A biological component cassette includes a cassette main body having a flow path for the liquid in an interior of the cassette main body. The cassette main body is flexible and has a sheet-like shape. The biological component cassette includes a frame that is less flexible than the cassette main body. The frame includes an accommodation chamber in which the cassette main body is accommodated. A side portion of the frame forms at least part of the accommodation chamber. When the cassette main body is accommodated in the accommodation chamber, one surface of the cassette main body is covered by a bottom portion of the accommodation chamber, and another surface of the cassette main body is exposed to an external environment.

A blood donation system is provided that includes a plurality of collection containers (18, 20, 22, 24) interconnected by tubing (16, 28, 32, 34, 36, 38) and a leukocyte reduction filter (30). The system has a machine-readable identification code (48) associated therewith that is printed at repeated intervals on one of the tubings (16, 28, 32, 34, 36, 38), so as to define a plurality of discrete segments (44), each sized to contain a sample volume of blood or a blood product. After collection, heat seals (42) are formed on the tubing (16, 28, 32, 34, 36, 38) to capture in each segment (44) a volume of blood/blood product, such that a plurality of sample tubes are provided, each bearing the machine-readable identification code (48) and containing a volume of blood/blood product suitable for sample testing.

A fluid processing system includes a fluid processing device and a fluid flow circuit. The device includes a pump configured to convey a priming fluid through the circuit. The pressure in a conduit of the circuit is measured while the pump is operated at a particular rate. When the magnitude of the pressure is less than the magnitude of a predetermined pressure at the end of a time interval, the pump is operated at an increased rate. When the magnitude of the pressure is greater than the magnitude of the predetermined pressure at the end of the time interval, the pump is instead operated at a decreased rate. The magnitude of the pressure in the conduit is again compared to the magnitude of the predetermined pressure after the pump has operated at the increased or decreased rate for the time interval to determine how to next adjust the operational rate.

A device that can be used to store blood product and/or cellular culture that may or may not be under pressure. The device includes a chamber that can be hermetically sealed and a flexible secondary bag which can be placed in the chamber. The chamber is designed to receive at least one secondary bag that contains a conventional storage bag containing blood product and/or cellular culture. The storage conditions are created in the chamber and may or may not include 1) creating a pressure higher than atmospheric pressure, 2) creating a refrigerated temperature, and/or 3) providing agitation to the secondary bag. The secondary bag is filled with a gas system that is used to facilitate in the storage of the blood product and/or cellular culture. The secondary bag can be made of a material and/or include a coating or film that is impermeable to the gas system and to the gas inside the chamber. The higher-than-atmospheric pressure inside the chamber can be created by pumping an inexpensive gas, for example, air, into the chamber. The gas used to pressurize the chamber can be different from the gas system in the secondary bag.

Method for transfusion medicine to reduce adverse events in transfusion patient populations based on underlying patient physiology.

A medical bag system and a centrifugal separation system are equipped with a main bag in which blood is accommodated, a blood plasma bag in which blood plasma is accommodated, a chemical solution bag in which a red blood cell preservative solution is accommodated, and a transfer tube connecting the main bag, the blood plasma bag, and the chemical solution bag. The chemical solution bag includes a port side end portion having a connection port to which the transfer tube is connected, a suspended side end portion, which is an end portion opposite to the port side end portion, and which is formed with a suspension hole through which a suspension hook is inserted, and further including extension members that project out in a tongue shape from side portions of the suspension hole.

A medical contact shock freezer (10) adapted for fast freezing a plurality of individual bags (41-43, 51-53) containing a medical liquid, the individual bags being arranged side by side, adjacent to each other, in which the contact shock freezer comprises a pair of freezing plates comprising an upper freezing plate (21) and a lower freezing plate (22), at least one of the upper and lower freezing plates of the pair being moveable to define i) a loading position in which sufficient separation is provided between the freezing plates to load or unload the individual bags between the freezing plates and ii) a freezing position in which each individual bag is in contact with and is clamped between a contact surface of the upper freezing plate and a contact surface of the lower freezing plate; and in which, in its freezing position, the contact surface of the upper freezing plate is arranged at an angle of at least 2° to the horizontal.

The present disclosure provides apparatuses and systems for delivering a measureable absorbed-dose of a gaseous activating agent to a fluid including a biological liquid and/or cells. The apparatuses or systems include a gas-fluid contact device configured to controllably rotate or oscillate a control member having an interior surface in contact with the fluid and a control system configured to control rotation or oscillation of the contact member by the gas-fluid contact device. In some embodiments, the control system is further configured to control absorption of the gaseous activating agent by the fluid. The present disclosure also provides methods of treating a fluid including a biological liquid or cells with a gaseous activating agent to controllably activate the fluid.

A computer-implemented method comprises providing a fluid circuit comprising fluid pathways configured to mount and associate with a durable processing device comprising a pressure sensor in communication with a controller and a fluid pathway. A container is connected to the pressure sensor and may receive a volume of fluid. A change in pressure values between a first and second time is measured from when the volume of fluid is not in communication with the pressure sensor to when the volume of fluid is in communication with the pressure sensor, the volume of fluid within the container or a presence or absence of a fluid connection to the fluid pathway based on the change in pressure values is determined, and a response action is executed if the volume of fluid within the container is not within an authorized volume range for the time period, or if a fluid connection is unauthorized.

A medical contact shock freezer adapted for fast freezing a plurality of individual bags containing a medical liquid has the contact surface of its upper freezing plate arranged at an angle of at least 2° to the horizontal.