A method and apparatus is provided for spraying a solution, such as a cleaning solution a barrier material, out of a spray canister device to a surface area of a human body. The spray canister device generally includes a removable sleeved cover element covering an inner canister element. The spray canister device with the removable sleeved cover is easy to carry and easy to spray, and can be handled manually or functions together with other devices.

A method and apparatus is provided for spraying a solution, such as a cleaning solution a barrier material, out of a spray canister device to a surface area of a human body. The spray canister device generally includes a removable sleeved cover element covering an inner canister element. The spray canister device with the removable sleeved cover is easy to carry and easy to spray, and can be handled manually or functions together with other devices.

An electronic cigarette including an atomization assembly and a base assembly. The atomization assembly includes a mouthpiece; a first seal ring; a first seal cover; an airflow regulation ring; a permanent seat; an O-shaped ring; an atomizer; a second seal ring; a funnel; a third seal ring; a spring; an e-liquid injector; a fourth seal ring; a second seal cover; a fifth seal ring; a press cover; a positive terminal; a first silicone pad; a connection cylinder; a cover plate; a sixth seal ring; an e-liquid tank; a seventh seal ring; a negative terminal; a first circular magnet; a first strip magnet; and a magnet cover. The battery assembly includes: a second circular magnet; a second strip magnet; a housing; a front cover plate; a press button; a back cover plate; a silicone plug; a battery; a control plate; a second silicone pad; and a LED cover.

A method and a wash, clean and dry system are provided for washing, cleaning and drying a surface region of a human body. The system includes a toilet seat assembly with a bidet assembly having a spray canister device for spraying the surface region with a solution, such as a skin protecting barrier solution, a cleaning solution or a medicated solution. In one aspect, the spray canister device can be movably insert into and out of the toilet seat assembly and is easy to operate and use. In addition, the bidet assembly further includes a spray nozzle assembly and a drying nozzle assembly, which are adapted to wash, clean and dry the region of the human body in three dimensional moments. The removable spray canister device with the removable sleeved cover element is thus easy to carry and be re-filled with new solutions.

A method and a wash, clean and dry system are provided for washing, cleaning and drying a surface region of a human body. The system includes a toilet seat assembly with a bidet assembly having a spray canister device for spraying the surface region with a solution, such as a skin protecting barrier solution, a cleaning solution or a medicated solution. In one aspect, the spray canister device can be movably insert into and out of the toilet seat assembly and is easy to operate and use. In addition, the bidet assembly further includes a spray nozzle assembly and a drying nozzle assembly, which are adapted to wash, clean and dry the region of the human body in three dimensional moments. The removable spray canister device with the removable sleeved cover element is thus easy to carry and be re-filled with new solutions.

Methods are provided for acutely treating migraine headache with or without aura. The methods comprise administering to a subject with migraine headache an effective dose of a liquid pharmaceutical composition comprising dihydroergotamine (DHE) or a salt thereof, wherein the dose is administered by an intranasal delivery device that provides, following intranasal administration, (a) a mean peak plasma DHE concentration (C.sub.max) of at least 750 pg/ml, (b) with a mean time to C.sub.max(T.sub.max) of DHE of less than 45 minutes, and (c) a mean plasma AUC.sub.0-inf of DHE of at least 2500 pg*hr/ml. Also provided are kits for acutely treating migraine with or without aura in which a liquid pharmaceutical composition comprising DHE or DHE salt is contained within a sealed vial that is attachable to a precision intranasal olfactory delivery device packaged therewith.

The invention relates to a small-volume jet nebulizer having a unibody housing and an atomizer. The unibody housing includes input and output ports on a nebulizer body with an internal chamber that is widest at the output port. The housing also forms an internal gas inlet. The output port may be sized to fit standard patient interface ports. The nebulizer includes an atomizer that fits over the internal gas inlet. The atomizer includes a siphon, a jet and a baffle set a distance above the jet by arms connected to the siphon.

Deformable valves and atomizer designs for a vaporizer (e.g., electronic cigarette). The vaporizer may be used for vaporization of liquid and/or organic material. The vaporizer may enable enhanced flow control of fluid and may generate high quality and quantity of vapor efficiently. In some instances, flow path of the vaporizer may allow bulk fluid flow, e.g., in contrast to capillary flow, to deliver fluid to a vicinity of the vaporizer. In some instances, the vaporizer may utilize improved atomizer designs for vaporizing devices, where said designs can be configured optionally, with various embodiments of a breath-modulating deformable valve.

Deformable valves and atomizer designs for a vaporizer (e.g., electronic cigarette). The vaporizer may be used for vaporization of liquid and/or organic material. The vaporizer may enable enhanced flow control of fluid and may generate high quality and quantity of vapor efficiently. In some instances, flow path of the vaporizer may allow bulk fluid flow, e.g., in contrast to capillary flow, to deliver fluid to a vicinity of the vaporizer. In some instances, the vaporizer may utilize improved atomizer designs for vaporizing devices, where said designs can be configured optionally, with various embodiments of a breath-modulating deformable valve.

Dose delivery device with partially or fully surrounding cover may be removed to open fluid communication with a dose chamber. The cover may allow an inhaler to be stored in sterile or otherwise in a controlled environment prior to use, and removal of the cover may automatically prepare the inhaler for use.