A flexible hemostatic pad formed from a hemostatic powder, which may contain a hydrophilic polymer such as a cation ion exchange resin, compressed onto or into a velvet-like backing substrate is provided for the control of bleeding at a wound site.

Described herein is a multifunctional polymer-nanoparticle composition for use in wound care applications. Methods of manufacturing the described compositions are also disclosed herein.

In various embodiments, a tissue thickness compensator can comprise one or more capsules and/or pockets comprising at least one medicament therein. In at least one embodiment, staples can be fired through the tissue thickness compensator to rupture the capsules. In certain embodiments, a firing member, or knife, can be advanced through the tissue thickness compensator to rupture the capsules.

The invention relates to an implant (1) with antimicrobial activity, comprising an implant mixture (IM) which has a base granular material (2) formed from a raw material mixture of biocompatible polymers and/or a ceramic granular material, the implant mixture (IM) also comprising at least one type of metal (3) in particle form which is suitable for releasing ions, the metal particles (3) being present in the form of silver particles and/or copper particles. The metal particles (3) are distributed in the volume of the implant (1). The invention also relates to a method for producing an implant (1) of said type.

Disclosed are compositions comprising a copper complex useful in the reduction of inflammation in one or more tissues. Also disclosed are methods of utilizing the copper complexes for treating/preventing inflammation in one or more tissues, treating/enhancing wound healing, preventing/reducing DNA damage caused by radiation, and reducing free radical damage.

The present invention provides novel multi-functional (e.g., repelling biofilms, promoting formation of minerals, and having anti-infection properties) biocomposites and methods of use thereof. In various embodiments, the present invention also provides method for simultaneously treating biofilms, promoting mineralization, treating infection, or any combination thereof.

A method for reducing post-operative scar formation on a skin of a patient comprises applying a composition or material comprising copper, zinc and/or silver compounds to a postoperative wound under continuous peripheral pressure to the surgical incision and surrounding inflamed tissue, in order to reduce the inflammatory response, improve wound healing, reduce wounds complications and improve scar formation.

Gold implant having a cross-section in the range of 20-100, preferably in the range of 20-40 μm for use in therapy to prevent or reduce capsular contracture. Further, the invention relates to a method of producing a gold-coated implant.

The present disclosure relates to novel bone putty compositions comprising a silicate-containing preparation and bone and/or a bone surrogate material, and methods for making and using the same in healing damaged bone in a subject in need thereof. The present compositions may also promote healing of soft tissue contiguous with the treated damaged bone which is in contact with the present compositions. In some embodiments, the present compositions are stabilized, and contain silicate-containing particles having a mean diameter of from about 1 to about 20 nm. Such particles may impart unique healing characteristics to the composition, both with respect to the damaged bone and the surrounding soft tissue. The present compositions and methods may find particular utility in the oral cavity of the subject.

The main purpose of this technology is developing a collagen matrix or membrane with antimicrobial properties, comprising collagen from fetal amniotic membranes and metallic nanoparticles. Additionally, its manufacturing procedure is described.