The present application provides methods of restoring connective tissue in a patient, utilizing a combination of imaging techniques and minimally invasive tissue remodeling and regeneration, in combination with regenerative proteins. The methods provide a method for treating pain, mobility constraints, and stiffness issues across the interstitial layer (from head to toe), and in various joints and other areas where connective tissues are present. Also provided are kits for carrying out the various methods described herein.

The present invention relates to a liquid drug injection device for injecting a liquid drug into a nasal cavity and paranasal sinuses through a nostril and, more specifically, to a device for injecting a liquid drug into a nasal cavity and paranasal sinuses, so as to enhance the effect of cleaning surfaces of the nasal cavity and the paranasal sinuses and injecting the liquid drug, and to increase the effectiveness of preventing and treating nasal diseases.

A method of removing a kidney stone from the kidney and ureter of a human includes the steps of introducing a laminar flowing fluid via a ureteroscope into the ureter or kidney and proximal the kidney stone and flowing inward toward the kidney and then switching the laminar flow to a turbulent flow which causes a reverse flow that moves the kidney stone in a direction away from the kidney and down the ureter toward the bladder where the stone may be removed using a wire basket. In one step the kidney stone may first be fragmented into smaller kidney stones or fragments prior to switching to the turbulent flow.

The invention relates to disposable pulse lavage/suction devices (100, 400, 600) and systems for orthopaedic surgery. The general principle of the invention starts from the need to provide irrigation and/or suction devices and systems, having a low environmental impact. For this purpose, it is desirable that the disposable elements of such devices and systems can be easily incinerated and/or recycled. To this end, the inventors have identified that the motor, the pump and the battery/cell of said devices and systems should not be part of the disposable elements. The inventors have noted that in hospital operating theatres or similar environments, electromedical apparatuses are found that comprise a pump driven by a motor. Said electromedical devices are powered by the mains. The invention proposes irrigation and/or suction devices and systems that do not directly consume electrical power in order to ensure the operation thereof, but that use the electrical power supply of electromedical apparatuses present in the hospital operating theatres.

An irrigation system includes a housing on which a trigger is movably mounted, a motor, an accumulator, a pump and a gearing arranged inside the housing. At least the motor and the accumulator are mounted in a drive unit which can be replaced.

A pneumatic vibrational injection apparatus suitable for use in a system for removal, delivery and/or transplantation of body tissues and other substances in medical procedures may include an apparatus housing having an air inlet chamber, an air outlet chamber, a connecting chamber connecting the air outlet chamber and the air inlet chamber and an injection chamber disposed between the air inlet chamber and the air outlet chamber. An injection nozzle may be disposed in fluid communication with the injection chamber. An injection cannula may be disposed in fluid communication with the injection nozzle. An inlet transducer wheel and an outlet transducer wheel may be mounted for rotation in the air inlet chamber and the air outlet chamber, respectively, of the apparatus housing. A vibration transducer may be disposed in physical contact with the inlet transducer wheel and the outlet transducer wheel. The injection nozzle may be disposed in physical contact with the vibration transducer.

A system and method to irrigate a user's auditory canal. A fluid can be dispensed from a reservoir through a fluid path and out through openings of a delivery element into the auditory canal. A pump may be used to facilitate the process of dispensing the fluid. The fluid can be delivered to the user's auditory canal for a predetermined period of time. Such a time period may be user selectable. The discharge from the irrigation is removed from the user's auditory canal via a discharge port located on the delivery element. The discharge exits the delivery element and proceeds to a discharge reservoir via a discharge path. A vacuum may be used to generate a negative pressure to facilitate the removal of the discharge from the auditory canal.

A system for aspiration includes an aspiration catheter including an elongate shaft including an aspiration lumen, and an open distal end, an extension tube, the lumen of the extension tube configured to be hydraulically coupled to the aspiration lumen, a peristaltic pump configured for driving fluid through the extension tube, a compressible portion disposed between the distal end and the proximal end of the extension tube, the compressible portion configured to be coupled to the peristaltic pump, such that operation of the peristaltic pump drives fluid from the aspiration lumen from the distal end of the extension tube to the proximal end of the extension tube, and a controller configured to receive a first signal from the first sensor and configured to vary the operation of the peristaltic pump based at least in part on a first signal received from a first sensor coupled to the aspiration lumen or extension tube related to a change in the characteristic of flow.

The present application relates to a hydraulic assembly of a generator of medium-pressure and high-pressure pulsed or non-pulsed jets. The hydraulic assembly includes a hydraulic pipe with a flexible deformable zone. The flexible deformable zone can have a state of rest and a shut-off state. The hydraulic assembly includes a unit configured to hold the hydraulic pipe with a first clamp and a second clamp holding the hydraulic pipe on each side of the flexible deformable zone. The unit can form an open space between the first clamp and the second clamp.

A pneumatic vibrational injection apparatus suitable for use in a system for removal, delivery and/or transplantation of body tissues and other substances in medical procedures may include an apparatus housing having an air inlet chamber, an air outlet chamber, a connecting chamber connecting the air outlet chamber and the air inlet chamber and an injection chamber disposed between the air inlet chamber and the air outlet chamber. An injection nozzle may be disposed in fluid communication with the injection chamber. An injection cannula may be disposed in fluid communication with the injection nozzle. An inlet transducer wheel and an outlet transducer wheel may be mounted for rotation in the air inlet chamber and the air outlet chamber, respectively, of the apparatus housing. A vibration transducer may be disposed in physical contact with the inlet transducer wheel and the outlet transducer wheel. The injection nozzle may be disposed in physical contact with the vibration transducer. A syringe plunger may slidably engage the injection chamber in the apparatus housing.