Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.

A patch is provided. The patch comprises: a base layer; and an adhesive layer formed on a surface of the base layer, the adhesive layer has a wave pattern such that 95% or less of the area of the surface of the base layer is covered by the adhesive of the adhesive layer, wherein, the patch has an elongation of at least 120% in both machine direction and cross-machine direction.

The invention relates to a biodegradable, magnesium-containing bone screw for implanting into a patient body for use in medical applications, such as, orthopedic and craniofacial surgery. The bone screw has a tapered head, a threaded shaft and pointed tip. The composition of the bone screws provide for improved biodegradability and biocompatibility, and the features of the structure of the bone screws facilitates guidance and placement during implantation as well as reduces the potential for mechanical failures. Moreover, the bone screws are effective to provide targeted release of magnesium ions resulting in enhanced new bone formation.

An absorbent pad, such as a feminine hygiene article, according to the present disclosure comprises superabsorbent polymer particles (2). The superabsorbent polymer particles (2) are surface coated on an outer surface (3) with a coating agent (4), the coating agent (4) being water-soluble. The coated superabsorbent polymer particles (2) comprises an odour inhibiting substance (5) in powder form adhered to and/or mixed with the coating agent (3). The present disclosure also relates to methods of producing the absorbent pad (1).

Provided herein are formulations containing copper ions and methods of treating underlying infections and conditions caused by coronavirus, particularly COVID-19, and influenzas, particularly influenza A and/or influenza B using such formulations. Methods of treating the underlying viruses and their resultant conditions using topical copper ion treatments are provided. A topical treatment in its basic form comprises a biocompatible copper ion solution or suspension obtained by leaching of the copper ions from copper metal. The copper ion solution or suspension may be combined with various carriers to form the copper ion treatment including creams or solutions. Methods of making the copper ion solution or suspension from solid copper metal in a biocompatible solution are also provided.

The present disclosure relates in part to coating compositions comprising a bactericidal layer further comprising a bactericidal element and a columnar microstructure, which exerts bactericidal activity toward proximal and distal bacteria within an electrolyte solution (i.e. blood or other bodily fluid). The present disclosure further relates to coating compositions stably adhered to an electrode, which exerts bactericidal activity toward proximal and distal bacteria within an electrolyte solution upon application of an electric potential to the underlying electrode without a loss in efficiency of charge transfer.

The present invention discloses the device for a urinary catheter employing electromagnetic radiation and/or vibration transducer. The device comprises a clip-on (4) including a source of electromagnetic radiation (5) and/or a vibration transducer and a coupler (3) that allows electromagnetic radiation access from clip-on to the inside of the coupler. The combination of electromagnetic radiation and photo catalyst material may increase effectiveness for antimicrobial activity. The device aims at preventing the catheter-associated urinary tract infection caused by both intraluminal and extraluminal routes.

An absorbent sanitary article for absorbing a wet electrolytic or body fluid comprising, an outer material, which can comprise an absorbent low lint material, and a substrate material having a substrate surface and a reducing agent joined with the substrate material. A second substrate material can have a second substrate surface and an oxidizing agent joined with the second substrate material. Optionally at the second substrate surface, wherein the reducing agent and the oxidizing agent can be exposed to the wet electrolytic or body fluid during at least a portion of the time the absorbent sanitary article is in use.

The invention is directed to an ion plasma deposition (IPD) method adapted to coat polymer surfaces with highly adherent antimicrobial films. A controlled ion plasma deposition (IPD) process is used to coat a metal or polymer with a selected metal/metal oxide. Exposing the coated surface to ultraviolet light significantly improves the antimicrobial properties of the deposited coatings.

A non-pyrogenic preparation containing nanoparticles synthesized by magnetotactic bacteria for medical or cosmetic applications. The nanoparticles are constituted by a crystallized mineral central part including predominantly an iron oxide, as well as a surrounding coating without material from the magnetotactic bacteria.