A method, device, or system for treating eye disorders or conditions, comprising restoring or increasing blood flow or blood flow rate in an artery that supplies blood to or in the eye, thereby increasing the amount of nutrient(s) that reaches the eye or a portion thereof. The invention also includes methods, devices, or systems for treating eye disorders or conditions which use reverse flow or retrograde flow structures and systems during the treatment of the eye disease.

A method, device, or system for treating eye disorders or conditions, comprising restoring or increasing blood flow or blood flow rate in an artery that supplies blood to or in the eye, thereby increasing the amount of nutrient(s) that reaches the eye or a portion thereof. The invention also includes methods, devices, or systems for treating eye disorders or conditions which use reverse flow or retrograde flow structures and systems during the treatment of the eye disease.

An artificial chamber including a first conduit, a second conduit, a third conduit, and a wall defining a space; in which the first conduit and the second conduit are positioned opposite one another; in which the third conduit is opposite the wall; and in which the wall has a concave surface is disclosed. The chamber can be part of a system for providing pulmonary support. The system includes the chamber and a first pump connected to the third conduit, and connected to a fourth conduit; in which the chamber receives fluid via the first conduit and the second conduit, in which the first pump receives fluid from the chamber via the third conduit; and in which the fourth conduit transports fluid from the first pump to a first blood vessel. Methods of making a chamber and a system, and methods of using the chamber and system are also disclosed.

A method, device, or system for treating eye disorders or conditions, comprising restoring or increasing blood flow or blood flow rate in an artery that supplies blood to or in the eye, thereby increasing the amount of nutrient(s) that reaches the eye or a portion thereof. The invention also includes methods, devices, or systems for treating eye disorders or conditions which use reverse flow or retrograde flow structures and systems during the treatment of the eye disease.

Some embodiments disclosed herein relate to devices and methods for controlling placement of intraocular implants within a patient's eye including but not limited to placement within or near the collector ducts of Schlemm's canal located behind the trabecular meshwork. In some embodiments, a handheld peristaltic rotor device having a compression element can be positioned on a corneal surface of the eye and rotated to create a peristaltic movement of blood in one or more episcleral veins to generate blood reflux within Schlemm's canal such that one or more collector ducts, or channels, of Schlemm's canal can be located. In some embodiments, an implant can be implanted near the identified location of the one or more collector ducts, or channels.

Some embodiments disclosed herein relate to devices and methods for controlling placement of intraocular implants within a patient's eye including but not limited to placement within or near the collector ducts of Schlemm's canal located behind the trabecular meshwork. In some embodiments, a handheld peristaltic rotor device having a compression element can be positioned on a corneal surface of the eye and rotated to create a peristaltic movement of blood in one or more episcleral veins to generate blood reflux within Schlemm's canal such that one or more collector ducts, or channels, of Schlemm's canal can be located. In some embodiments, an implant can be implanted near the identified location of the one or more collector ducts, or channels.

Extracorporeal circuit devices that can be used for on-pump open-heart surgery to support surgical procedures such as coronary artery bypass grafting are described. In some embodiments, an oxygenator can include an integral pump. Such an integrated arrangement can advantageously provide an extracorporeal circuit with a lower overall volume than other conventional extracorporeal circuits.

The device (300) for use in total cavopulmonary connection comprises a hollow body (302), embedded within the cavity of which is a flow separator (308). The hollow body (302) comprises a first end (304) that is configured to receive blood from inferior vena cava (IVC) and a second end (306) configured to be connected to pulmonary artery. Further, the flow separator (308) aids in guiding blood from IVC and superior vena cava (SVC) to right pulmonary artery and left pulmonary artery. The flow separator (308) comprises an inferior end (402) and a superior end (404). The inferior end (402) is located between the first end (304) and the second end (306) of the hollow body (302). The flow separator (308) is dimensioned to have the superior end (404) enter SVC when the second end (306) is connected to the pulmonary artery.

The device (300) for use in total cavopulmonary connection comprises a hollow body (302), embedded within the cavity of which is a flow separator (308). The hollow body (302) comprises a first end (304) that is configured to receive blood from inferior vena cava (IVC) and a second end (306) configured to be connected to pulmonary artery. Further, the flow separator (308) aids in guiding blood from IVC and superior vena cava (SVC) to right pulmonary artery and left pulmonary artery. The flow separator (308) comprises an inferior end (402) and a superior end (404). The inferior end (402) is located between the first end (304) and the second end (306) of the hollow body (302). The flow separator (308) is dimensioned to have the superior end (404) enter SVC when the second end (306) is connected to the pulmonary artery.

A surgical kit for repairing an aortic aneurysm comprising a vascular prosthesis with a primary conduit forming a primary lumen extending from a primary inlet opening to a primary outlet opening, and a perfusion branch conduit forming a perfusion branch lumen extending from a perfusion branch opening in the primary conduit to a perfusion outlet opening at a distal end of the perfusion branch conduit; and a perfusion apparatus comprising an inlet conduit having a proximal end configured to be fluidly coupled to the distal end of the perfusion branch conduit, a plurality of secondary conduits branching from the inlet conduit and configured for fluid coupling to aortic branches, and a valve assembly configured to selectably alter the plurality of secondary conduits between an open flow state and a closed sealed state.