Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

Apparatus for treating blood. A device (10) for separating plasma from blood comprises a blood flow path (20) including formations (24) for agitating blood flow along the blood flow path and a separation membrane (28) with a first surface in fluid communication with the blood flow path. The device may be comprised in an extracorporeal blood circuit and used in a method for separating plasma from blood.

Extracorporeal life support (ECLS) systems, devices and methods wherein a portable ECLS device is used to deliver cardiovascular support to a humans or animal patient (or harvested organ(s)) during pre-hospital or inter-hospital transport.

A dialysis machine comprising internal fluidics, wherein the internal fluidics includes a dialysis fluid pump for pumping dialysis fluid from a dialysis fluid reservoir through a dialysis fluid feed line to a dialyzer and from the dialyzer through a dialysis fluid drain line to a waste reservoir, a substitution fluid pump for supplying dialysis fluid through a substitution fluid feed line as substitution fluid to an extracorporeal hose system including ports on the patient side and coupling means for connecting the extracorporeal hose system to the internal fluidics is disclosed.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

A system for perfusing a localized site within a body includes a catheter assembly having a venous access line that is adapted to deliver perfusate to the localized site, a venous or arterial drainage line adapted to drain perfusate from the localized site, and an occlusion device adapted to prevent some or substantially all physiological blood flow between the localized site and the systemic circulation of the body during and in the course of perfusing and draining perfusate to and from the localized site. The system may include a blood circuit associated with the catheter assembly to facilitate blood conditioning for use as the perfusate, in the course of a controlled perfusion and/or drainage of untreated, treated, or inactivated treated blood to and from the localized site. A delivery machine may control the blood circuit and catheter assembly in order to both deliver perfusate to, and drain some or all perfusate from, the localized site in a manner that provides perfusate to substantially only the localized site.

Systems and methods are provided for determining an estimated risk of arrhythmia during or after dialysis based on changes in serum potassium concentration of a patient and an amount of fluid removed from the patient during dialysis. The systems and methods allow for a determination of a risk that arrhythmia will occur due to the changes in potassium and fluid volume of a patient during dialysis, and for optimizing a dialysis prescription in order to minimize the risk of arrhythmia.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

Disclosed is a method for treating a heart condition by perfusing a drug through an un-arrested beating heart of a patient. A closed circuit through the patient's coronary arteries and coronary venous system may be formed from a first drug delivery catheter (1822) positioned in the right coronary artery, a second drug delivery catheter (1824) positioned in the left coronary artery, a drug recovery catheter (1826) positioned in a coronary sinus, and an external membrane oxygenation system (1820) fluidly coupled to the various catheters. A drug for treating a heart condition may be perfused through the closed circuit.

The processes and equipment for collecting and recovering residual blood from cardiopulmonary bypass provide increased efficiency in hemoconcentrators and hemodialysers. Residual blood collection and recovery equipment for extracorporeal circulation circuits include a flow-limiting valve disposed at an exit of a hemofilter, which automatically regulates a resistance in a line as a function of an inlet pressure. The valves of the residual blood collection and recovery equipment also include an opening that is proportional to a flow and a hematocrit. The systems and methods for blood recovery can be used after surgery or for hemodialysis, in addition to other applications.