A safety catheter insertion assembly including a catheter hub coupling assembly. The safety catheter insertion assembly having a needle hub slideably coupled to a needle housing such that the needle hub is moveable between a first position wherein an insertion needle extends from the needle housing, and a second position wherein the sharp distal tip is housed within the needle housing, the catheter hub coupling assembly coupling the catheter hub to the needle housing in the first position and releasing the catheter hub from the needle housing in the second position.

Described herein are cryolipolysis devices, systems, and methods for facilitating percutaneous access to a target blood vessel by performing cryolipolysis on subcutaneous adipose tissue obscuring the target blood vessel (e.g., a vessel used for hemodialysis treatment). Generally, the devices include a cooling member carrying a coolant that cools a selected portion of adipose tissue overlying the target blood vessel to reduce the selected portion of adipose tissue, thereby forming a depression in the adipose tissue and allowing the target blood vessel closer to the surface of the skin. In some variations, the cooling member is placed subcutaneously to directly cool the selected portion of adipose tissue. In other variations, the cooling member is placed external to the patient to indirectly cool the selected portion of adipose tissue through the skin.

A device and method for collecting blood from a mammalian digit, the device including a rigid cradle portion structured and arranged to retain the digit, a first biasing device releasably attachable to the cradle portion, a housing portion releasably connectable to the cradle portion, and a plurality of vibrating motors located beneath the cradle portion within the housing portion, such that vibrations translated to the digit enhance blood collection, such that the first biasing device constricts blood flow to the collection point on the digit, causing blood to pool therein, and low frequency and/or high amplitude vibrations cause vasodilation, encouraging blood flow through the capillaries at the collection point.

A lightweight, portable, cost-effective skin-cooling device is adapted for use with a coolant spray in an existing canister having a rim surrounding a push-activated spray tube. The apparatus comprises a housing with an inlet end that snaps onto the existing canister, an outlet end with a skin-contacting component, and a pushbutton. A tubular structure, disposed within the housing, includes an inlet end configured to engage with the push-activated spray tube of the canister, and an outlet end directed toward the skin-contacting component supported over the outlet end of the housing. Depressing the pushbutton causes the inlet end of the tubular structure to depress the push-activated spray tube, thereby causing the coolant spray to be carried though the tubular and out the outlet end thereof to cool the skin-contacting component.

In an embodiment, a syringe needle comprises a helical portion located in between a needle tip portion and a distal portion. In another embodiment, a compliant article comprises a casing tube comprising a tube end opening located at a needle tube end of the casing tube, a distal tube opening located at a distal tube end of the casing tube, and an inner tube space; and a syringe needle that traverses the tube end opening; wherein the compliant article comprises a compliant portion that allows for a reduced insertion pressure of the syringe needle as compared to an insertion pressure of a corresponding syringe needle in an article without the compliant portion.

A needle assembly is disclosed, for use with an injection device. The needle assembly comprises a needle hub (20) having a needle (22) and a needle shield (40) arranged for relative axial movement with respect to the needle hub, between a retracted position in which the tip of the needle projects beyond a forward end of the shield and an extended position in which the tip of the needle does not project beyond the forward end of the shield. The needle shield (40) is axially biased towards the extended position. The needle shield (40) is further arranged to be torsionally biased for relative rotational movement with respect to the needle hub (20).

A medicament delivery device includes a main injection needle for injecting a medicament into the body of a patient. The medicament delivery device includes a pain reduction device for releasing a pain reduction agent into the body of the patient prior the medicament injection. The pain reduction device includes an array of microneedles.

A safety catheter insertion assembly including a catheter hub coupling assembly. The safety catheter insertion assembly having a needle hub slideably coupled to a needle housing such that the needle hub is moveable between a first position wherein an insertion needle extends from the needle housing, and a second position wherein the sharp distal tip is housed within the needle housing, the catheter hub coupling assembly coupling the catheter hub to the needle housing in the first position and releasing the catheter hub from the needle housing in the second position.

A controlled stimulation device used either alone or in conjunction with a treatment device to reduce amount of pain a patient may experience during a treatment with the treatment device.

A pain-reducing injection apparatus to enhance the safety, efficacy, and efficiency of injection procedures which utilize topical pain-reducing measures. Apparatuses and methods of use provide pain reduction through thermal cooling of an injection region or vibrations the region or both, and optionally including safety shielding and lockout features.