The ingestible compositions system includes the co-production of orally-ingestible compositions usable as inhalable respiratory agents including delivery apparatus and related methods.

The ingestible compositions system includes the co-production of orally-ingestible compositions usable as inhalable respiratory agents including delivery apparatus and related methods.

A filter sterilization system includes an expiratory filter having filter material that collects pathogens present in the exhaled gas stream from a ventilated patient. A filter sterilizer includes an ultraviolet (UV) light source that is activated by the system to emit light towards the expiratory filter. Additionally, the system includes a ventilator coupled to a patient breathing circuit that provides a gas mixture from a gas source to the ventilated patient and transfers exhaled gases of the ventilated patient to the expiratory filter.

A filter sterilization system includes an expiratory filter having filter material that collects pathogens present in the exhaled gas stream from a ventilated patient. A filter sterilizer includes an ultraviolet (UV) light source that is activated by the system to emit light towards the expiratory filter. Additionally, the system includes a ventilator coupled to a patient breathing circuit that provides a gas mixture from a gas source to the ventilated patient and transfers exhaled gases of the ventilated patient to the expiratory filter.

An inhalation device, assembly or system can include a kit and a pharmaceutical composition. The device can be adapted for administering therapeutic aerosols to pediatric patients, including neonates, infants or toddlers. The device can further include a vibrating mesh aerosol generator that can be insertable into a flow channel of the inhalation device through a lateral opening, and a valved face mask. The device can be connectable to a gas source through which a gas, such as oxygen, can be received into the flow channel at a low flow rate.

Methods are provided for the treatment of RSV infections in young children. More specifically, methods are provided wherein polypeptides that bind F protein of hRSV and that neutralize RSV infection are administered to the lungs of young children at specific dose regimens.

A method for determining gases proportions to obtain an inhalable medical gaseous composition consisting of a first noble gas, a second noble gas, and oxygen, in order to reach a body temperature value, including determining a proportion of first or second noble gas depending on predetermined parameters, such as the body temperature value and an inhalation temperature value, the determining further including determining, for the inhalation temperature value, two body temperature theoretical values for the first and second noble gas modeled by reference regression lines, calculating a difference between both body temperature theoretical values, calculating a difference between body temperature value and any one of the body temperature theoretical values, calculating a ratio representing proportion of first or second noble gas in the inhalable medical gaseous composition.

A method for determining gases proportions to obtain an inhalable medical gaseous composition consisting of a first noble gas, a second noble gas, and oxygen, in order to reach a body temperature value, including determining a proportion of first or second noble gas depending on predetermined parameters, such as the body temperature value and an inhalation temperature value, the determining further including determining, for the inhalation temperature value, two body temperature theoretical values for the first and second noble gas modeled by reference regression lines, calculating a difference between both body temperature theoretical values, calculating a difference between body temperature value and any one of the body temperature theoretical values, calculating a ratio representing proportion of first or second noble gas in the inhalable medical gaseous composition.

A flow sensor comprises a flow restriction disposed within a passage such that a fluid passing through the passage must pass through the flow restriction. The flow sensor also has an upstream pressure sensor coupled to the passage at a point upstream of the flow restriction and configured to measure and provide an upstream pressure of the fluid within the passage, a downstream pressure sensor coupled to the passage at a point downstream of the flow restriction and configured to measure and provide a downstream pressure of the fluid within the passage, and a temperature sensor coupled to the passage and configured to measure and provide a temperature of the fluid within the passage. The flow sensor also includes a flow sensor processor coupled to the upstream and downstream pressure sensors and the temperature sensor and configured to accept measurements therefrom and calculate a compensated flow rate based at least in part on the measured pressures and temperature.

A nozzle apparatus for dispensing an adjustable combination of gas, having a nozzle outlet adjustably combined with a delivery component. The nozzle outlet may have a groove for receiving a roll pin; and an inner lumen comprising a cylindrical shaft having a diameter between 5/1000ths and 20/1000ths of an inch. The delivery component configured to receive air from the nozzle outlet, may have a first circular ambient air hole having a diameter, and a second circular ambient air hole having the same diameter as the first ambient air hole, and a removable plugging device covering the second circular ambient air hole. The delivery component may be adjustable in orientation with respect to the nozzle outlet, and may be adjustable to vary a concentration of therapeutic gas delivered to a patient.