Certain configurations of devices and systems that can administer a nuclear medication in an automated manner are described. In some instances, the system can receive a nuclear medication in a shielded transport container and administer the nuclear medication to a patient through an intravenous line in an automated manner to minimize radiation exposure by staff. Methods of using the devices and systems are also described.

A protection device for a syringe having a syringe body extending along a longitudinal axis comprising, at a first end an end tip including an orifice for the passage of liquid and, at a second end, an opening for the passage of a piston provided with a maneuver head; wherein the device is adapted to at least partially cover said syringe body and is made at least in part of a radioprotective material providing protection against ionizing radiation, and wherein the device is in the form of a clamp comprising two half-jaws joined together by a hinge, which clamp includes operating means configured so that said half-jaws are moveable between: a closed operative position, in which said half-jaws are assembled to form a cylinder to at least partially cover said syringe body, and an open inactive position, adapted for the introduction and extraction of said syringe body into said half-jaws.

Disclosed is a system for injecting a radioactive product to a patient, wherein the system includes: a first syringe containing the radioactive product, whose plunger cooperates with an injection mass, acting by gravity, associated with deactivatable holding element; a mobile stop arranged to constitute an end-of-travel stop for the retraction of the plunger, as a function of the volume of radioactive product to be injected to the patient; a second syringe containing a rinsing product, whose plunger cooperates with a rinsing mass, acting by gravity, associated with deactivatable holding element; a trigger control element for triggering the injection of the radioactive product to the patient; and a management element including a unit for displacing the mobile stop structure as a function of the prescribed activity to be injected to the patient, and a unit for controlling the deactivatable holding element of the masses.

The present disclosure relates to a device (1) for sampling and/or injection of a radioactive solution (S) in a vial (2), wherein the vial (2) comprises an opening closed by a puncturable closure member (3). The device (1) comprises a container (7) adapted to receive said vial (2) and a vial adaptor (4), said vial adaptor (4) having a longitudinal axis (L1), provided at a first end (41) with a hollow spike (42) adapted to pierce said puncturable closure member (3) when the vial adaptor (4) is mounted on the vial (2), and at a second end (43) with connection means (5) adapted for its removable connection to a syringe (6),
the container (7) comprising: a container body (71) adapted to receive said vial (2), the container body (71) having an opening (711), and a vial adaptor support structure (72) configured for being mounted onto the opening (711) of the container body (71), and comprising retention means configured for enabling releasable retention of said vial adaptor (4) within said vial adaptor support structure (72), and wherein the vial adaptor support structure (72) and the container body (71) are made at least partially of a radioprotective material for providing protection against ionizing radiation.

Methods and systems for selection of dosimetry levels and sphere amounts of radioactive compounds for use in a radioembolization procedure for procedure planning may include inputting activity parameter information into a dosimetry portal of a dosimetry selection tool; determining a customized activity based on the activity parameter information and one or more customized activity algorithms; generating one or more sphere amount and dosage recommendations based on the customized activity and one or more dosimetry selection algorithms; selecting one of the one or more sphere amount and dosage recommendations as a selected sphere amount and dosage recommendation; and generating a radioactive compound order for the radioembolization procedure based on the customized activity and the selected sphere amount and dosage recommendation.

A shield for a syringe containing biohazardous material includes an elongate body comprising a compartment extending longitudinally therethrough from a body cold end to a body hot end, the compartment dimensioned to receive a syringe barrel; a cold end cover dimensioned to receive and enclose a syringe plunger extending beyond the body cold end, the cold end cover attachable at the body cold end for enclosing the compartment and the syringe plunger at the body cold end thereby to shieldingly contain the biohazardous material in the syringe at the body cold end; and a hot end cover attachable at the body hot end for at least enclosing the compartment at the body hot end thereby to shieldingly contain the biohazardous material in the syringe at the body hot end.

A dispensing device which disperses medicate through a needle across a zone within a body. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a reservoir in fluid communication with the needle, positioned within the housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with the reservoir-connecting conduit, and a linear drive attached to the needle or to the needle-receiving member. The fluid drive impel fluids from the second reservoir to the reservoir-connecting conduit and thus drives the therapeutic agent from the reservoir during the linear displacement of the needle towards the housing. Fluid communication from the therapeutic agent reservoir to the needle is maintained by the tubing during operation of the linear drive.

Apparatus and methods for delivering medicament to a patient. The apparatus may include elements with different capacities to attenuate or absorb sterilizing radiation. The apparatus may include a medicament delivery assembly with interactive elements for dose-setting, priming and medicament ejection. The assembly may include a chamber housing a radiation-sensitive medicament present in the apparatus during sterilization by electron beam. The assembly may include an actuator chassis, a drive mechanism, a needle-priming mechanism and a fluid-displacement mechanism including a fluid-displacement member. The chassis may be fixed, relative to an outlet, to the chamber. The member may be slidingly and/or threadingly engaged with the chassis, and may be configured to move relative to the outlet to deliver the medicament through the outlet. Assembly elements may be nested coaxially and/or stacked axially. The assembly may include at least one hollow region. The hollow region may reduce beam attenuation or reduce radiation absorption.

In the present disclosure, embodiments of dual-stage syringes are disclosed along with delivery systems incorporating the dual-stage syringes. Embodiments of the dual-stage syringes described herein include sleeved dual-stage syringes, turn-key dual-stage syringes and dual-stage syringes including one or more one-way valves.

Certain configurations are described of devices that can receive and retain a radiation measuring device during administration of a nuclear medication. In some instances, the radiation measuring device can measure radiation levels being delivered through an intravenous line positioned within the device and connected to a patient. Methods and systems using the devices are also described.