Embodiments of the present invention disclose a method of cosmetic or biomedical application of a device, comprising a self-contained syringe device comprising an inner syringe included within an outer syringe and wherein a filter is attached inside the outer syringe barrel; wherein the filter comprises a filter material that prevents premature filter collapse where the filter material is optionally coated to increase stiffness, and wherein liposuctioned adipose tissue is collected and purified inside the syringes.

Disclosed are methods and devices for processing lipoaspirate that include mechanically-processing harvested lipoaspirate in a liposuction filter canister. In some embodiments, the devices are liposuction devices that include a lipoaspirate processing unit for mechanically-processing lipoaspirate. The mechanical processing reduces the average size of adipose tissue pieces in the lipoaspirate without substantially rupturing lipocytes therein.

A fat cutter and an integrated machine for preparation of in vitro fine-particle fat are provided. The fat cutter includes a fat inlet channel, a fat outlet channel, at least one set of blades disposed between an outlet of the fat inlet channel and an inlet of the fat outlet channel, and a housing that seals a space in which the outlet of the fat inlet channel, the inlet of the fat outlet channel, and the blades are located. A fat inlet of the fat inlet channel is connected to a large-diameter liposuction tube by a liposuction channel, and a fat outlet of the fat outlet channel is connected to a high-negative pressure device. The outlet of the fat inlet channel and the inlet of the fat outlet channel are oppositely provided, and a gap therebetween matches the thickness of the blades.

A closed system for harvesting fat through liposuction, concentrating the aspirate so obtained, and then re-injecting the concentrated fat into a patient comprises as its main components a low pressure cannula having between about 7 to 12 side holes of about 1-2 mm by 2.0 to 4.0 mm, a spring loaded syringe holder with a constant force or coiled ribbon spring to apply a substantially constant pressure over the full excursion of the plunger, and a preferably flexible collection bag which is also preferably graduated, cylindrical over most of its body and funnel shaped at its bottom, all of which are connected through flexible tubings to a multi-port valve. The multi-port valve has two flutter/duck bill valves which restrict the fluid flow to a one way direction which effectively allows the syringe to be used to pump fat out of a patient and into a collection bag in a continuous manner. After the bags are centrifuged to concentrate the fat, the excess fluids are separated and the valve is re-connected to permit the syringe pump to reverse fluid flow to graft the concentrated fat back into the patient.

Systems, devices, and methods of the present disclosure assist with management of tubes and hoses during surgical procedures. The systems, devices, and methods provide for the proper opening and closing of tubes to facilitate performance of steps in a surgical procedure. Systems, devices, and methods of the present disclosure control fluid delivery to and from a medical device, including devices for tissue processing and cleaning.

Methods and devices are disclosed for processing stromal precursor cells (i.e., cells which can differentiate into connective tissue cells, such as in muscles, ligaments, or tendons) which can be obtained from fatty tissue extracts obtained via liposuction. Normal processing of a liposuction extract involves centrifugation, to concentrate the stromal cells into a semi-concentrated form called “spun fat”. That “spun fat” can then be treated by mechanical processing (such as pressure-driven extrusion through 0.5 mm holes) under conditions which can gently pry the stromal cells away from extra-cellular collagen fibers and other debris in the “spun fat”. The extruded mixture is then centrifuged again, to separate a highly-enriched population of stromal cells which is suited for injection back into the patient (along with platelet cells, if desired, to further promote tissue repair or regeneration).

An adipose tissue particle processing system includes a container and a filter screen assembly. The filter screen assembly has a first open end configured to receive adipose tissue from a syringe, and a second closed end opposite to the first open end located in the interior of the container. The filter screen assembly further includes a screen portion between the first open end and the second closed end, the screen portion including a plurality of apertures having diameters selected for processing the adipose tissue received through the first open end into controlled fat aspirate particle sizes that are output through the plurality of apertures into the interior of the container.

A method of processing an adipose tissue material sample to create and collect fat aspirate particles having particle diameters less than or equal to a selected size includes providing the adipose tissue particle sample in a syringe, and connecting a proximal end of a transfer cannula to the syringe. A filter screen assembly having a first open end, a second closed end, and a screen portion therebetween is inserted into an interior of a container. The screen portion includes a plurality of apertures having diameters of the selected size. The transfer cannula is inserted into the filter screen assembly and positioned to leave selected apertures of the filter screen assembly unobstructed by the transfer cannula. Adipose tissue material is then expelled from the transfer cannula through the apertures of the filter screen assembly into the container to create and collect the fat aspirate particles having controlled maximum particle diameters.

An isolation device for adipose-derived stromal vascular fraction is provided. More particularly the embodiments relates to novel systems, devices, methods and kits for adipose tissue collection and stromal vascular fractions isolation from collected adipose. The devices and systems are used in the field of healthcare/regenerative medicine.

The present invention relates to a device for use in processing fatty tissue, characterised in that it comprises, in a closed circuit, a first tissue collection unit (1) connected to a second tissue collection unit (2), wherein the first tissue collection unit (1) has an opening (3) that allows the inlet of tissue and an opening (4) in the base of the first unit that allows the outlet of tissue, and wherein the second tissue collection unit (2) has an opening (6) in the base of the second unit that allows the outlet of tissue.