Temperature sensors are configured to sense a temperature for the sleeper and transmit temperature readings. A controller is configured to receive temperature readings; and send to a heating subsystem instructions to initiate a warming process that raises a distal temperature of the sleeper more than a proximal temperature of the sleeper. The heating subsystem that may include a heating element that, when engaged, can raise the distal temperature of the sleeper more than the proximal temperature of the sleeper.

The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO.sub.2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO.sub.2-to-NO reactor cartridge and/or a breakthrough of NO.sub.2, and providing an indication of the remaining useful life and/or breakthrough.

An inhalation device defines a receptacle for receiving an aerosol-forming substrate containing at least one vaporizable substance; an atomizer configured to generate an aerosol from the aerosol-forming substrate; a first sensor configured to generate a first signal or first data associated with a presence of at least one chemical substance in the generated aerosol; a second sensor configured to generate a second signal or second data associated with a further characteristic of the generated aerosol or of the aerosol-forming substrate or of the at least one vaporizable substance; and at least one controller configured to separately analyze both the first signal or first data and the second signal or second data to determine first and second analysis results, and configured to determine an operation mode of the inhalation device or to determine whether to alter an operation of the inhalation device based on both the first and second analysis results.

A method of sanitizing at least a portion of a medical device with a sanitization system comprising a base comprising a sanitizing chamber, a sanitizing gas generator, a primary fan or pump, a secondary fan or pump, and a controller. The sanitizing operation comprising generating a sanitizing gas pulse including causing the sanitizing gas generator supplying a sanitizing gas and causing at least one of the primary fan or pump and the secondary fan or pump to operate for a pulse period, and conducting a dwell operation after the pulse period, the dwell operation comprising discontinuing supply of said sanitizing gas and slowing or stopping said primary fan or pump and said secondary fan or pump for a dwell time.

An aerosol delivery device includes a chamber for receiving an article including an aerosolizable material for delivery by the aerosol delivery device, a transmitter, a receiver spaced apart from the transmitter, and a processor. The processor is configured to: cause the transmitter to transmit a first signal to the receiver at least partially through an article in the chamber in use, so that the receiver receives a second signal, wherein the second signal is the first signal altered by interaction with a signal altering component of the article, and determine article data from the second signal. An article includes an aerosolizable material; and a signal altering component. The signal altering component is configured to alter a first signal transmitted at least partially through the article into a second signal indicative of article data.

A disposable, single-dose delivery device for self-administration by a patient of a predefined amount or dose of drug from a reservoir through an outlet of the reservoir includes a device operation lock to prevent a delivery operation of the delivery device as shipped to the patient, an embedded electronic control unit with a wireless receiver for receiving an unlock command or message, and an electromechanical actuator for mechanically unlocking the device operation lock and enabling delivery device operation by the patient. The control unit is configured to activate the actuator instantaneously and unconditionally upon receipt of the unlock command. The unlocking mechanism of the delivery device is adapted to be activated from remote in response to a confirmative message indicative of additional double check by a Health Care Professional HCP or expert system.

Described herein are an interactive apparatus and methods for sensing and measuring real-time characteristic patterns of a subject's use of a dry powder inhalation system. The inhaler device can be used in a wireless communication mode to communicate with a display to assess the subject's usage of the inhalation system concurrently as the inhalation is performed and thus the subject's inhalation can be evaluated as well as the performance of the inhalation system. The system can also detect the identity of the medicament, its dosage, lot, expiration, etc. and the characteristics profile of a dry powder formulation emitted from the inhalation system in use.

Systems, methods and apparatuses for aerosolizing all or substantially all plant matter, medications, flavors, smells, liquid and/or other material to be aerosolizing are disclosed. Embodiments of the invention comprise an aerosolization chamber sealed except for two or more conduits, a first conduit coupled to a source of fully or almost fully oxygenated gas, a heating element capable of heating the aerosolization chamber to a temperature above a combustion temperature, a second conduit configured to transport aerosolized gases and elements out of the chamber and, in one implementation, at least one valve positioned in the second conduit preventing the flow of atmospheric air into the vaporization chamber. In some instances, the first gas substantially clears the vaporization chamber of atmospheric air prior to reaching combustion temperature. A second gas containing oxygen may be intermixed with the vaporization gases and vaporized elements proximal to the combustion chamber.

The operational parameters of a respiratory apparatus can be controlled through the use of a user interface located on a separate or separable mobile computing device. Sensors or features located on the mobile computing apparatus can be used to adjust the operation parameters or therapy of the respiratory apparatus or otherwise improve the compliance of a patient utilizing the respiratory apparatus.

Disclosed is an auto injector for administering a medicament. The auto injector comprising: a housing; a cartridge receiver configured to receive a cartridge assembly comprising a cartridge (700) and a cartridge code (1000) feature, the cartridge containing the medicament; a code sensor configured to read the cartridge code feature; a drive module coupled to move a plunger rod; and a processing unit coupled to the code sensor and the drive module. The processing unit being configured to: receive from the code sensor a code signal indicative of the cartridge code feature; control the drive module to move the plunger rod to a first plunger rod position, the first plunger rod position being based on the code signal; receive a trigger event; control the drive module to move the plunger rod to a second plunger rod position following reception of the trigger event.