Patent classifications
A61L2202/22
CONTAINER FOR THE EX-VIVO TREATMENT OF BIOLOGICAL FLUIDS
The invention relates to a recipient (1) for ex-vivo treatment of biological liquids, which includes: a rigid body (2); a reservoir (3) provided inside the body (2), which is formed by a side wall (4), a rigid upper wall (5) and a rigid lower wall (6) and has an internal thickness defined by the separation between the upper wall (5) and the lower wall (6), at least one of the upper wall (5) or the lower wall (6) having a window area (7) configured to allow the passage of electromagnetic radiation from outside of the body (2) to the reservoir (3); two ports (8, 9) for liquids to gain access to the reservoir (3) from outside of the body (2); and closure means (10, 11) for the ports (8, 9), the closure means (10, 11) being configured to provide, jointly, the reservoir (3) with hermetic sealing against gases and liquids.
X-RAY IRRADIATOR FOR SINGLE BLOOD BAGS
The present invention relates to an X-ray irradiator for single blood bags, comprising: an X-ray irradiator main body provided with a chamber configured to safely hold a single blood bag therein and an X-ray tube configured to irradiate the chamber with X-rays; a loading part configured to load the blood bag; and a transfer part configured to transfer the blood bag between the loading part and the chamber to which X-rays are to be emitted. The X-ray irradiator for single blood bags according to the present invention can treat a single blood bag with X-rays, such that treatment optimized for a small amount of a blood bag can be performed, and a system configuration can be simplified by using an X-ray tube.
Method and apparatus for sterilizing and disinfecting air and surfaces and protecting a zone from external microbial contamination
This invention relates to a method, process and apparatus for disinfecting and sterilizing all types of surfaces contaminated with microorganisms and toxic substances to render both inactive. Furthermore, this invention relates to both a method and apparatus for disinfecting and/or sterilizing breathable air and then using this air to protect a confined space from external contamination. The apparatus consists of a new ultra-violet (NUV) source that is more effective than mercury based 254 nm light for destroying DNA of virus, bacteria, spores and cists. It is most effective in breaking chemical bonds in toxic gases and Biotoxins that are useful to terrorists. It is combined with other apparatus that remove particulates and byproducts sometimes produced by the NUV source and maintains positive pressure of the confined space so as to prevent the influx of air from outside the protected zone.
Anaerobic blood storage and pathogen inactivation method
A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced hemolysis. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles. Oxygen and pathogen reduced blood compositions comprising CPAD and riboflavin having reduced hemolysis. Oxygen and pathogen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles.
INACTIVATION OF HIGHLY RESISTANT INFECTIOUS MICROBES AND PROTEINS WITH UNBUFFERED HYPOHALOUS ACID COMPOSITIONS
Methods for true sterilization of an object, methods for inactivating an infectious protein, and methods for inactivating a microbial pathogen using a bufferless, electrolyzed, hypohalous acid composition.
MEDICAL ULTRAVIOLET-C REMOTE RESPIRATOR
An ultraviolet-C respirator mask that filters and destroys viruses by means of a HEPA type filter and a plurality of UVC LEDs projected on the filter. The filter element is worn on the garment of the user by means of an integral apparel clip and connected to the face mask through a breathing hose. This configuration allows easy replacement of the HEPA filter element and/or the facemask for considerations of hygiene. Filter element life is increased due to location further from contaminated field. Hygiene for the user is improved due to the collecting media being further from the user's face.
Lyophilization
Embodiments of methods, systems, and apparatuses for lyophilizing, storing, and transfusing materials are described. In embodiments, the materials may include whole blood or a component of whole blood such as plasma.
MULTIPLE LAMINAR FLOW-BASED PARTICLE AND CELLULAR SEPARATION WITH LASER STEERING
The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.
CRYOPRECIPITATE COMPOSITIONS AND METHODS OF PREPARATION THEREOF
Provided herein are compositions and kits including a pathogen-inactivated cryoprecipitate suitable for infusion into a subject at least 1 day after thawing. The methods are useful in the efficient preparation of cryoprecipitates with desirable characteristics, including pathogen-inactivated cryoprecipitates that are suitable for infusion into a subject at least 1 day after thawing.
ULTRAVIOLET LIGHT TREATMENT CHAMBER
An apparatus for the treatment of a liquid that includes a chamber having at least one inner surface, the chamber adapted for passage of a fluid therethrough. The chamber is at least 80 percent enclosed. The apparatus also includes an optional ultraviolet-transmissive tube disposed within the chamber and also adapted for the passage of the liquid therethrough. The apparatus further includes an ultraviolet lamp disposed within the chamber and, optionally, within the ultraviolet-transmissive tube. A reflective material is interposed between the chamber and the transmissive tube. The reflective material is adapted so as to reflect at least a portion of light emitted by the ultraviolet lamp, wherein the reflective material is at least 80 percent reflective.