An implantable circulatory support system, configured to connect a ventricular chamber of a heart, including a valveless displacement blood pump, a deformable polymeric flow cannula, a pair of male and female fasteners, a coupler, a driveline assembly, and a co-pulsatile driver. Forward and backward flow communication between the blood pump and the heart chamber is accomplished using the present flow cannula invention which is anastomosed to the heart chamber in a sutureless manner. When providing circulatory support, the co-pulsatile driver ejects blood out of the blood pump during systolic ventricular contraction and fills the blood pump with blood during diastolic ventricular relaxation.

A blood purification apparatus including the following: a peristaltic pump that includes a stator to which a pump tube including a first portion and a second portion is detachably attached, and a rotor including a roller and a guide portion, the roller delivering liquid by squeezing the pump tube attached to the stator, the guide portion retaining the pump tube at an appropriate position where the pump tube is squeezable with the roller, the rotor being rotatable about a predetermined axis; an anchor member that anchors an attaching member to which the pump tube is attached; and a displacing portion that displaces the attaching member between a set position and an unset position by moving the anchor member with the attaching member being anchored by the anchor member. An attachable state in which the first portion of the pump tube rests at the appropriate position is established when the anchor member is moved from the unset position to the set position with the guide portion of the peristaltic pump being stopped in a specific phase.

A blood pumping device is described having at least a first pump and a first pump actuator for inducing a blood flow in a body's circulatory system. The pump has one upper chamber having an inlet channel and one lower chamber having an outlet channel. The upper and lower chambers are separated by a movable valve plane provided with a one-way valve. The pump actuator induces movement of the valve plane in an upward and downward direction between the upper and lower chambers in response to control signals from a control unit. When the valve plane moves in an upward direction, the valve opens allowing a flow of blood from the upper to the lower chamber. The lower chamber is provided with a bag-like portion forcing said flow of blood to make a turn of between 110° to 150° before leaving through the outlet channel.

An intra-ventricular pulsatile assist system is provided including an intra-ventricular blood pump including a chamber having a distal portion and a proximal portion opposite the distal portion, the proximal portion and the distal portion defining an axis extending therebetween and the distal portion defining an outlet; a valve at the distal portion of the chamber, the valve including a closed position in which the outlet is sealed and an open position in which the outlet is unsealed; and a control circuit including a processor in communication with the blood pump, the processor having processing circuitry configured to determine a pressure value in the chamber and transition the valve between the closed position and the open position when the pressure value in the chamber deviates from a predetermined threshold value.

Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures.

A tube pump having a housing in which a large diameter flexible tube is arranged along a lateral wall formed to have a substantially horseshoe shape, and a roller that moves along the lateral wall of the housing. Between a blockage section which pressures and blocks the large diameter tube and a separation section shaped so as to gradually extend away from the rotation center, the lateral wall is provided with a pressure release section having an arc with a radius larger than the blockage section. While the roller is moving through the pressure release section, a communication opening is formed in the large diameter tube pressured by the roller so as to allow communication between a part positioned on an upstream side and a part positioned on a downstream side of the roller, while a size of the communication opening is maintained to be constant.

A displacement sensing device is configured for a peritoneal dialysis system. The peritoneal dialysis system includes a housing and a syringe. The syringe is disposed on the housing and has a push rod. The displacement sensing device includes a guide rod, a probing module, and a resistance scale. The guide rod is coupled to the push rod, and the probing module is disposed in the housing and is fixed at the guide rod. The resistance scale is disposed at a side of the probing module. The probing module is configured to contact the resistance scale to obtain a resistance value of the resistance scale and determine a displacement magnitude of the push rod. In addition, a peritoneal dialysis system is also mentioned.

An apparatus for performing haemodialysis on a patient comprises: first blood transfer means (3) for selectively withdrawing blood from a patient and storing it in a first storage portion (5); second blood transfer means (11) for removing filtered blood from a filtration device (7) and storing it in a second storage portion (13); and a fluid measurement system (51a, 51b) for periodically measuring the respective volumes of blood in the first and second storage portions; adding the volume of blood in the first storage portion to the volume of blood in the second storage portion at that time in order to calculate the total volume of blood within the first and second storage portions at that time; and comparing the total measured volumes of blood within the first and second storage portions measured over a predetermined time interval to calculate the volume of fluid removed from the blood during that predetermined time interval.

The present disclosure provides intravascular ventricular assist devices for insertion into the vasculature of an individual to improve the overall blood flow of the individual. In many embodiments, the intravascular ventricular assist devices described herein provide an individual with an intravascular ventricular assist device that is sized and configured for insertion into an aortic root or pulmonary root such that its reduced size and placement provide the individual with an improved quality of life.

A blood processing system includes a collection line for carrying blood, a blood separation device for separating the blood into first and second fractions, a plasma delivery line for delivering the first blood fraction to an adsorption device, and a peristaltic pump. The adsorption device adsorbs plasma of the first blood fraction. Portions of the collection and plasma delivery lines are positioned in a channel of the peristaltic pump, and the peristaltic pump causes the blood to flow through the collection line at a first flow rate and causes the first blood fraction to flow through the plasma delivery line at a second flow rate that is less than the first flow rate. In some implementations, the collection and plasma delivery lines are tubes having different internal diameters facilitating such differential flow rates. In some implementations, the peristaltic pump is the only pump in the blood processing system.