An adipose tissue (AT) transfer system includes, on the aspiration side, an aspiration cannula, an aspiration pump, a container, and flexible tubing connecting the aspiration cannula to the container. On the reinjection side, the system includes a reinjection cannula, flexible tubing connecting the inlet of the reinjection cannula to the container, and a reinjection pump imposing positive-displacement pumping action on the flexible tubing and causing movement of AT in a continuous or pulsed mode. The aspiration pump operates to continually supply harvested AT to the second flexible tubing while the reinjection pumps causes continuous or pulsed deposition of the AT at the injection site. To ensure that internal pressure and/or flow of the AT through a channel of delivery of the AT to the reinjection site does not exceed a predetermined value, defined with respect to pressure causing rupture of a blood-vessel at the recipient site, the system contains an external pressure sensor configured to measure such internal pressure in absence of a part that is in direct contact with the AT.

The present disclosure provides systems and methods for processing small volumes of tissue. The systems and methods include an interior fill volume and an exterior wash volume separated by a filter. Waste and fluids pass through the filter during tissue washing and transfer and can be absorbed or removed by application of negative pressure. The systems and methods are more portable and require fewer transfer steps than conventional methods, thus simplifying tissue processing procedures.

An adipose tissue (AT) transfer system includes, on the aspiration side, an aspiration cannula, an aspiration pump, a container, and flexible tubing connecting the aspiration cannula to the container. On the reinjection side, the system includes a reinjection cannula, flexible tubing connecting the inlet of the reinjection cannula to the container, and a reinjection pump imposing positive-displacement pumping action on the flexible tubing and causing movement of AT in a continuous or pulsed mode. The aspiration pump operates to continually supply harvested AT to the second flexible tubing while the reinjection pumps causes continuous or pulsed deposition of the AT at the injection site. To ensure that internal pressure and/or flow of the AT through a channel of delivery of the AT to the reinjection site does not exceed a predetermined value, defined with respect to pressure causing rupture of a blood-vessel at the recipient site, the system contains an external pressure sensor configured to measure such internal pressure in absence of a part that is in direct contact with the AT.

A method for processing biological material containing stringy tissue in a container having a tissue collector disposed in a tissue retention volume on one side of an internal filter includes washing biological material contained in the tissue retention volume with wash liquid to the tissue retention volume and allowing the wash liquid and rotating the tissue collector disposed in the tissue retention volume relative to the container in a first direction of rotation about an axis of rotation to sweep the teeth positioned on the tissue collector through the biological material and to collect stringy material on the tissue collector.

Embodiments of the present invention disclose micro-lipo needle device and methods of making and using the same.

Embodiments of the present invention disclose a device for removing adipose tissue with a needle(s), comprising a needle hub that comprises at least one needle that contains between 1-1000 holes around the circumference of the needle barrel which allows passage of adipose tissue and other lipoaspirate, and an adipose tissue collection and purification device comprising a plurality of self-contained syringes wherein each of the syringes comprises an inner syringe included within an outer syringe and wherein a filter is attached inside the outer syringe barrel, the filter having a mesh pore size between 30 micro meters and 1000 micro meters, the device being attached to a needle hub. The present invention further provides a system for closed adipose tissue harvesting, purification, and grafting, comprising an adipose tissue removal component, a collection and purification component, and a grafting component. Methods of using the devices or system are also disclosed.

An illustrative embodiment of a tissue separation and equalization device includes a generally elongated tissue insertion member; at least one tissue separating member opening in the tissue insertion member; at least one elongated tissue separating member having at least one flexible or bendable expansion segment, respectively, extending longitudinally within the tissue insertion member generally adjacent to the at least one tissue separating member opening, respectively; and a driving mechanism engaging the at least one tissue separating member and operable to displace the at least one tissue separating member within the tissue insertion member and expand or buckle the at least one expansion segment outwardly from the tissue insertion member through the at least one tissue separating member opening, respectively.

A system and method are provided for minimally-invasive selective fat removal from a target area by injecting the area with a solution of photo-absorbing nanoparticles and irradiating the injected area with a beam of near infrared (NIR) light. The NIR emission wavelength excites the nanoparticles to melt fat within the target area so that the liquefied fat can be aspirated from the target area. The nanoparticles may be gold nanorods having aspect ratios selected to produce surface plasmon resonance when irradiated with NIR light around 800 nm.

Embodiments of the present invention disclose a device for removing adipose tissue, comprising a self-contained syringe device comprising an inner syringe included within an outer syringe and wherein a filter is attached inside the outer syringe barrel; wherein the filter comprises a filter material that prevents premature filter collapse where the filter material is optionally coated to increase stiffness, and wherein liposuctioned adipose tissue is collected and purified inside the syringes. Methods of using the devices or system are also disclosed.

The present invention provides a device configured to mechanically remove a fat phase from at least one adipose tissue, the device comprising a first pressing element and a second pressing element. Furthermore, there is provided a method for preparing a preparation comprising a fat-depleted adipose tissue, the method comprising: mechanically removing a fat phase from at least one adipose tissue. In addition, there is provided a preparation comprising a fat-depleted adipose tissue, wherein the fat-depleted adipose tissue is prepared by mechanically removing a fat phase from at least one adipose tissue.