An inhaler article includes a body extending along a longitudinal axis from a mouthpiece end to a distal end, a capsule cavity defined within the body and a tubular element extending from the distal end towards the capsule cavity. The tubular element defines a central passage extending from the distal end towards the capsule cavity. The tubular element includes at least one air inlet allowing air to enter into the central passage. The at least one air inlet extends in a direction that is tangential to the central passage.

A holder for an inhaler article includes a housing comprising a housing cavity for receiving an inhaler article a sleeve configured to retain an inhaler article within the housing cavity. The sleeve includes a sleeve cavity and is movable within the housing cavity along a longitudinal axis of the housing. The sleeve includes a first open end and a second opposing end. The first open end is configured to receive an inhaler article and the second opposing end of the sleeve is configured to allow air to enter the sleeve cavity. The second opposing end of the sleeve is configured to induce a swirl on the air entering the sleeve cavity.

Nasal cannulas are described herein. The nasal cannula (110) includes a cannula housing (112), a reservoir (160), a nebulizer channel (154), and a gas channel (120). The cannula housing includes at least one nasal extension (116) extending from the cannula housing, wherein the at least one nasal extension is configured to be disposed within a patient's nares. The reservoir includes a reservoir volume configured to dispense a medicament. The nebulizer channel is in fluid communication with the reservoir volume and the at least one nasal extension. The gas channel is configured to direct a gas flow toward the at least one nasal extension through the nebulizer channel, drawing a portion of the medicament from the reservoir through the nebulizer channel with the gas flow toward the at least one nasal extension.

The present invention provides a particulate delivery device with an automatic activation mechanism that pierces or cuts a composition capsule when a cap is removed. The cap cannot be replaced once the device is activated for use. The device allows for gas flow through the device from a gas inlet to a gas outlet through a composition receptacle and dispersion chamber to deliver particulate to the airway of a subject.

The present invention provides a particulate delivery device with an automatic activation mechanism that pierces or cuts a composition capsule when a cap is removed. The cap cannot be replaced once the device is activated for use. The device allows for gas flow through the device from a gas inlet to a gas outlet through a composition receptacle and dispersion chamber to deliver particulate to the airway of a subject.

A kit for enabling delivery of an active compound to the skin for penetration into the skin, a delivery device for delivering an active compound, and a method of delivery of an active compound are provided. An active compound delivery kit for enabling delivery of an active compound into the skin of a subject includes an arrangement for providing a pathway into a biological barrier of a subject in an application zone, an active compound provided in dry form, and a delivery device for delivery of dissolved active compound to the application zone. Provision of a pathway into the biological barrier, preferably skin, is provided and the active compound applied in optimum form within a short time frame after forming the pathway ensuring treatment of the desired skin cells is optimised.

The present invention provides an automatic drug delivery device. The automatic drug delivery device includes an enclosure and a first piston disposed in the enclosure. The first piston partitions the enclosure to a first drug delivery chamber and a first expansion chamber. A first through hole and a second through hole are formed in the wall of the enclosure, the first through-hole communicates with the first drug delivery chamber, and the second through-hole communicates with the first expansion chamber. A first targeted dissolution membrane covers the first through hole and the second through hole, and dissolves at a first targeted region. A drug is filled in the first drug delivery chamber, and an expandable material is included in the first expansion chamber. The expandable material in the first expansion chamber can expand after absorbing liquid.

The present invention relates to an aerosol-generating device (1) for generating an aerosol by dispersing an aerosol-forming powder (31) into an airflow. The device comprises a device housing (2) which comprises an airflow passage therethrough and which is configured to receive a capsule (30) that contains the aerosol-forming powder to be discharged into the airflow passage. The device further comprises a magnetic actuator (40) which is configured to generate a movement of the capsule when being received in the device housing for de-agglomerating the aerosol-forming powder within the capsule. The invention further relates to an aerosol-generating system comprising an aerosol-generating device according to the invention and an aerosol-forming powder containing capsule for use with the aerosol-generating device.

A nasal delivery device for a powder, having a reservoir, a delivery head and an air discharge system generating a flow of compressed air. The air discharge system has an air chamber, formed by a hollow axial cylinder, and a piston that sealingly slides in the air chamber to compress the air. The hollow axial cylinder has a radial shoulder connecting a first cylinder portion and a second cylinder portion. Before actuation, the piston is at the first cylinder portions and, during actuation, the piston sealingly cooperates with the second cylinder portion. The radial shoulder defines a profile that the piston overcomes at start of actuation. The piston has an upper lip and a lower lip, a skirt around the hollow axial cylinder with a lower flange projecting radially inward. The skirt has a profile radially projecting towards the inside, cooperating before actuation with the lower lip of the piston.

A nasal composition is provided comprising or consisting of a first composition part in the form of a liquid for nasal application to a patient in use, and a second composition part in the form of a powder for nasal application to the patient in use. The first and second composition parts are applied to the patient separately or together as required.