Disclosed herein are delivery systems and delivery assemblies comprising a co-extruded elongated polymeric sleeve comprising an inner polymer layer and an outer polymer layer, which form two lumens having a different diameter, wherein the inner polymer layer comprises a fluoropolymer; and wherein the outer polymer layer comprises a polyamide, or a polyether block amide, or a combination thereof. Also disclosed are methods of making and using the same.

A vapor delivery system is provided that may include any of a number of features. One feature of the vapor delivery system is that it can apply condensable vapor energy to tissue, such as a prostrate, to shrink, damage, or denature the prostate. In some embodiments, the vapor delivery system can include safety features including prostate capsule detection, needle tracking, and treatment tracking. Methods for safe and effective treatment of prostate tissues are presented.

A catheter system is disclosed. A catheter system comprises a catheter module and a magnetic robot, which can be coupled to the catheter module, wherein: the catheter module comprises a catheter having an accommodation space formed on the front end thereof, and a rotational magnet that is rotatable; and the magnetic robot comprises a body and a magnet member, which is coupled to the body and induces magnetism with the rotational magnet.

A microcatheter comprising an inner layer, a strike layer and an outer layer and a braided skeleton located between the inner layer and the outer layer, wherein the inner layer is made of Polytetrafluoroethylene (PTFE) and has a thickness of 0.0015 inch or less, wherein the strike layer includes a polyether block amide and has a thickness of 0.001 inch or less, and wherein a distal portion of said outer layer is made of polycarbonate-based thermoplastic polyurethane having a shore of 90A or below.

Described are methods, systems, devices for facilitation of intraluminal medical procedures within the neurovasculature. A catheter advancement device includes a flexible elongate body having a proximal end, a distal end, and a single lumen extending therebetween. The flexible elongate body has a proximal segment, an intermediate segment, and a tip segment. The proximal segment includes a hypotube coated with a polymer. The intermediate segment includes an unreinforced polymer having a durometer of no more than 72D. The tip segment is formed of a polymer different from the intermediate segment and has a durometer of no more than about 35D and a length of at least 5 cm. The tip segment has a tapered portion that tapers distally from a first outer diameter to a second outer diameter over a length of between 1 and 3 cm.

Described are methods, systems, devices for facilitation of intraluminal medical procedures within the neurovasculature. A catheter advancement device includes a flexible elongate body having a proximal end, a distal end, and a single lumen extending therebetween. The flexible elongate body has a proximal segment, an intermediate segment, and a tip segment. The proximal segment includes a hypotube coated with a polymer. The intermediate segment includes an unreinforced polymer having a durometer of no more than 72D. The tip segment is formed of a polymer different from the intermediate segment and has a durometer of no more than about 35D and a length of at least 5 cm. The tip segment has a tapered portion that tapers distally from a first outer diameter to a second outer diameter over a length of between 1 and 3 cm.

Inflatable medical devices and methods for making and using the same are disclosed. The devices can be medical invasive balloons, such as those used for transcutaneous heart valve implantation, such as balloons used for transcatheter aortic-valve implantation. The balloons can have high strength, fiber-reinforced walls.

Devices, systems, and methods for catheterization through angionavigation, cardionavigation, or brain navigation to diagnose or treat diseased areas through direct imaging using tracking, such as radiofrequency, infrared, or ultrasound tracking, of the catheter through the patient's vascular anatomy. A steerable catheter with six degrees of freedom having at least a camera and fiber optic bundle, and one or more active or passive electromagnetic tracking sensors located on the catheter is guided through the vascular system under direct imaging. The direct imaging can be assisted with at least one of MRA imaging, CT angiography imaging, or 3DRA imaging as the roadmap acquired prior to or during 3D stereoangiovision. The system comprises RF transceivers to provide positioning information from the sensors, a processor executing navigation software to fuse the tracking information from the tracking sensors with the imaging roadmap, and a display to display the location of the catheter on the roadmap.

A medical device includes an elongated medical device body; a first operating line and a second operating line inserted in an axial direction of the medical device body; and a bending operating part for performing a bending operation of a distal end part of the medical device body by pulling the first and second operating lines, at an intermediate part and a proximal end part in the axial direction of the medical device body, the first and second operating lines extending in parallel so as to be spaced apart from each other in a circumferential direction of the medical device body, and at the distal end part in the axial direction of the medical device body, the first and second operating lines being curved and joined together so as to approach each other in the circumferential direction of the medical device body gradually toward a distal end side.

A catheter insertion device includes a housing, a needle, a guide wire, and a catheter disposed coaxially over the needle. The needle has a proximal end in the housing and a distal end extending from a distal end of the housing in an insertion position. The guide wire has a distal portion disposed in a lumen of the needle in a withdrawn position. The guide wire may include a safety tip having a non-coiled configuration in the withdrawn position and a coiled configuration in an advanced position. The catheter insertion device may include a sliding member attached to the guide wire, wherein movement of the sliding member translates the guide wire from the withdrawn position to the advanced position.