controllable disinfecting device for disinfecting the skin, a recording device for recording the disinfection of the skin in the form of disinfection data, a data processing control device for controlling the disinfecting device and the recording device. The control device is thereby designed to effect the disinfection of the skin by controlling the disinfecting device, record the disinfection of a skin section of the skin in the form of disinfection data by controlling the recording device.

A linear stem (3) guides a sliding door (11), which is dragged by a magnetic drive unit between an operating position (W), in which it covers and closes an access mouth (20) to an internal compartment (21) of a sterilizer (1), and an inoperative or opening (N), in which the door (11) moves to a position next to the access mouth (20), thus making it accessible from the outside.

The sliding door (11) is operated by movement members (5), comprising a linear module (50), adapted to house a transmission belt (52) stretched between two return wheels (53), one of which is driven by an electric gearmotor (54); a branch of the transmission belt (52) carries a slider (55) with a permanent magnet (56), facing a magnetic plate (6) fixed to the sliding door (11) which is dragged by the magnetic field generated by the cursor (55) in motion.

The invention relates to products by processes, product compositions, product formulations and product uses that are all related to reduced ultrapure water cluster sizes in an aqueous composition containing a non-H.sub.2O substance in the reduced size water clusters in order to improve bioavailability of the aqueous composition. The invention processes use higher flow rate of the blended aqueous composition from a jet openings of a nozzle inside the hollow cylinder to reduce sizes of the ultrapure water clusters in the blended aqueous composition of the non-H.sub.2O substance to less than 300 nanometers.

The invention relates to chemical and pharmaceutical industry, in particular to technologies of obtaining sterile drugs, drug substances and cosmetic products used in the form of solutions or emulsions, and comprising poloxamer. The thermal method for sterilizing aqueous poloxamer solutions is provided, the method including: dissolving a poloxamer in water for injection; performing the sterilizing filtration of the aqueous poloxamer solution simultaneously with filling sterile containers with the filtered poloxamer solution; sealing the containers containing the poloxamer solution; applying a thermal sterilization with steam under pressure to the containers containing the poloxamer solution, and cooling them, wherein the thermal sterilization of the containers containing the poloxamer solution with steam under pressure is performed under the pressure between 82.4 and 107.8 kPa.

Sanitizing surfaces comprising a sanitization device including a mobile body; and extending the sanitization device (102) laterally from the mobile body across a surface. A source of UV radiation (104) is mounted on the sanitization device. The sanitization device moves across the surface; exposing the surface to UV radiation produced by the source; directing a source of UV radiation to the surface at a predetermined dosage while the device moves over surface. Moving and locating the sanitization device can be inwardly and outwardly relative to the mobile body to extend at different angles being from a horizontal angle relative to the mobile body to a non-horizontal angle relative to the mobile body and to effect sanitization when so extended. The device is operable upwardly and downwardly across the surface while effecting the sanitation.

A sterilization unit for sterilizing a product can include a body having an internal volume for receiving the product to be sterilized, and comprising at least one opening through which product can be introduced and/or withdrawn from the internal volume; a gas inlet in fluid communication with the internal volume for introducing one or more of an inert gas and a sterilizing gas into the internal volume during sterilization; a screen disposed in the gas inlet through which the one or more of the inert gas and the sterilizing gas must pass before entering into the internal volume; and a pressure release valve. The body can be capable of being pressurized to a pressure of 10 atm or more.

A direct sodium removal (“DSR”) infusate regimen and methods of use are provided for removing sodium and reducing fluid overload in patients with severe renal dysfunction and/or heart failure, in which a patient has at least a first DSR session with a first DSR infusate having no or low sodium that is instilled into a patient's peritoneal cavity for a first dwell period to cause sodium and excess fluid to migrate to the patient's peritoneal cavity, and thereafter, the patient may undergo conventional dialysis to rebalance the patient's fluid and sodium levels.

A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.

A method for producing a collagen meniscus implant by obtaining a freshly excised non-human meniscus, rinsing it in an aqueous solution, drying the rinsed meniscus, shaping it to approximate in dimension an average-sized human meniscus, extracting non-collagenous material from the shaped meniscus, and sterilizing it, yielding a collagen meniscus implant containing at least 90% by weight of type I collagen, less than 0.5% by weight of glycosaminoglycan, and less than 600 ppm DNA. Also disclosed is a collagen meniscus implant prepared by the above method. Further provided is a biocompatible and bioresorbable porous implant for meniscus repair. The implant includes a three-dimensional network of collagen fibers oriented in a direction approximating the collagen fiber orientation of a human meniscus. The implant has a size and a contour substantially equivalent to a human meniscus, and has a chemical composition similar to the above-described collagen meniscus implant.

An instrument produces clean and/or sterile products or compounds. The instrument includes a housing defining a clean interior. The housing has an inlet and a first HEPA filter for filtering an inflow through the inlet to create filtered air. A plurality of UV-C lights irradiate the interior. A 3D printer is in the interior to produce clean products. Preferably, the interior is CGMP compliant. The instrument may also have micro spray nozzles for spraying a sterilizing agent within the interior. A pressure pump can create a pressure differential, positive or negative, within the housing. Typically, the housing has an outlet with a second HEPA filter for filtering an outflow through the outlet to create environmentally safe air. An air circulator can create a laminar air flow through the housing.