A drug delivery assembly is provided for delivering a medicament to a patient via a fluid flow path. The assembly includes a main body having a body housing with a body interface and a controller. The assembly also includes a cartridge having a cartridge housing with a cartridge interface configured to be removably associated to the body interface. A drug reservoir positioned within the cartridge housing is configured to contain a medicament and includes an outlet. An adhesive pad is associated with a surface of the cartridge housing and is configured to removably attach to a human body surface. The controller is configured to execute a drug delivery routine in which at least a portion of the medicament in the drug reservoir is delivered to a subject via the outlet and the fluid flow path when the main body is coupled to the cartridge.

A dose unit including at least one isolated bioactive agent applied on a carrier material in thermal contact with an electrically heating element configured to vaporize a pre-determined amount of the agent for pulmonary delivery thereof is provided herein, as well as devices for effecting vaporization and pulmonary delivery of the isolated agent, and methods for preparing the dose unit, controllably releasing the agent therefrom, methods for pulmonary delivery thereof and methods of treatment of medical conditions treatable by pulmonary delivery of the isolated bioactive agent.

Insulin injection syringes are disclosed that include two types of components, namely, durable components that that do not contact the fluid path and can be reused, and disposable or single-use components that contact the fluid path and are not reused. The durable components do not contact the fluid path so that sterility is not affected. Two different syringe components include a reusable outer sleeve containing scale markings for the syringe and a reusable syringe plunger are provided as durable components in embodiments of the present invention. Syringes manufactured according to the present invention can employ one or both of these durable components. Methods for making, using and packaging such syringes are also disclosed.

Some fluid coupling devices described herein are configured for use in fluid systems for purposes of providing a single-use, aseptic disconnection functionality that substantially prevents fluid spillage when being disconnected. In some embodiments, the coupling portions cannot be reconnected to each other after being disconnected from each other.

A needle set includes a needle guard and a winged needle. The needle guard has upper and lower jaws, each of the upper and lower jaws defining a channel and coming together at a hinge. The upper and lower jaws are separated by slots in sides of the needle guard, which slots divide the sides into upper and lower side walls, respectively. The winged needle can be inserted between the upper and lower jaws, with wings of the winged needle passing through the slots. The hinge has an opening and a tube connected to the winged needle passes through the opening.

A system for filling multiple sterile containers includes a filter with an inlet port and multiple outlet ports, the outlet ports being pre-attached to sterile containers by respective filling lines of each container. Each container has an interior and each of the respective filling lines are connected to a respective container interior. The respective filling lines are sealed to the outlet ports and the containers such that the container interiors are isolated from an external environment except the inlet port, via the filter, forming a combined interior volume which is sterile. A container that is connectable to an outlet port the system has a bladder, a first tube and a second tube connected to the bladder, and a sterilizing filter. The container, the first tube and the second tube, and the sterilizing filter are sterile before water is flowed through the sterilizing filter into the bladder.

Single use hydraulic drive devices and single use large volume injectors are described. A method for single use hydraulic drive including releasing a holding device to move a catalyst coated portion of a rod into a reagent filled chamber, generating pressure in the chamber due to at least one of gas creation and thermal expansion from a chemical reaction between the catalyst coated portion and the reagent, hydraulically displacing a movable object in hydraulic communication with the chamber, and stopping further chemical reaction when the pressure exceeds a holding device force threshold to enable the holding device to re-hold a retracted catalyst coated portion of the rod outside of the chamber. The self-regulating pressure in the chamber enables a controlled rate of hydraulic displacement of the movable object.

A dialysis machine (e.g., a peritoneal dialysis (PD) machine) can include a safety feature that is used to isolate individual fluid lines attached to a disposable cassette. The PD machine can include an interface for a disposable cassette, a plurality of safety mechanisms, and a processor. A plurality of fluid lines are connected to the disposable cassette, and each safety mechanism corresponds to a particular fluid line in the plurality of fluid lines. The processor is configured to detect a hazard condition, such as a loss of power to the PD machine or leak in the disposable cassette, and activate one or more safety mechanisms to isolate corresponding fluid lines connected to the disposable cassette. In one embodiment, the safety mechanisms are spring-loaded clamping mechanisms configured to compress a distensible tube connected to the fluid line. In another embodiment, the safety mechanisms include relay solenoids and/or check valves.

The present disclosure relates to a drug delivery device that has a housing and a cap. The drug delivery device also has a lock that prevents the cap being fully replaced on the housing after the cap has been removed.

A surgical gas delivery device includes a filter cartridge interface and a computer controlled control unit configured to control the circulation of surgical gas during endoscopic surgery. The control unit can operate in a plurality of different modes of operation. A tube set for connecting the surgical gas delivery device to one or more end effectors includes a filter cartridge in fluid communication with the tube set. The filter cartridge is seated in the filter cartridge interface of the surgical gas delivery device to communicate surgical gas between the surgical gas delivery device and the one or more end effectors. The surgical gas delivery device includes a reader operatively connected to receive input from a data carrying element of the tube set. The data carrying element, reader, and control unit can launch a specific one of the modes of operation when the filter cartridge is inserted.