Provided is a system for providing an output for warning of a respiratory disease exacerbation in a subject. The system comprises a first inhaler for delivering a rescue medicament to the subject. The system optionally includes a second inhaler for delivering a maintenance medicament to the subject during a routine inhalation. A sensor system is configured to measure a parameter relating to airflow during the rescue inhalation and/or during the routine inhalation, when the second inhaler is included in the system. The system further comprises a processing module configured to monitor a frequency of the determined rescue inhalations. The processing module also monitors the parameter as a function of time. The processing module is further configured to provide the output for warning of a respiratory disease exacerbation if the parameter as a function of time is indicative of the lung condition of the subject deteriorating over a first time period, and the frequency of the determined rescue inhalations is higher during a second time period than during the first time period, the second time period being subsequent to the first time period. Further provided is a method for providing an output for warning of a respiratory disease exacerbation in a subject.

There is provided in accordance with an exemplary embodiment of the invention, a device and a method for controlled extraction of at least one active substance from at least one type of plant matter by application of heat, the device comprising: a heating element adapted to apply heat to an area of the plant matter to extract the substance; and a mechanism adapted for moving the plant matter relative to the heating element. Optionally, the active substance is a restricted substance. There is also provided in accordance with an exemplary embodiment of the invention, a method of monitoring and controlling inhalation of a restricted substance. There is provided in accordance with an exemplary embodiment of the invention, a method of manufacturing a tape of plant matter comprising an active substance.

A dry powder inhaler dispenses a partial dosage of a powder from a dry powder chamber during a single user inhalation. In certain embodiments, the dry powder chamber is a dry powder capsule that spins in a chamber with a protrusion for limiting the spin of the capsule. In certain embodiments, a capsule slides in a proximal and distal direction for dispensing partial dosages of powder medicament. Air inlets in communication whit the external environment can be included in the inhaler housing for generating a smooth inhalation experience for the user and facilitating operation of partial dosage mechanisms. In other embodiments, a hinged member, sliding member, rotating member, spring tensioned member, pressure actuated valve, dry powder chamber with patterned holes or combinations of these are used as a mechanism for dispensing a partial dosage of powder medicament during a single inhalation.

A smart dosing device includes: a supply pathway having a compartment that is able to house a plurality of discrete doses of a particular substance; at least one sensor that captures identifying information related to the particular substance; a wireless communication module; and at least one security feature that restricts use of the smart dosing device. A method of providing a measured dose using a smart dosing device includes: retrieving a discrete dose from a storage cavity of the smart dosing device; and providing the discrete dose via an outlet port of the smart dosing device. A smart dosing system includes: a smart dosing device having a unique identifier, the smart dosing device including a cartridge housing multiple discrete doses of a substance, the cartridge having a unique cartridge identifier; and a server including a central database that stores usage information related to the smart dosing device, the usage information comprising: the unique identifier and the unique cartridge identifier.

The present invention is directed to a system for dosing an inhaling composition. It is preferably integrated into an e-cigarette. The system comprises more than one component for the inhaling composition. A first container (30) can be provided for a first component for the composition. A second container (31) can be further provided for a second component for the composition. Moreover, a dosing arrangement (10, 11, 40) can be arranged that is configured to automatically reduce the dose of at least the second component over time.

The present invention is directed to a system comprising a mobile inhaler (1) that is configured to be simultaneously connected to at least one or a plurality of liquid containers (17) and to deliver an inhaling substance (10), wherein the inhaling substance comprises at least one of an amount of a first component (11) and an amount of a second component (12). The mobile inhaler further comprises at least one or a plurality of connector(s) (80) configured for connection of the mobile inhaler to the at least one or the plurality of liquid containers and for intaking of at least a portion of each of the liquid container(s)'s content(s). The system comprises furthermore the at least one or the plurality of liquid containers, wherein the at least one or the plurality of liquid containers comprises a plurality of reservoirs, wherein each reservoir comprises a component of the inhaling substance and wherein the reservoirs each comprise mutually different components of the inhaling substance. The present invention is furthermore directed to a method for operating the system, comprising delivering the inhaling substance by the mobile inhaler, wherein the mobile inhaler delivers at least the first component of the inhaling substance according to a set of conditions. Said set of conditions regulates at least one of a quantity and a general delivery of at least one of the first component and the inhaling substance.

A modular electronic inhaler having an embedded system and a method for precise and repeatable delivery of multiple types of medications in different forms to the pulmonary system of a human user. The inhaler can include a first MDI housing defining an internal chamber for accommodating a MDI medication cartridge and a second DPI housing defining an internal chamber for accommodating a DPI medication cartridge. Meter reservoir compartments in each housing can automatically provide precise doses of medicine using vacuum pressure sensors. The sensors can be in communication with the internal embedded system/electronics (microcontroller) of the inhaler and the electronics/microcontroller can be in permanent communication with a software application running on the user's smart phone or other electronic device.

The present disclosure includes a method for vaporizing a product of a plurality of different products including receiving, by a processor of a vaporizing device, a desired dosage amount that is indicative of an amount of a compound to release during one or more inhalation events. The method includes determining, by the processor, an occurrence of a current inhalation event and during the current inhalation event determining, by the processor, an inhalation pressure being applied to a container that contains the product; determining, by the processor, a predicted dosage that is indicative of a predicted amount of the compound that has been released in the vapor during the current inhalation event based on the inhalation pressure; and selectively adjusting, by the processor, a vaporizing temperature being applied to the product by the vaporizer based on the desired dosage and the predicted dosage.

Provided is a system and method for a dosing vaporizer. More specifically, an embodiment of the system includes a housing with a first end opposite from a second end. A mouthpiece disposed proximate to the first end, the mouthpiece structured and arranged to rotate about the first end. An attacher disposed proximate to the second end, the attacher structured and arranged for removable attachment to a power source. A reservoir of liquid concentrate is disposed within the housing. A vaporizer disposed proximate to the attacher and thermally isolated from the reservoir. A vapor conduit passes generally from the vaporizer through the housing to the mouthpiece. A metered rotation driven dispenser, coupled to the mouthpiece, applies a predetermined force upon the reservoir to dispense from the reservoir into the vaporizer a predetermined amount of liquid concentrate.

In general, systems and methods for controlling operation of drug administration devices using surgical hubs are provided.