A seal-forming structure for a patient interface may include a patient-contacting surface configured to engage the patient's facial skin to form a seal; a posterior opening formed in the patient-contacting surface, the posterior opening configured to provide the flow of air at said therapeutic pressure to the patient's nares; and a support structure extending from the patient contacting surface to an interior surface of the seal-forming structure, the support structure and the interior surface forming a continuous loop, wherein the patient interface is configured to allow the patient to breath from ambient through their mouth in the absence of a flow of pressurised air through the plenum chamber inlet port, or the patient interface is configured to leave the patient's mouth uncovered.

The present disclosure relates generally to the field of nicotine delivery. The disclosure teaches a nicotine meta-salicylate. More specifically, the disclosure teaches a condensation nicotine aerosol where nicotine meta-salicylate is vaporized. This disclosure relates to aerosol nicotine delivery devices. The delivery devices can be activated by actuation mechanisms to vaporize thin films comprising a nicotine meta-salicylate. More particularly, this disclosure relates to thin films of nicotine salt with meta salicylic acid for the treatment of nicotine craving and for effecting smoking cessation.

Inhalator comprising an aerosol generator configured to generate an aerosol by nebulizing a fluid and a controller configured to control operation of the aerosol generator and a housing accommodating at least the aerosol generator and the controller, the housing having a base for supporting the housing on a horizontal surface, wherein a portion of the housing accommodating at least a portion of the controller is arranged further away from the base than the aerosol generator as seen in a vertical direction, when the base is supported on the horizontal surface.

The present disclosure pertains to a method and system configured for cough synchronization in a mechanical insufflation-exsufflation system. The system is configured to synchronize (712) the transition from an insufflation mode to an exsufflation mode to a patient initiated cough by detecting cough effort of the patient e.g. at the end of the insufflation phase. The detection of cough effort of the patient is based on one or more parameters associated with gas in the system. Upon detecting that the patient is initiating a cough, the system automatically switches the insufflation mode to the exsufflation mode to assist the patient to generate an effective cough.

A seal-forming structure for a patient interface may include a patient-contacting surface configured to engage the patient's facial skin to form a seal; a posterior opening formed in the patient-contacting surface, the posterior opening configured to provide the flow of air at said therapeutic pressure to the patient's nares; and a support structure extending from the patient contacting surface to an interior surface of the seal-forming structure, the support structure and the interior surface forming a continuous loop, wherein the patient interface is configured to allow the patient to breath from ambient through their mouth in the absence of a flow of pressurised air through the plenum chamber inlet port, or the patient interface is configured to leave the patient's mouth uncovered.

An aerosol provision cartridge (30) for an aerosol provision system (10). The cartridge (30) comprises a refillable chamber (100) for aerosol precursor material, the chamber (100) comprising a first opening (102) and a second opening (104), each opening (102;104) allowing for access into the chamber (100). Each opening (102;104) is covered by a respective cap (130;132) which is configured to be uncoupled from the chamber (100) for allowing access to the opening (102;104). The cartridge (30) is configured such that each cap (130;132), when coupled to the chamber (100), requires at least two different actions (A1;A2) to be uncoupled from the chamber (100). The first or second action (A1;A2) may each include, but are not limited, to: rotating; pulling; pushing; or unlatching.

An object of the present invention is to provide a breathing apparatus, wherein current for keeping internal pressure of the face piece at a predetermined positive target value at the time of inhale is not applied to the motor fan in a large amount at the start of current application to the motor fan, and the internal pressure of the face piece is prevented from becoming far below the predetermined positive target value immediately after start of current application to the motor fan so as to keep the internal pressure of the face piece at the predetermined positive target value at the time of inhale. A breathing apparatus provided with a breath-synchronized motor fan comprising a face piece for covering a part of or all of a face of a user, an inhale valve and an exhale valve attached to the face piece, a motor fan for supplying internal space of the face piece with external air through the inhale valve, a filter for cleaning the external air to be sucked into the motor fan, a breath monitoring apparatus provided with a membrane member deforming in accordance with fluctuation of internal pressure of the face piece and a sensor for detecting the deformation of the membrane member, and a controller for controlling operation of the motor fan synchronously with breathing of the user in accordance with a detection signal from the breath monitoring apparatus, wherein the controller applies current to the motor fan at the time of inhalation so as to keep the internal pressure of the face piece at a predetermined positive target value, and stops current application to the motor fan so as to stop the motor fan at the time of exhalation, and wherein the controller applies micro-current to the motor fan so as to rotate the motor fan at extremely low speed from the middle of exhalation to inhalation.

A device for detecting a flow of a first gas in a conduit includes a gas jet interfaced to a side of the conduit. The gas jet emits a jet of gas aimed across the conduit. A fluid port is interfaced to a distal side of the conduit for receiving the jet of gas and a pressure-detecting device is interfaced to the fluid port. In absence of the flow of the first gas within the conduit, the gas jet enters the fluid port and the pressure-detecting device reports a first pressure. In presence of the flow of the gas within the conduit, the gas jet is deflected away from the main port by the flow of the first gas and the pressure-detecting device reports a second pressure, the second pressure being lower than the first pressure.

An aerosol provision system comprises a heating element for generating an aerosol from a source liquid and control circuitry for controlling a supply of electrical power from a power supply to the heating element. The control circuitry is configured to measure an indication of a derivative of an electrical characteristic of the heating element with respect to time. Based on the measured time derivative, the control circuitry is configured to determine whether or not a fault condition has arisen for the electronic aerosol provision system. The overall change in the electrical characteristic for the heating element caused by the localized heating may be small and so difficult to reliably identify, but the rate at which the change occurs can be expected to be relatively high, such that the time derivative of the local characteristic is a more reliable indicator of occurrence of the fault condition.

A seal-forming structure for a patient interface may include a patient-contacting surface configured to engage the patient's facial skin to form a seal; a posterior opening formed in the patient-contacting surface, the posterior opening configured to provide the flow of air at said therapeutic pressure to the patient's nares; and a support structure extending from the patient contacting surface to an interior surface of the seal-forming structure, the support structure and the interior surface forming a continuous loop, wherein the patient interface is configured to allow the patient to breath from ambient through their mouth in the absence of a flow of pressurised air through the plenum chamber inlet port, or the patient interface is configured to leave the patient's mouth uncovered.