The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted jet injection device.

A lactation system is disclosed. Embodiments include at least one extraction mechanism including a compression mechanism and a collection mechanism, and a controller. The compression mechanism can include a plurality of manipulable members, each operably coupled to an actuator and arrangeable circumferentially about a breast of a user such that each member can be actuated to selectively apply pressure to a region of the breast. The collection mechanism can be removably coupleable to the compression mechanism and can comprise a storage compartment to receive and store milk The controller can be operably coupleable to the actuators to cause the members to move according to a movement pattern which can be configured to stimulate the breast to induce the flow of milk from the breast and modulated based on sensor feedback. A wearable garment with an inner structure can be removably coupled to the extraction mechanism. An outer cover can be arrangeable to conceal the extraction mechanism.

An at least partly implantable system for injecting a substance into a patient's body, in particular a penis erection stimulation system, comprises one or more long, flexibly bendable infusion needles, the tip ends of which are disposed within and implanted along with at least one first housing, in particular adjacent the patient's left and right corpora cavernosa. The respective other end or ends of the infusion needles are disposed and implanted along with at least one second housing remote from the first housing. A reservoir and a pump are also implanted inside the patient's body to supply the infusion needle with infusion liquid. A drive unit also adapted for implantation inside the patient's body is arranged for advancing and retracting the infusion needle such that its tip end penetrates the at least one first housing's outer wall in at least one penetration area, more specifically at least in two different penetration areas either simultaneously or in immediate time succession, thereby injecting the substance into the patient's body.

A device and method for treating a wound of a patient with negative pressure is provided. The device comprises a pump chamber that has at least one moveable side of the chamber. The moveable side moves between an intake stroke and an exhaust stroke upon application of an electrical potential. Fluid is drawn into the pump chamber during the intake stroke and expelled from the pump chamber during the exhaust stroke. The pump system may have a magnetic or a piezoelectric element that drives the movement of the pump chamber side.

A device and method for treating a wound of a patient with negative pressure is provided. The device comprises a heat-assisted pump system. The pump system can be powered in part by heat derived from the patient. The pump system may be configured to be highly planar, light weight, and portable. The pump system may comprise a Stirling engine or a thermal acoustic engine.

The present invention relates to an at least partly implantable system for injecting a substance into a patient's body. The system comprises at least one implantable infusion needle arranged in at least one first housing, the at least one implantable infusion needle having a tip end for injecting a substance into a penetration area of a patient, and at least one drive unit coupled to the at least one implantable infusion needle and arranged for moving the tip end of the at least one infusion needle for varying the penetration site, wherein the at least one drive unit is a drive unit arranged for moving the tip end of the at least one infusion needle using hydraulic force. The system is adapted to use infusion liquid to be injected into the patient's body as hydraulic fluid.

The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted jet injection device.

An at least partly implantable system for injecting a substance into a patient's body, in particular a penis erection stimulation system, comprises one or more long, flexibly bendable infusion needles, the tip ends of which are disposed within and implanted along with at least one first housing, in particular adjacent the patient's left and right corpora cavernosa. The respective other end or ends of the infusion needles are disposed and implanted along with at least one second housing remote from the first housing. A reservoir and a pump are also implanted inside the patient's body to supply the infusion needle with infusion liquid. A drive unit also adapted for implantation inside the patient's body is arranged for advancing and retracting the infusion needle such that its tip end penetrates the at least one first housing's outer wall in at least one penetration area, more specifically at least in two different penetration areas either simultaneously or in immediate time succession, thereby injecting the substance into the patient's body.

A medical fluid-line arrangement and a medical elastomeric pump having such a fluid-line arrangement. The fluid-line arrangement transfers a medical fluid between a medical elastomeric pump and a patient port. The fluid-line arrangement has a fluid-line channel with an inlet and an outlet. The inlet connects to an outlet of the elastomeric pump, and the outlet connects to the patient port. A throttle element is connected in a fluid-conducting manner to the inlet and outlet of the fluid-line channel. A portion of the fluid-line channel extends through the throttle element. The throttle element causes a narrowing of an active-flow cross section of the fluid-line channel. The throttle element is encapsulated at least partially in a thermally conductive body having a heat-absorption surface that is larger than an outer surface of the throttle element and that is intended to be applied flat to a skin surface of a patient.

A device and method for treating high-altitude sickness can include a handheld device, and can deliver a therapeutic amount of nitric oxide to an individual's lungs in order to minimize or treat high-altitude sickness. The device is self-contained and portable, which allows an individual to carry and use the device in high-altitude or other low-oxygen environments.