A medicament delivery device having a reservoir for holding a medicament, a pressurizing system that dispenses the medicament from the reservoir when operating, a hollow cannula for insertion into a patient, and a fluid delivery path disposed between the pressurizing system and the hollow cannula and communicating the medicament therebetween. The medicament delivery device also has a pressure sensor external to the pressurizing system, sensing a back pressure in the fluid delivery path, and providing an indication when the back pressure drops below a predetermined threshold after the pressurizing system ceases operation.

A drug delivery device includes a blunt cannula and a reservoir. The blunt cannula has a cylindrical wall that defines an axial passage between a first end and a second end of the blunt cannula. The wall has at least a first tapered region at the first end to define an opening in fluid communication with the axial passage and adapted at the first end to resist interruption of fluid flow through the axial passage and out of the first end of the blunt cannula. The reservoir is connected to the second end of the blunt cannula.

A drug delivery device includes a blunt cannula and a reservoir. The blunt cannula has a cylindrical wall that defines an axial passage between a first end and a second end of the blunt cannula. The wall has at least a first tapered region at the first end to define an opening in fluid communication with the axial passage and adapted at the first end to resist interruption of fluid flow through the axial passage and out of the first end of the blunt cannula. The reservoir is connected to the second end of the blunt cannula.

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Some embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. The device comprises a capsule sized to be swallowed and pass through the intestinal tract. The capsule can include at least one guide tube, one or more tissue penetrating members positioned in the guide tube, a delivery member, an actuating mechanism and a release element. The release element degrades upon exposure to various conditions in the intestine so as to release and actuate the actuating mechanism. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade within the wall to release the drug to produce a therapeutic effect. The preparation can be coupled to an actuator having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Some embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. The device comprises a capsule sized to be swallowed and pass through the intestinal tract. The capsule can include at least one guide tube, one or more tissue penetrating members positioned in the guide tube, a delivery member, an actuating mechanism and a release element. The release element degrades upon exposure to various conditions in the intestine so as to release and actuate the actuating mechanism. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade within the wall to release the drug to produce a therapeutic effect. The preparation can be coupled to an actuator having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

A device for administering an infusion or transfusion of liquid from a container includes a pump for pumping liquid to a patient connection via a conduit having a liquid-retaining filter membrane. The device also includes a pressure measuring device for acquiring measurement values corresponding to a pump-inlet-side pressure, and a control device for detecting a change in the pump-inlet-side pressure based on the measurement values. The control device determines, based on the change in the pump-inlet-side pressure, whether to stop pumping. The control device also generates a control signal when the pumping is to be stopped. Moreover, the control device emits, based on the control signal, a communication signal to a data connection between the device and a unit that reads the communication signal. In addition, or in the alternative, the control device switches the device from a first state to a second state based on the control signal.

A drug delivery device (1), comprising a delivery unit (3) including a drug container (6), a liquid flow system (7), a pumping system (8), and a casing (9) enclosing therein the drug container, the pumping system and at least a part of the liquid flow system, the drug container comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion, the liquid flow system (7) connected fluidically to the drug container during delivery of the liquid drug. The drug container is contained within a container receiving cavity (75) of a container casing portion (38) of the casing (9) and the container receiving cavity is fluidically interconnected to a fluid outlet (31) of the pumping system (8) in a gas tight manner, the pumping system comprising a fluid inlet (30) connected to environmental air, the pumping system configured to pump environmental air drawn in through the fluid inlet (30) into the container receiving cavity (75) thus applying pressure on a back end (73) of the plunger for delivery of the liquid drug.

Drug delivery device (1) comprising a delivery unit (3) including a drug container (6) comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing against an inner surface of the barrel portion (6a) for containing a liquid drug (78) within the drug container; an electronic control system (47) and a plunger sensing system (70) including an optical sensor (71) comprising a transmitter (71a) and a receiver (71b), the transmitter configured for transmitting an optical signal to a back end (73) of the plunger (12) and the receiver configured to receive the optical signal reflected off the plunger back end (73), the plunger sensing system connected to the electronic control system (47) configured to measure a time of flight of the optical signal from the transmitter to the receiver and to determine therefrom a position of the plunger within the cylinder portion of the drug container.