A61M1/0281

RETAINING TABLE FOR FLUID PROCESSING SYSTEM
20220143620 · 2022-05-12 ·

A retaining table for use with a fluid processing system includes a plate having a generally flat top surface with opposed first and second ends and opposed first and second lateral edges for supporting a disposable container, a first retaining structure connected to the plate along the first end, and a second retaining structure connected to the plate along the second end.

Disposable interconnected pump cassettes having first and second pump chambers with valved inlet and outlet connections

A system and method for pumping fluid using a set of interconnected pump cassettes is disclosed. Each of the pump cassettes can receive a first solution in a first pumping chamber and each of the pump cassettes can receive separate second solutions in respective second pumping chambers, so that the first solution can be mixed with the separate second solutions, each said mixture capable of being placed in separate containers. The system includes a control assembly for operating each pump cassette, each pump cassette having a flexible membrane to pump fluid into and out of the pumping chambers, and each pump cassette configured for mating with a base unit that provides positive or negative pneumatic pressure to the flexible membrane.

CELL HARVESTING APPARATUS

Disclosed herein is a cell harvesting instrument suitable for concentrating cells from a source suspension of cells and/or washing said cells, the instrument comprising: a housing for accommodating mechanical elements including at least one fluid pump, at least one valve; and a processing kit removably insertable into the housing, said kit including a generally flat frame having or supporting plural sealed fluid paths arranged in a generally flat plane and such that fluids in the paths do not contact said mechanical elements, wherein at least portions of the fluid paths comprise flexible tubes, the outer surfaces of which are manipulatable by the or each fluid pump, to provide fluid flow in one or more of the paths and/or by the or each valve to restrict fluid flow in one or more of the paths. In an embodiment, the kit comprises also a fluid processing reservoir and a filter suitable for separating cells from fluid in said paths. A transfer mechanism for moving and weighing the fluid processing reservoir is disclosed also.

MODULAR LIGHT DEVICE FOR A BIOLOGICAL FLUID TREATMENT SYSTEM
20220118136 · 2022-04-21 ·

Provided herein are systems and methods for implementing a modular light device for use in an electronic treatment device according to examples of the disclosure. In one or more examples, the modular light device can be implemented as a stand-alone component that can be swapped in and out of the treatment device. In one or more examples, the light device can include a light source array chamber configured to transmit UV light of a selected wavelength, the light source array chamber including one or more light source arrays and light sensors collectively configured as part of the light device to deliver light to a biological sample.

Bioprocessing system
11766508 · 2023-09-26 · ·

Disclosed is a bioprocessing system comprising apparatus (200) including a centrifugal separation housing (210) having a temperature controllable compartment (215) for removably accepting a separation chamber (50), the apparatus further comprising at least one mixing station (250) for supporting one or more fluid storage vessels (10, 20, 30, 40), the station including a temperature controllable area (252) for increasing or decreasing the temperature of the contents of the or each supported vessel. The system further includes a disposable fluidic arrangement (100) including a centrifugal separation chamber (50) removably mountable within the compartment (215) and having one or more ports (52) allowing fluid ingress into, or egress out of the chamber, via the one or more ports in use, said ports being in fluid communication with one or more of said fluid storage vessels via fluid conduits (12, 22, 32, 42) and via one or more valve arrangement.

Fluid mixing device and mixing method

Mixing device (1) and fluid mixing method, by means of successive transfers between syringes. The mixing method comprises placing a pair of syringes (2, 3) in the mixing device (1), adjusting a variable fixing element adaptable to the pair of syringes (2, 3) and selecting and running a mixing programme, being the mixing force, the speed and the range and the number of transfers adjustable. The mixing device comprises a mobile carriage (7) longitudinally movable and fixing elements (8, 9) with an adjustable distance between them. The invention allows for the mixing or emulsifying of blood fluids with different viscosity, particularly a protein gel and a platelet-rich plasma, for the preparation of dermatological formulations, in a versatile, hygienic and effective manner.

SYSTEM AND METHOD FOR CREATING CELL PROCESSING PROTOCOLS
20210353846 · 2021-11-18 ·

A method for creating a custom cell processing protocol includes providing a cell processing device having a display, a blood component separation device, and a pump. The method may then select, using the display, a first and second processing phase. The first processing phase has a plurality of first processing phase parameters and the second processing phase has a plurality of second processing phase parameters. The method may then modify the first and second processing phase parameters using the display, and create a custom protocol algorithm. The algorithm may be based, at least in part, on the selected first and second processing phases and the modified first and second processing phase parameters

SCREEN EXCHANGE DEVICE, BIOLOGICAL TISSUE SIZE REDUCTION SYSTEM COMPRISING SAME, BIOLOGICAL TISSUE SIZE REDUCTION METHOD USING SAME, AND METHOD FOR SEPARATING TARGET SUBSTANCE FROM RELEVANT BIOLOGICAL TISSUE
20210353837 · 2021-11-18 ·

A screen exchange device for reducing the size of a biological tissue according to one embodiment comprises: a disk comprising a plurality of screens each having at least one through-hole configured to reduce the size of a biological tissue, the screens having different through-hole characteristics; a first cover which covers a first side of the disk and includes a first opening through which a biological tissue passes; a second cover which covers a second side of the disk and includes a second opening through which the biological tissue passes; a housing configured to receive the disk; and a manipulator which selects any one screen among the plurality of screens and manipulates the first cover or the second cover such that the selected screen communicates with the first opening and the second opening.

DRY HEAT THAWING OF BIOLOGICAL SUBSTANCES
20210352768 · 2021-11-11 ·

A device for dry thawing biological substances and methods for using the same are provided. The dry thawing device can be configured to receive a biological substance within a woven pocket. The woven pocket can include temperature sensors configured to measure a temperature of the interior volume and heating elements configured to heat an interior of the woven pocket 106 based upon the measured temperature to avoid overheating or underheating the biological substance during thawing. The woven pocket can also include mechanical vibrators configured to agitate the biological substance during thawing to achieve an approximately homogeneous temperature profile within the woven pocket.

METHODS AND SYSTEMS FOR PROCESSING BIOLOGICAL FLUIDS
20220125043 · 2022-04-28 ·

Methods and container systems for processing biological fluids are disclosed. The container systems include an inner container within an outer container. The inner container wall is made of a porous material of a selected porosity that allows certain components to pass through said porous wall but retains other components. A treating solution is introduced into the chamber of the outer container.