A system that enables remote adjustment of oxygen flow from an oxygen source includes a gas source device fluidly coupled to a gas source, a remote delivery device with an outlet for providing gas to a user and an inlet fluidly coupled to an outlet of the gas source device, wherein the gas source device has a control system. The control system determines a current control setting of the remote delivery device based on pneumatic feedback from the remote delivery device and modifies a pressure of gas flowing from the gas source device to the remote delivery device based on the current control setting of the remote delivery device, so that a target flow volume of supply gas associated with the current control setting is delivered to the inlet.

A system that enables remote adjustment of oxygen flow from an oxygen source includes a gas source device fluidly coupled to a gas source, a remote delivery device with an outlet for providing gas to a user and an inlet fluidly coupled to an outlet of the gas source device, wherein the gas source device has a control system. The control system determines a current control setting of the remote delivery device based on pneumatic feedback from the remote delivery device and modifies a pressure of gas flowing from the gas source device to the remote delivery device based on the current control setting of the remote delivery device, so that a target flow volume of supply gas associated with the current control setting is delivered to the inlet.

Methods and apparatus provide automated circuit disconnection monitoring such as for a respiratory apparatus or system. Disconnection of a patient circuit, including a patient interface and air delivery circuit, may be detected and a message or alarm activated. In some versions, detecting occurrences of circuit disconnection event(s), such as by a processor, may be based on an instantaneous disconnection parameter as a function of a disconnection setting. The disconnection setting may be determined based on patient circuit type. The instantaneous disconnection parameter may be determined from detected pressure and flow rate, and may be, for example, a conductance value or an impedance value. Disconnection events may be qualified by one or more detected respiratory indicators. In some cases, instantaneous impedance or conductance may be used to assess re-connection of a patient circuit, detection of flow starvation, determine breath shape for triggering and cycling and to detect patient or circuit obstructions.

The present invention relates to a system for real-time determination of a local strain of a lung during artificial ventilation. The system comprises a device for electrical impedance tomography (EIT), which device is configured to capture an electrical impedance distribution along at least one two-dimensional section through a human thorax, and further comprises a device for assigning the captured electrical impedance distribution, which device is configured to divide the captured electrical impedance distribution at different times during the artificial ventilation into a multiplicity of EIT pixels and to assign a specific value of the electrical impedance at a specific time to a specific EIT pixel.

A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient includes a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the respiratory gas is controlled by a microprocessor, a mixing area for mixing a first gas and a second gas in the respiratory gas flow pathway, a humidification area downstream of the mixing area and configured for humidifying respiratory gas in the respiratory gas flow pathway, and a heated delivery conduit for minimizing condensation of humidified respiratory gas.

A device for perfusing a coronary sinus of a subject's heart which may include: a double-lumen catheter including: a first lumen having: a proximal opening, and a distal opening configured to be positioned in a coronary sinus of a subject's heart; and a second lumen parallel to the first lumen, the second lumen having: a proximal opening, and a distal opening being offset from the distal opening of the first lumen towards the proximal opening of the second lumen in a longitudinal direction, the distal opening of the second lumen being configured to be positioned in a right atrium of the subject's heart; and an oxygenator connected to the proximal openings of the first lumen and the second lumen, the oxygenator is configured to oxygenate deoxygenated blood.

A nasal interface uses asymmetrical nasal delivery elements to deliver an asymmetrical flow through the interface to both nares or to either nare, and a mouthpiece may be inserted to maintain a leak, to improve dead space clearance in the upper airways, decrease peak expiratory pressure, reduce noise, increase safety of the therapy for smaller patients and reduce resistance in the interface allowing desired flow rates to be achieved at reduced motor speeds of associated flow generating devices. Different forms of fittings, such as sleeves or inserts can be attached to nasal delivery elements to improve or optimize the therapeutic effects of nasal high flow. It may allow high pressures to be achieved at lower flow rates, reduce noise, improve patient comfort and efficiently clear anatomical dead space.

A nasal interface uses asymmetrical nasal delivery elements to deliver an asymmetrical flow through the interface to both nares or to either nare, and a mouthpiece may be inserted to maintain a leak, to improve dead space clearance in the upper airways, decrease peak expiratory pressure, reduce noise, increase safety of the therapy for smaller patients and reduce resistance in the interface allowing desired flow rates to be achieved at reduced motor speeds of associated flow generating devices. Different forms of fittings, such as sleeves or inserts can be attached to nasal delivery elements to improve or optimize the therapeutic effects of nasal high flow. It may allow high pressures to be achieved at lower flow rates, reduce noise, improve patient comfort and efficiently clear anatomical dead space.

A system for calculating cardiac output (CO) of a patient undergoing veno-arterial extracorporeal oxygenation includes measuring first oxygenated blood flow rate by a pump in the extracorporeal blood oxygenation circuit as introduced into an arterial portion of the patient circulation system and a corresponding arterial oxygen saturation, then changing the pump flow rate, such as decreasing, to produce a corresponding change in arterial oxygen saturation (wherein such change is outside of normal operating variances, operating errors or drift), which change in the arterial oxygen saturation is measured. From the first flow rate and the second flow rate along with the corresponding measured arterial oxygen saturation, the CO of the patient can be calculated, without reliance upon a measure of venous oxygen saturation. Alternatively, the CO of the patient can be calculated, without reliance upon a change in flow rate by changing a gas exchange with the blood in the extracorporeal blood oxygenation circuit to impart corresponding changes in a blood parameter in the arterial portion of the patient circulation system and the blood delivered from the extracorporeal blood oxygenation circuit.

Secretions that have accumulated at or near an airway of a subject as the subject is being mechanically ventilated are removed by suctioning. Before, during, and/or after the removal of the secretions, steps are taken to mitigated the impact of the suctioning used for secretion removal on the subject. As such, the timing of suction used to remove secretions may be influenced or controlled, ventilation of the subject during suction may be adjusted, ventilation of the subject prior to secretion removal may be adjusted to prepare the lungs of the subject for secretion removal, ventilation of the subject subsequent to suction for secretion removal may be adjusted, and/or other techniques for reducing the impact of suctioning for secretion removal on the subject may be implemented.