A capsule for an aerosol-generating device may include a housing, a filter, and an aerosol-forming substrate. The housing may have a gas-permeable end and an impermeable end. The filter may be disposed within the housing so as to be adjacent to the impermeable end. The aerosol-forming substrate may be disposed within the housing so as to be between the filter and the gas-permeable end. The housing may be configured to facilitate a heating of the aerosol-forming substrate via one of conduction, convection, or both conduction and convection so as to generate an aerosol.

An aerosol generating device is provided, including a storage portion to store an aerosol-forming substrate and having an outer housing and an internal passageway, the portion forming a reservoir for the substrate between the housing and the passageway; a vaporizer including an electric heater to heat the substrate to form an aerosol, the vaporizer at least partially inside the passageway; and a porous interface at least partially lining the passageway to convey the substrate towards the vaporizer, the device being electrically operated, the heater including first and second electrical connection portions, and a heating filament therebetween, a cylindrical shape of the connection portions and the filament define a cylindrical bore, an air flow route is defined through the bore, and the first connection portion being a first cylindrical electrical connection portion, the second connection portion being a second cylindrical electrical connection portion, and the filament being a cylindrical heating element.

The invention refers to a head and/or neck-mounted respiratory protection device (10) comprising a body-wearable elongated mount (12) for attaching the respiratory protection device (10) to the head and/or neck of a user, a reservoir (14) for storing a bioactive substance (30), and an aerosol generating device (16) connected to the reservoir (14) to receive the bioactive substance (30). The aerosol generating device (16) is configured for generating an aerosol comprising the bioactive substance (30) and for dispensing said aerosol into a respiration area in front of the mouth and nose of the user in order to provide a sterilising atmosphere therein. The invention further refers to a corresponding method of controlling a respiratory protection device.

Disclosed herein are formulations of pirfenidone or pyridone analog compounds for aerosolization and use of such formulations for aerosol administration of pirfenidone or pyridone analog compounds for the prevention or treatment of various fibrotic and inflammatory diseases, including disease associated with the lung, heart, kidney, liver, eye and central nervous system. In some embodiments, pirfenidone or pyridone analog compound formulations and delivery options described herein allow for efficacious local delivery of pirfenidone or pyridone analog compound. Compositions include all formulations, kits, and device combinations described herein. Methods include inhalation procedures, indications and manufacturing processes for production and use of the compositions described.

The present disclosure relates generally to the field of nicotine delivery. The disclosure teaches a nicotine meta-salicylate. More specifically, the disclosure teaches a condensation nicotine aerosol where nicotine meta-salicylate is vaporized. This disclosure relates to aerosol nicotine delivery devices. The delivery devices can be activated by actuation mechanisms to vaporize thin films comprising a nicotine meta-salicylate. More particularly, this disclosure relates to thin films of nicotine salt with meta salicylic acid for the treatment of nicotine craving and for effecting smoking cessation.

Systems and methods for novel ventilation that allows the patient to trigger or initiate the delivery of a breath are provided. Further, systems and methods for triggering ventilation based on signal distortion of a monitored patient parameter are provided.

A capsule for an aerosol-generating device may include a housing, a filter, and an aerosol-forming substrate. The housing may have a gas-permeable end and an impermeable end. The filter may be disposed within the housing so as to be adjacent to the impermeable end. The aerosol-forming substrate may be disposed within the housing so as to be between the filter and the gas-permeable end. The housing may be configured to facilitate a heating of the aerosol-forming substrate via one of conduction, convection, or both conduction and convection so as to generate an aerosol.

Provided are methods for delivering psychedelic drugs to a patient in need thereof comprising administering via inhalation of a psychedelic drug in the form of an aerosol, methods for treating a central nervous system (CNS) disorder or psychological disorder via inhalation of a psychedelic drug in the form of an aerosol, devices for delivery of psychedelic drug and nitrous oxide mixtures by inhalation, including with remote activation and control, and methods for treating a central nervous system (CNS) disorder or psychological disorder via inhalation of nitrous oxide/oxygen mixtures having an amount of nitrous oxide of 15 to 25% by volume of total gas.

The technology relates to a variable flow vent assembly for a conduit mask configured to deliver a flow of breathable gas at a positive pressure to an airway entrance of a patient and allow a flow of exhaled gas from the airway of the patient to exit the vent assembly to ambient. The variable flow vent assembly is further configured to include a valve, wherein the valve is arranged to allow for the regulation of the flow of breathable gas to the patient and the regulation of the vent flow rate of exhaled gas leaving the vent assembly to ambient. By changing certain characteristics of the valve and by tuning the valve through variants in design, the resultant vent flow rate for a given air pressure can be altered in order to obtain the best treatment outcome for the patients individual requirements.

A breathable gas inlet control device permits flow regulation at the inlet of a flow generator for a respiratory treatment apparatus such as a ventilator or continuous positive airway pressure device. The device may implement a variable inlet aperture size based on flow conditions. In one embodiment, an inlet flow seal opens or closes the inlet to a blower in accordance with changes in pressure within a seal activation chamber near the seal. The seal may be formed by a flexible membrane. A controller selectively changes the pressure of the seal activation chamber by controlling a set of one or more flow control valves to selectively stop forward flow, prevent back flow or lock open the seal to permit either back flow or forward flow. The controller may set the flow control valves as a function of detected respiratory conditions based on data from pressure and/or flow sensors.