A61M1/025

Closed disposable multiple sterile blood bag system for fractionating blood with the corresponding method

Disclosed is a multiple bag system for fractionating blood, the system including a fluid collecting bag including at least one outlet port; at least first and second sampling bags, each including at least one inlet port and at least one outlet port; and a fluid transfer unit to transfer fluid from the collecting bag to the sampling bags. The fluid transfer unit includes an acoustic sorter. Also disclosed is a method for fractionating blood into blood products.

Apparatus, systems and methods for storing, treating and/or processing blood and blood components

Apparatus, systems and methods are disclosed relating to certain aspects of blood processing, collecting or storing, including method and system for automated authentication, processing device with scanner, blood container with two dimensional barcode, blood collection containers, blood container label and related tracking method, integrated container system, and processing device with sterile connection device.

Thawing biological substances

Dry thawing systems and devices for thawing biological substances are provided herein. Methods for thawing biological substances are also provided.

Systems and methods for platelet concentration with a spinning membrane separator
10729829 · 2020-08-04 · ·

A method for automated processing of a blood product, the method comprising providing a reusable separation apparatus controlled by a microprocessing unit, said apparatus configurable with settings and configured to associate with a disposable circuit comprising a separator and in communication with a source blood product having a first concentration and first volume. The apparatus and disposable circuit are configured to flow the source blood product into an inlet of the separator and separate supernatant of the source blood product from a first outlet of the separator into a filtrate container. The apparatus and disposable circuit are also configured to separate platelets and remaining supernatant from a second outlet of the separator into a retentate container, wherein the platelets and remaining supernatant in the retentate container have a second concentration greater than the first concentration and second volume less than the first volume.

CELL PRESERVATION OR CULTURING ARRANGMENT

A biological cell preservation or culturing arrangement (20) comprises a chamber defining a fluid retaining space (30) for retaining in use a body of fluid (34) and a deformable membrane (36) in communication with the fluid retaining space, and being manipulable by an electroactive polymer actuator arrangement (38) to undergo a defined topology change to induce in the fluid a pattern of fluid flow by which fluid is exchanged between a sub-region (46) immediately proximal the deformable membrane and a sub-region (48) removed from the deformable membrane.

Smart bag used in sensing physiological and/or physical parameters of bags containing biological substance
10722623 · 2020-07-28 · ·

A cost-effective, single use bag or container is provided for storing biological substances that incorporates on its inner wall an electronic device that is configured to measure physiological and/or physical parameters of the enclosed biological substances, such as source history, identification, demographics, time stamping, temperature, pH, conductivity, glucose, O.sub.2, CO.sub.2 levels etc. The electronic device of the disclosed bag comprises a sensor configured to measure physiological and/or physical parameters of the biological substances enclosed within the bag, and a radio-frequency (RF) device communicably coupled to the sensor and configured to: (a) acquire from the sensor data associated with the measured parameters, (b) store the acquired sensor data in nonvolatile memory, and (c) communicate the stored data wirelessly to a RF reader.

PLATELET SEPARATOR, PLATELET RECOVERY DEVICE, PLATELET COLLECTION SYSTEM, AND PLATELET COLLECTION METHOD
20200222600 · 2020-07-16 · ·

A washed platelet having a sufficiently low blood plasma content rate is more securely and efficiently obtained.

A tertiary separator (42) includes a main body (58) which has a third chamber (52) and is formed as an accommodating portion (54a) accommodating a centrifuged platelet (104), an inlet (77c) which allows a platelet containing component (100) and a platelet added solution (102) to flow in, and an outlet (78a) which allows blood plasma, the platelet added solution (102), and the platelet (104) to flow out. A bottom portion (first bottom portion (60)) of at least a portion forming the accommodating portion (54a) in a wall portion included in the main body (58) is formed of a soft material.

BLOOD COMPONENT COLLECTION SYSTEM WITH PRESSURE DETECTION APPARATUS HAVING TWO LOAD DETECTORS AND METHOD
20200197582 · 2020-06-25 · ·

Provided is a blood component collection cassette, a blood component collection kit, a blood component collection system, and a flow path internal pressure detection method capable of accurately measuring a circuit internal pressure in negative pressure and positive pressure regions.

A flow path (42) formed in a cassette body (40) of a blood component collection cassette (28) has a first line (42a) through which blood flows when a blood component separation device is in operation, and a second line (42b) through which blood does not flow when the blood component separation device is in operation. A first line forming member (54) is provided with a first pressure-receiving portion (60) pressed by a first load detector (88) attached to the blood component separation device. A second line forming member (56) is provided with a second pressure-receiving portion (62) pressed by a second load detector (90) attached to the blood component separation device.

BIOLOGICAL COMPONENT COLLECTION KIT AND BLOOD COMPONENT COLLECTION SYSTEM
20200101404 · 2020-04-02 · ·

A third cassette (28) of a blood component collection kit (12) is equipped with a third cassette main body (29) in which a flow path (F) is formed together with having a filter accommodating unit (86), and a filter member (88) disposed in the filter accommodating unit (86). The flow path (F) includes a red blood cell line (f1) in which red blood cells flow, a preservation solution line (f2) in which a preservation solution flows, a confluence section (f3) in which the red blood cells and a preservation solution are made to merge together, a mixed liquid line (f4) through which a mixed liquid of the red blood cells and the preservation solution flows, and a filter chamber (f5) formed inside the filter accommodating unit (86).

Smart bag used in sensing physiological and/or physical parameters of bags containing biological substance
10576190 · 2020-03-03 · ·

The present technology discloses a cost-effective, single use bag or container for storing biological substances that incorporates on its inner wall an electronic device that is configured to measure physiological and/or physical parameters of the enclosed biological substances, such as source history, identification, demographics, time stamping, temperature, pH, conductivity, glucose, O.sub.2, CO.sub.2 levels etc. The electronic device of the disclosed bag comprises a sensor configured to measure physiological and/or physical parameters of the biological substances enclosed within the bag, and a radio-frequency (RF) device communicably coupled to the sensor and configured to: (a) acquire from the sensor data associated with the measured parameters, (b) store the acquired sensor data in nonvolatile memory, and (c) communicate the stored data wirelessly to a RF reader.