A control circuit that operably couples to a display and to a nerve block injection pressure sensor provides a display of both a current nerve block injection pressure value and a current nerve block injection pressure categorical range. That categorical range can comprise, for example, one of a plurality of available categorical ranges which may be visually differentiated from one another by color. The control circuit can also detect (and display) a maximum nerve block injection pressure value (and/or calculate a mean nerve block injection pressure value) as corresponds to a given monitored nerve block injection procedure. The control circuit can also detect negative nerve block injection pressure events and identify those events as aspiration events to facilitate keeping a count of aspiration events during the course of a given nerve block injection procedure. The control circuit can also help ensure observe of the proper patient laterality if desired.

A syringe which has an intended pressure limit. The syringe includes a syringe body, and a pressure-limiting mechanism is disposed inside the syringe body. The pressure-limiting mechanism may comprise a valve body which is spring biased in the syringe body. In one embodiment, the pressure-limiting mechanism is provided in the form the valve assembly having a valve seal which moves into sealing engagement with an internal wall of a valve bore in the syringe housing once the intended pressure limit is reached. In another embodiment, the pressure-limiting mechanism is provided in the form of the valve assembly having a valve seat which moves into sealing or plugged engagement with a valve plug once the intended pressure limit is reached. Regardless of the exact configuration, preferably the syringe is simple, reliable, easy to assembly, and easy to sterilize given its low number of parts.

The present invention relates a botulinum toxin prefilled syringe system with desirable injection force characteristics, in particular low gliding force and low break loose force, comprising a syringe barrel of glass containing a liquid botulinum toxin composition, a plunger stopper and a closure device such as a tip cap or a needle shield. In addition, the present invention relates to a kit comprising the botulinum toxin prefilled syringe system, and optionally instructions for use, and to the use of the botulinum toxin prefilled syringe system in therapeutic and cosmetic applications.

A connector for connecting a container containing a medical fluid to a vascular access device may include an upper housing defining a first internal chamber, and a lower housing coupled to the upper housing and defining a second internal chamber for circulation of the medical fluid into the outlet. The connector may further include a slider disposed at least partially in the first and second internal chambers, and a plug coupled to a distal end of the slider. The slider may be reciprocally movable between (i) an open position, where the plug is spaced apart from a floor of the internal chamber to allow the medical fluid to flow through the outlet, and (ii) a closed position where the plug abuts the floor of the second internal chamber to block the medical fluid from flowing through the outlet.

Cellular therapy infusion devices for the delivery of media including cellular therapies to a patient's tissue, cells, and/or blood include a barrel, a plunger that fits within the barrel, a syringe shaft, and a pressure relief system configured to achieve and/or maintain a desired level of pressure and/or force within the device so that cellular behavior and/or viability is not adversely impacted by the mechanical forces exerted thereon via depressing the plunger into the barrel so the cellular therapy media may be pushed from the barrel into a patient delivery device for administration to the patient. The cellular therapy infusion devices may cooperate with and/or fit into cellular therapy infusion systems designed to create and/or maintain preferred conditions for the cellular therapy media stored in the barrel and automatically administer the cellular therapy media from the cellular therapy infusion device to the patient in a steady, regulated, and/or preferred manner.

A connector is disclosed that attaches an irrigation catheter to tubing of an anal or stomal irrigation system. The connector has a housing, a pressure control device retained within the housing, and a restriction element. The pressure control device has an inlet channel on a distal side of the pressure control device communicating along an irrigation flow path with an outlet channel on a proximal side of the pressure control device, and a secondary outlet located between the inlet channel and the outlet channel and in communication with the irrigation flow path. The restriction element is inserted into the secondary outlet.

A connector for connecting a container containing a medical fluid to a vascular access device may include an upper housing defining a first internal chamber, and a lower housing coupled to the upper housing and defining a second internal chamber for circulation of the medical fluid into the outlet. The connector may further include a slider disposed at least partially in the first and second internal chambers, and a plug coupled to a distal end of the slider. The slider may be reciprocally movable between (i) an open position, where the plug is spaced apart from a floor of the internal chamber to allow the medical fluid to flow through the outlet, and (ii) a closed position where the plug abuts the floor of the second internal chamber to block the medical fluid from flowing through the outlet.

A needle-free connector assembly is provided that includes a main housing coupled to an indicator housing. A plunger is coupled to a bellows disposed in the main housing. An inlet port is disposed at an upstream end of the indicator housing and an outlet port is disposed at a downstream end of the main housing, with a valve disposed within the indicator housing and adjacent the inlet port. A switch member is slidingly disposed in the main housing, wherein the needle-free connector assembly provides both flow regulation and pressure indication when the switch member is in a downstream position and only pressure indication when the switch member is in an upstream position. Infusion sets and methods of operating a needle-free connector are also provided.

Apparatus for anal and/or stomal irrigation is provided, including an irrigation system, adapter and method. The irrigation system comprises a reservoir for an irrigation liquid; a tubing system with a first end connectable to the reservoir, and a second end connectable to a catheter or an adapter for provision of a first fluid path for the irrigation liquid between the reservoir and the catheter comprising a distal end for expelling irrigation liquid from the catheter; and a pump operable to pump the irrigation liquid from the reservoir to the second end of the tubing system, wherein the irrigation system comprises a mechanical pressure control device, the pressure control device having an inlet side and an outlet side, wherein the inlet side is connected to a reservoir side of the first fluid path and the outlet side is connected to a catheter side of the first fluid path, wherein the pressure control device is configured to keep liquid pressure on the outlet side less than a first pressure threshold.