Embodiments herein include delivery systems for active agent coated balloons and related methods. In an embodiment, a delivery system can include a tunneling sheath and a balloon catheter. The tunneling sheath can include a tubular shaft having an outer diameter and defining a lumen. The tunneling sheath can include a proximal collar defining a lumen. The balloon catheter can include a balloon catheter shaft disposed within the tubular shaft. The balloon catheter shaft can include a lumen for the passage of a fluid therein. The balloon catheter can include an expandable balloon disposed on the balloon catheter shaft. The balloon catheter shaft can include an active agent layer disposed on the expandable balloon. The position of the expandable balloon can be configured to be stationary relative to the tubular shaft as the delivery system is passed through a blood vessel of a patient. Other embodiments are also included herein.

The invention generally relates to method and apparatus for crossing an obstruction in a tubular member, and more particularly to a medical device method for crossing of a chronic occlusion in a subintimal or interstitial space of an artery.

Apparatus for use in dialyzing a patient, the apparatus comprising: a hemodialysis catheter comprising: an elongated body having a proximal end and a distal end, wherein the distal end terminates in a substantially planar distal end surface; first and second lumens extending from the proximal end of the elongated body to the distal end of the elongated body, wherein the first and second lumens terminate on the substantially planar distal end surface in first and second mouths, respectively, arranged in side-by-side configuration, and further wherein the first and second lumens are separated by a septum; and first and second longitudinal slots formed in the distal end of the elongated body and communicating with the interiors of the first and second lumens, respectively, the first and second longitudinal slots opening on the substantially planar distal end surface; wherein the first and second longitudinal slots each has a length and a width, relative to the dimensions of the first and second lumens and the rate of blood flow to be passed through the hemodialysis catheter, such that (i) when a given lumen is to be used for a return function, the primary blood flow will exit the mouth of that lumen, and (ii) when a given lumen is to be used for a suction function, the primary blood flow will enter the proximal end of the longitudinal slot associated with that lumen, whereby to minimize undesirable recirculation of dialyzed blood.

Embodiments of the present disclosure provide a medical device for snaring guidewire during endovascular procedure. The medical device includes a catheter and an elongate member. The catheter is deployed into a lumen of a blood vessel through a first vascular access point of a subject. The elongate member includes a distal tip mounted with a first magnetic element and configured to be insertable within the catheter. The elongate member is deployed in the lumen of the blood vessel by advancing through the catheter. The first magnetic element of the elongate member is configured to exert magnetic force to magnetically couple with a guidewire advancing within the lumen through a second vascular access point. The magnetic coupling of the elongate member and the guidewire facilitates attracting the guidewire into the catheter and draw out from the first vascular access point by withdrawing the elongate member while advancing the guidewire.

A catheter that has a catheter tube everting inside-out during the process of catheterization is disclosed. The catheter tube has a plurality of longitudinal protrusions extending from the first end of the catheter tube through at least a portion of the catheter tube, and forming an angle of 0 degrees to 45 degrees with respect to the longitudinal axis of the catheter tube and facing radially inwards, and provides for dilating a circumference of the catheter tube upon everting the catheter tube inside-out from the first end of the catheter tube.

Embodiments of the invention are directed towards a rapid exchange catheter configured for insertion into a subintimal space and crossing an occlusion in a subintimal space. The catheter includes a proximal end, a distal end, a first lumen configured to receive a first wire, the first lumen extending longitudinally through a least a lateral port of the catheter, and a second lumen having at least a portion distal of the lateral port and extending through at least the distal end of the catheter. The catheter also includes an exchange port arranged on a exterior portion of the catheter configured to the receive a second wire and second rapid exchange port in communication with the second lumen. Moreover, other embodiments of the invention are directed towards methods for using the rapid exchange catheter to cross an obstruction in a vessel, e.g., a total or partial occlusion, in a subintimal space.

A biologics delivery device and method of use for promoting angiogenesis in occluded vessels and ischemic tissue of a patient are provided, wherein the biologics delivery device includes a catheter having a proximal end, a distal region having a distal end, a lumen extending there between, and a plurality of through-wall apertures distributed along the distal region, the plurality of through-wall apertures in fluid communication with the proximal end and the lumen, and an expandable member disposed in the distal region, the expandable member configured to transition between a collapsed state and an expanded state. Methods of using the inventive biologics delivery device also are provided to achieve substantially uniform distribution of the biologic into a subintimal space.

An arthroscopic tenodesis kit, includes a guide including an elongate member having a length with a distal portion having one or more spring arms configured to open toward a free end of the distal portion of the guide to directly and releasably engage a tendon. The kit also includes an inserter having an elongate cannulated body having an interior bore having a blind end and an open end configured to slidingly receive the guide. The body of the inserter has a length that is shorter than the length of the guide, so that the distal portion of the guide remains spaced from the bore when the guide is fully received within the bore.

An introducer sheath includes an elongated outer sheath and an elongated inner sheath coaxially disposed within the outer sheath. The elongated outer sheath includes an outer sheath wall extending circumferentially about a longitudinal axis of the outer sheath to an extent greater than 180° and less than 360° to define an outer sheath slot. The elongated inner sheath includes an inner sheath wall extending circumferentially about a longitudinal axis of the inner sheath to an extent greater than the difference between 360° and the circumferential extent of the outer sheath wall, and less than 360° to define an inner sheath slot. The inner sheath is rotatable relative to the outer sheath to form an enclosed lumen when the outer and inner sheath slots are not aligned, and to form an open slot along the entire length of the introducer sheath when the outer and inner sheath slots are aligned.

A split-tip catheter and methods for deploying a split-tip catheter in a right atrium are provided. The catheter is configured with a distal potion including a first and a second distal end regions elastically divergable from alignment along a splitting plane to regain a relaxed configuration. The first distal end region terminates in a first tip having a first forward opening, and the second distal end region terminates in a second tip having a second forward opening. Catheter deployment may include directing the first forward opening generally towards an anterior right atrium wall portion and applying the first forward opening to withdraw blood from the right atrium.