A device is described for delivering a therapeutic vibration to a body. The device may include at least two motors in a housing with unbalanced masses coupled to their axles, such that vibration of the masses causes the two motors and housing to vibrate at a beat frequency 80. The motors and housing may be coupled to the body via a platform which places the motors and housings at or near a resonant structure in the body, creating a coupled oscillation between the platform and the body. The vibration may be based on the input signal, such that the system applies the vibration based on the input signal to the user, wherein the signal may be an audio or video signal. The system may be configured to measure and manipulate the flow of cerebral spinal fluid.

Non-enzymatic method and milling device for preparing therapeutic cells from adipose tissue including continuously feeding the adipose tissue to the milling device; mechanically separating the cells or cell aggregates from adipose tissue moving through the milling device by means of a multiplicity of blades of a rotor, wherein the blades are arranged in a spaced arrangement with respect to the overall direction of flow and the blades are moving about an axis of rotation, wherein the axis of rotation is provided essentially parallel to the overall direction of flow, continuously withdrawing the processed tissue comprising the separated cells from the milling device.

An injection device includes a carrier, a needle, a driver coupled to the needle, the driver being slidable relative to the carrier between a retracted configuration and a deployed configuration, a shuttle configured to move the driver between the retracted configuration and the deployed configuration, and a stop configured to move from a first configuration to a second configuration, wherein the stop is configured to maintain the driver in the deployed configuration, and movement of the stop from the first configuration to the second configuration allows the shuttle to move the driver from the deployed configuration to the retracted configuration.

A cloud-based healthcare diagnostic and treatment platform capable of making non-invasive healthcare diagnostics and treatment recommendations based on data captured from combinations of physical activity and mental activity. In an embodiment, the system and method comprise a healthcare diagnostics and treatment module comprising a HIPPA-compliant security gateway, an AI-assisted healthcare diagnostics module, and an alert and treatments module. The HIPPA-compliant security gateway separates out health-related data from streams of data which may include other data such as game data, provides the health-related data to the AI-assisted healthcare diagnostics module which performs diagnoses of the health-related data using machine learning algorithms, and provides the diagnoses to the alert and treatments module which generates alerts and treatments based on the diagnoses.

An automated system featuring a system controller, an oscillation drive, a linear drive, a rotational drive, a flexible drive shaft, a handpiece, and a disposable cartridge used for the application or removal of tattoos and for use in skin treatment such as needling, skin tightening, aesthetic microneedling, and superficial dermabrasion procedures. A needle cartridge or plurality of blades may be couplable in modular configurations within the disposable cartridge. The automated system may also have a plurality of blades or needle bundles in various configurations couplable to the disposable cartridge selected in accordance to the skin treatment performed. The system may also include a physically integrated and functionally automated fluid pump with associated disposable fluid container and disposable feed tube. Alternately, the fluid pump may stand physically and functionally independent of the automated system.

Methods and systems are disclosed for creating and using a neural network model to estimate a cardiac parameter of a patient, and using the estimated parameter in providing blood pump support to improve patient cardiac performance and heart health. Particular adaptations include adjusting blood pump parameters and determining whether and how to increase or decrease support, or wean the patient from the blood pump altogether. The model is created based on neural network processing of data from a first patient set and includes measured hemodynamic and pump parameters compared to a cardiac parameter measured in situ, for example the left ventricular volume measured by millar (in animals) or inca (in human) catheter. After development of a model based on the first set of patients, the model is applied to a patient in a second set to estimate the cardiac parameter without use of an additional catheter or direct measurement.

A system for delivering a composition containing a nutritional supplement matrix to a user through the oral mucosa, in which the matrix is held under pressure in a canister that has a nozzle with at least one rotating internal member positioned between the canister outlet and the nozzle outlet, in which the rotating member agitates the composition to increase atomization to aid in absorption.

A peristaltic pump-based apparatus for capturing circulating tumor cells (CTCs) from blood is provided that includes a feedback control architecture that uses models of pump operation and measures of internal pressure fluctuations of the pump (e.g., in the form time-varying and/or position-dependent pressure oscillation data) to adjust pump operating characteristics that smooth pump operation, thereby improving viscosity and consistency of fluid flowing through the pump to a connected microfluidic capture device.

A device for conveying a biological material includes a body including an aperture configured to enable connection with an outside of the body and a chamber configured to store a biological material, a plurality of conveyors accommodated in the body and configured to convey the material, and a driver configured to select one of the plurality of conveyors, align the selected conveyor with the aperture, and move the selected conveyor to the outside of the body through the aperture.

Embodiments of the innovation relate to a ventilator, comprising: a positive displacement pump having a drive motor and configured to output a predetermined volume of inspiratory gas for each rotation of an output shaft of the drive motor; at least one pressure sensor configured to measure inspiratory pressure; and a control unit having a controller comprising a memory and a processor, the control unit disposed in electrical communication with the drive motor and with the at least one pressure sensor. The controller is configured to: receive at least one of an operation signal and a pressure sensor signal, and transmit a drive motor control signal to the drive motor to adjust at least one of a rotational speed of the output shaft and a number of rotations of the output shaft based upon the at least one of the operation signal and the pressure sensor signal.