A method of treating a patient by implanting a system comprising an infusion device for injecting a substance, at least one reservoir comprising at least one compartment which accommodates and preserves the substance to be injected, and an active cooling device adapted to cool the reservoir and thereby keep the substance within said at least one compartment of the reservoir at a temperature below 37 C. The method comprises the steps of: cutting the skin, dissecting free at least one area within the patient's body, placing the infusion device and the at least one reservoir inside the patient's body along with the cooling device, such that the at least one reservoir is in fluid connection with the infusion device to supply to the infusion device the substance to be injected into the patient's body, and closing at least the skin after implantation of at least parts of the system.

An external intra-pelvic fundus vesicae support disposed at the outer fundus vesicae position and fixing the front end to the pelvic pecten pubis position to lift internal organs. An injection channel is provided inside an external intra-pelvic fundus vesicae support structure, and a screw hole is formed at an input hole, so that the support can be connected to an in-vitro device. According to the external intra-pelvic fundus vesicae support, a tomoscan three-dimensional modeling technology is used to generate a model file which completely conforms to physiological shapes of the pelvic pecten pubis and the outer fundus vesicae and the spatial form of the abdominal cavity of a typical person, and the external intra-pelvic fundus vesicae support of a frame structure and medical material quality is obtained using 3-D printing technologies. Before a surgery is conducted, a virtual reality technology is used to simulate and verify a surgical safety scheme.

The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted jet injection device.

The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted jet injection device.

A device and method for treating high-altitude sickness can include a handheld device, and can deliver a therapeutic amount of nitric oxide to an individual's lungs in order to minimize or treat high-altitude sickness. The device is self-contained and portable, which allows an individual to carry and use the device in high-altitude or other low-oxygen environments.

A lactation system is disclosed. Embodiments include at least one extraction mechanism including a compression mechanism and a collection mechanism, and a controller. The compression mechanism can include a plurality of manipulable members, each operably coupled to an actuator and arrangeable circumferentially about a breast of a user such that each member can be actuated to selectively apply pressure to a region of the breast. The collection mechanism can be removably coupleable to the compression mechanism and can comprise a storage compartment to receive and store milk The controller can be operably coupleable to the actuators to cause the members to move according to a movement pattern which can be configured to stimulate the breast to induce the flow of milk from the breast and modulated based on sensor feedback. A wearable garment with an inner structure can be removably coupled to the extraction mechanism. An outer cover can be arrangeable to conceal the extraction mechanism.

A subject's forehead, and underlying pre-frontal cortex may be cooled by positioning a pre-cooled heat transfer pack on the subject's forehead so that the heat transfer pack is in thermal communication with the subject's forehead, the temperature of the pre-cooled heat transfer pack being below 10 Celsius. Thermal communication between the subject's forehead and the heat transfer pack may be maintained for a period of time sufficient to cool the subject's pre-frontal cortex. Cooling of the pre-frontal cortex may slow the metabolic rate of the subject's pre-frontal cortex and/or induce an onset of sleep for the subject.

A lactation system is disclosed. Embodiments include at least one extraction mechanism including a compression mechanism and a collection mechanism, and a controller. The compression mechanism can include a plurality of manipulable members, each operably coupled to an actuator and arrangeable circumferentially about a breast of a user such that each member can be actuated to selectively apply pressure to a region of the breast. The collection mechanism can be removably coupleable to the compression mechanism and can comprise a storage compartment to receive and store milk The controller can be operably coupleable to the actuators to cause the members to move according to a movement pattern which can be configured to stimulate the breast to induce the flow of milk from the breast and modulated based on sensor feedback. A wearable garment with an inner structure can be removably coupled to the extraction mechanism. An outer cover can be arrangeable to conceal the extraction mechanism.

An at least partly implantable system for injecting a substance into a patient's body. The system comprises at least one flexibly bendable infusion needle with a tip end of each of said at least one infusion needle arranged in at least one first housing for penetrating the first housing's outer wall in at least one penetration area and having the respective other end arranged in at least one second housing, the first and second housings being adapted for implantation inside the patient's body, wherein the at least one second housing is provided for implantation inside the patient's body remote from the at least one first housing and wherein the injection needle is sufficiently long to bridge the distance from the at least one second housing for remote implantation to the at least one first housing and further through the first housing up to the outer wall of the first housing. The system further comprises at least one drive unit adapted for being coupled to the at least one infusion needle and arranged at least for advancing the tip end of the at least one infusion needle so that the at least one infusion needle penetrates with the tip end or ends thereof said at least one first housing's outer wall in said at least one penetration area.

An intra-pelvic fundus vesicae support disposed at the outer fundus vesicae position and fixing the front end to the pelvic pecten pubis position to lift internal organs. An injection channel is provided inside an intra-pelvic fundus vesicae support structure, and a screw hole is formed at an input hole, so that the support can be connected to an in-vitro device. According to the intra-pelvic fundus vesicae support, a tomoscan three-dimensional modeling technology is used to generate a model file which completely conforms to physiological shapes of the pelvic pecten pubis and the outer fundus vesicae and the spatial form of the abdominal cavity of a typical person, and the intra-pelvic fundus vesicae support of a frame structure and medical material quality is obtained using 3-D printing technologies. Before a surgery is conducted, a virtual reality technology is used to simulate and verify a surgical safety scheme.