Wounds dressings, systems, and methods are presented that involve using a patient's body heat to enhance liquid removal from the wound dressing through a high-moisture-vapor-transmission-rate drape. Additional heat sources or devices, such as nano-antennas or electrical heating elements, may be added or used separately to enhance the removal liquid from the wound dressing. Other dressings, systems, and methods are presented herein.

Wounds dressings, systems, and methods are presented that involve using a patient's body heat to enhance liquid removal from the wound dressing through a high-moisture-vapor-transmission-rate drape. Additional heat sources or devices, such as nano-antennas or electrical heating elements, may be added or used separately to enhance the removal liquid from the wound dressing. Other dressings, systems, and methods are presented herein.

An at least partly implantable system for injecting a substance into a patient's body, in particular a penis erection stimulation system, comprises one or more long, flexibly bendable infusion needles, the tip ends of which are disposed within and implanted along with at least one first housing, in particular adjacent the patient's left and right corpora cavernosa. The respective other end or ends of the infusion needles are disposed and implanted along with at least one second housing remote from the first housing. A reservoir and a pump are also implanted inside the patient's body to supply the infusion needle with infusion liquid. A drive unit also adapted for implantation inside the patient's body is arranged for advancing and retracting the infusion needle such that its tip end penetrates the at least one first housing's outer wall in at least one penetration area, more specifically at least in two different penetration areas either simultaneously or in immediate time succession, thereby injecting the substance into the patient's body.

The present invention relates to a method of replenishing a system for injecting a substance into the patient's body, when the system is implanted in the patient's body. The method involves replenishing the implanted reservoir by a replenishing needle penetrating the patient's skin and injecting infusion liquid comprising the substance through the replenishing needle directly or indirectly into the reservoir.

A skin-patch type large volume drug delivery device (1) comprising a heat exchanger (24) to extract thermal energy from the body/skin surface of the user and to supply the extracted thermal energy to increase the temperature of the medicament. Alternatively or in addition, a Peltier element (35) can be used for the same purpose. The device includes a temperature sensor (31) and a controller (16) for varying the flow rate within the heat exchanger as a function of the drug temperature.

A drug delivery apparatus provides autonomous variable rate delivery of a substance. In some embodiments, the delivery apparatus may be programmable. In some embodiments, the delivery apparatus may be disposable. Optionally the rate of delivery may be dependent on a temperature of a component of the apparatus. Optionally, there may be a time delay between activation of the apparatus and delivery power of the substance.

A method of treating a patient by implanting a system comprising an infusion device for injecting a substance, at least one reservoir comprising at least one compartment which accommodates and preserves the substance to be injected, and an active cooling device adapted to cool the reservoir and thereby keep the substance within said at least one compartment of the reservoir at a temperature below 37? C. The method comprises the steps of: cutting the skin, dissecting free at least one area within the patient's body, placing the infusion device and the at least one reservoir inside the patient's body along with the cooling device, such that the at least one reservoir is in fluid connection with the infusion device to supply to the infusion device the substance to be injected into the patient's body, and closing at least the skin after implantation of at least parts of the system.

The present invention relates to a method of treating a patient by an at least partly implantable system for injecting a substance into the patient's body. In the system, there is provided an infusion device for injecting the substance into a part of the body of the patient, the infusion device being adapted for implantation inside the patient's body, at least one reservoir comprising at least one compartment which accommodates and preserves the substance to be injected, the reservoir being adapted for implantation inside the patient's body in fluid connection with the infusion device to supply to the infusion device the substance to be injected into the patient's body, and an active cooling device adapted for implantation inside the patient's body and adapted to cool the reservoir and thereby keep the substance within said at least one compartment of the reservoir at a temperature below 37? C.

The present invention relates to an at least partly implantable system for injecting a substance into a patient's body. The system comprises at least one implantable infusion needle arranged in at least one first housing, the at least one implantable infusion needle having a tip end for injecting a substance into a penetration area of a patient, and at least one drive unit coupled to the at least one implantable infusion needle and arranged for moving the tip end of the at least one infusion needle for varying the penetration site, wherein the at least one drive unit is a drive unit arranged for moving the tip end of the at least one infusion needle using hydraulic force. The system is adapted to use infusion liquid to be injected into the patient's body as hydraulic fluid.

An at least partly implantable system for injecting a substance into a patient's body. The system comprises an infusion device for injecting a substance into a part of the body of the patient, the infusion device being adapted for implantation inside the patient's body. The system further comprises at least one reservoir comprising at least one compartment which accommodates and preserves or is adapted to accommodate and preserve the substance to be injected, the reservoir being adapted for implantation inside the patient's body in fluid connection with the infusion device to supply to the infusion device the substance to be injected into the patient's body. The system further comprises an active cooling device adapted for implantation inside the patient's body and adapted to cool the reservoir and thereby keep the substance within said at least one compartment of the reservoir at a temperature below 37? C.