Transfer sets with filters, including transfer sets with filters for peritoneal dialysis (PD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, a transfer set includes a first connector configured to be coupled to a disposable set of a PD system, a second connector configured to be coupled to a catheter of the PD system, and a fluid channel extending between the first connector and the second connector. The transfer set further includes a filter positioned within the fluid channel and configured to filter contaminants from solution flowing within the fluid channel between the first connector and the second connector. In some embodiments, the transfer set further includes a one-way valve positioned between the filter and the second connector and configured to prevent fluid from flowing through the one-way valve in a direction toward the filter.

A tube coupling system serves for providing annular flow through a flexible annular double lumen tube between fluid reservoir(s) and flexible connection pieces of an annular double lumen device. The tube coupling system has a first coupling component and a second coupling component and an end fitting system. The first coupling component that has a female coupling part and a male coupling part adapted for coupling to a proximal end of the flexible annular double lumen tube. The second coupling component has a second interior pipe that axially extends inside a second exterior pipe, a first end fitting adapted for coupling to at least the female coupling part of the first coupling component, and a second end fitting adapted for coupling to any of the flexible annular double lumen tube or the flexible connection pieces of an annular double lumen device.

A percutaneous fluid access apparatus includes a percutaneous fluid access device. The percutaneous fluid access device has a base portion including a subcutaneous portion and at least one port for connection to one or more fluid conduits within a body of a patient. A housing has at least one fluid channel and at least one seal for sealing the at least one fluid channel, and the housing is removably attachable to the base portion. The at least one fluid channel is in fluid communication with the at least one port when the housing is attached to the base portion.

Medical tubing has at least one layer having a composition prepared from a melt blend of (i) a thermoplastic material, (ii) a filler and (iii) a heat reactive coupling agent. The medical tubing can have a kink resistance no worse than a medical tube composed of polyvinyl chloride with the same tubing wall dimensions. The medical tubing can be multilayer and can include single lumen and multi-lumen tubing.

An infusion system and method for providing different medical fluids to a patient. The infusion system, which can be used in complex infusion therapies, includes a catheter with a catheter tube and at least one lumen extending longitudinally through the catheter tube between a proximal tube end and a distal tube end. A plurality of pump devices are each connected to the at least one lumen so as to convey fluid. A control device is connected to the pump devices and adapted to control the pump devices so that the different medical fluids can be delivered through the at least one lumen by the pump devices in time division multiplex. The catheter can include the pump devices. Each pump device can be configured as a micropump mounted at the proximal tube end.

A dual-chamber syringe may include an end wall and a primary plunger. The primary plunger may include a primary stopper. The primary stopper may form a primary chamber with the end wall. A secondary plunger may be in mechanical association with the primary plunger. The secondary plunger may include a secondary stopper. The secondary stopper may form a secondary chamber with the primary stopper. A primary nozzle may extend from the end wall and may be in fluid communication with the primary chamber. A secondary nozzle may extend from the end wall and may be in fluid communication with the secondary chamber.

A negative pressure wound therapy device that includes a first tubing connectable in flow communication with a source of negative pressure configured for application of negative pressure to a wound site, a second tubing in flow communication with the wound site, and a valve.

A delivery device is provided for introducing a fluid to a patient. The delivery device has a base with a bottom face for attaching to the skin of the patient, and a cannula extending from the bottom face for penetrating the skin of the patient. A fluid supply conduit has a first lumen connected to the cannula for supplying the fluid to the cannula, where the fluid contains an active agent and stabilizing agent. The conduit has a second lumen with an open end for capturing leakage of the fluid from the infusion site and carrying the fluid away from the infusion site. The second lumen has a leak detector containing a color changing in an amount to react with the stabilizing agent and produce a visual indication to the patient through the conduit. The leak detector is spaced from the infusion site and oriented in a location visible by the patient through the conduit.

A negative pressure wound therapy device that includes a first tubing connectable in flow communication with a source of negative pressure configured for application of negative pressure to a wound site, a second tubing in flow communication with the wound site, and a valve.

An apparatus including tubing sets, a modular constraint assembly, and methods of use are described for deliver a therapeutic medication to a patient, the apparatus can have a controller and a sensor. The controller is configured to receive data from the sensor, and to start and stop delivery of the therapeutic medication to the patient in response to data received from the sensor. In addition, apparatus, systems and methods are disclosed, which are configured to deliver a therapeutic medication to a patient. The apparatus, system and methods use a reservoir, a patient interface, a tubing set, a modular constraint assembly connected to the tubing sets, and a fluid pump, and the components are configured to provide a calibrated flow rate based upon specific characteristics of the therapeutic medications passing through and internal lumen of the tubing set.