This invention is directed to system and methods for the oxygenation of the blood of a patient, comprising an extracorporeal blood circulation path adapted to be coupled to the patient's vascular system, and comprising apparatus for oxygenating blood flowing therein and withdrawing CO2 therefrom, wherein the flow rate of blood flowing in said extracorporeal blood circulation path does not exceed of the patient's blood flow. The extracorporeal blood circulation path preferably comprise a cartridge including an oxygenator and at least one cannula.

A fluidic cartridge for use with a dialysis system, a method of manufacturing the fluidic cartridge, a dialysis machine and a method of operating the dialysis machine with the fluidic cartridge. The fluidic cartridge has a data storage unit, the data storage unit stores data relating to one or more physical properties of the cartridge. A cartridge for use in a portable dialysis machine and a portable dialysis machine. The cartridge has a data storage unit, the data storage unit stores data relating to sterilisation of the cartridge.

A peritoneal dialysis system includes a preparator and a cycler. The system delivers purified water into one or more containers with different powders to create a concentrate and then moves the concentrate to a mixing bag to create a peritoneal dialysis fluid (PDF). The cycler then delivers the PDF to a patient and removes waste fluid via a drain outlet. A volumetric approach controls hydraulic fluid paths that introduce the purified water to the powders to create the concentrate, provide mixing of the concentrate to form the PDF and deliver the PDF to the patient. Different configurations of hydraulic flow/pressure generators are provided in the fluid paths to provide optimization of flow of the purified water through the system to create correct concentrates from the powders and subsequent peritoneal dialysis fluid for cycling, for example being provided in a disposable cassette.

Damping devices, including damping devices for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, a damping device includes a body portion, a first membrane, and a second membrane. The body portion can include a first side, a second side opposite the first side, an inlet, and a cavity fluidly coupled to the inlet. The cavity can be defined at least in part by a lumen in the body portion extending from the first side to the second side. The first membrane can be affixed to the first side of the body portion such that the first membrane hermetically seals the cavity at the first side. The second membrane can be affixed to the second side of the body portion such that the second membrane hermetically seals the cavity at the second side.

An additive manifold includes a valve side including a plurality of valve mounts; and a tube fitting side including a plurality of integrally formed tube fittings. The additive manifold includes at least one passageway formed between the valve side and the tube fitting side, the at least one passageway allowing fluid communication between the valve mounts and the tube fittings.

A medical treatment system, such as a peritoneal dialysis system, may include a control and other features to enhance patient comfort and ease of use. For example, a cycler device may include a heater bag receiving section and a lid mounted to cover and uncover the heater bag receiving section, potentially enabling faster heating of a dialysate. A user interface may be moveable to be received into the receiving section and covered by the lid, if desired. The system may detect anomalous conditions, such as tilting of a housing of the system, and automatically recover without terminating a treatment. The system may include noise reduction features, such as porting pneumatic outputs to a common chamber, and others. The system may also automatically detect any one of several different solution lines connected to the system, and control operation accordingly, e.g., to mix solutions provided by two or more lines and form a needed dialysate solution. A cassette control surface may be arranged to have one or more ports that can detect a presence of a liquid, e.g., to identify if a cassette is leaking or has otherwise been compromised.

Damping devices, including damping devices for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, a damping device includes a body portion, a first membrane, and a second membrane. The body portion can include a first side, a second side opposite the first side, an inlet, and a cavity fluidly coupled to the inlet. The cavity can be defined at least in part by a lumen in the body portion extending from the first side to the second side. The first membrane can be affixed to the first side of the body portion such that the first membrane hermetically seals the cavity at the first side. The second membrane can be affixed to the second side of the body portion such that the second membrane hermetically seals the cavity at the second side.