A system and method for correcting a volume of fluid delivered by a fluid injector during an injection procedure is described. The method included determining and compensating for a volume factor associated with compliance of the fluid injector system and correcting for the volume by one of over-driving the distance that the drive member travels in a fluid reservoir, under-driving the distance that the drive member travels in the fluid reservoir, or lengthening or shortening a fluid delivery time.

Systems and methods for automatically improving patient-ventilator synchronization, including a method, performed by a ventilator, for automatic synchrony adjustment in medical ventilation. The method may include delivering positive pressure during a first inhalation phase; cycling to a first exhalation phase at an end of the first inhalation phase according to a cycling sensitivity; and at an end of the first exhalation phase, triggering a second inhalation phase. The method may also include during at least one of the first exhalation phase or the second inhalation phase, detecting a cycling-related asynchrony event; in response to the detecting, automatically adjusting the cycling sensitivity without additional user input; delivering positive pressure during the second inhalation phase; and cycling from the second inhalation phase to a second exhalation phase according to the adjusted cycling sensitivity.

A method for determining at least one parameter for vaporization in an inhaler comprising a vaporizer, based upon resistive heating, and an electronic control device is characterized in that the electronic control device is configured to carry out the following initialization procedure—in particular, after a replacement of a vaporizer cartridge in the inhaler: outputting an inhalation request to a user of the inhaler; in the case of a puff taken by the user following the inhalation request, operating the vaporizer with a comparatively to low vaporization capacity P, and recording a time measurement series of an electrical parameter of the vaporizer; determining a transition point ÜP between a region of low vaporization and a region of high vaporization in the recorded time measurement series; determining and storing at least one parameter associated with the initialization procedure.

Provided is an extended use self-contained, wearable medical device. The device is preferably configured with an infusion deployment mechanism for variably inserting and retracting an infusion needle to different depths, or completely retracting the infusion needle from the infusion site and then re-inserting the infusion needle after a predetermined period of time, throughout an infusion cycle for extending the viability of the infusion site. Another embodiment comprises dual needle deployment mechanisms which may also variably insert and retract the infusion needles. A flow sensor is preferably provided for detecting the stoppage of flow through the infusion cannula and signaling the needle deployment mechanism to attempt infusion at a different depth or to deploy a second infusion needle. A re-fillable reservoir assembly is preferably provided for supplying a drug over the extended use of the device. Another embodiment comprises a partially reusable and partially disposable medical device implementing the above features.

To detect air in a fluid delivery line of an infusion system, infusion fluid is pumped through a fluid delivery line adjacent to at least one sensor. A signal is transmitted and received using the at least one sensor into and from the fluid delivery line. The at least one sensor is operated, using at least one processor, at a modified frequency which is different than a resonant frequency of the at least one sensor to reduce an amplitude of an output of the signal transmitted from the at least one sensor to a level which is lower than a saturation level of the analog-to-digital converter to avoid over-saturating the analog-to-digital converter. The signal received by the at least one sensor is converted from analog to digital using an analog-to-digital converter. The at least one processor determines whether air is in the fluid delivery line based on the converted digital signal.

Ventilator enables operator to enter into the microprocessor estimate of a patient's individual characteristic, such as weight, which the microprocessor uses to control delivered tidal volume and other parameters to match the patient. The operator can select one of several ventilator operational modes (intube, mask, CPR). Sensors input data to the microprocessor to maintain parameter optimizations and accuracy. Visual/audible alarms and tools activate when one or more parameters exceed or fail to exceed predetermined values for patient's weight. Manual over-ride is available. The ventilator has a quick start capability in which the operator turns on power, selects the automatic operating mode, enters patient's characteristic, selects control option starting automatic ventilation of proper volumes inhalation/exhalation periods, pressure, and oxy-air mixture.

A vaporization and inhalation apparatus comprising a cartridge container configured to receive a cartridge including a liquid. The apparatus includes a heating element configured to heat the liquid to a point of vaporization to generate a vaporized form of the liquid. The apparatus also includes an outlet port through which the vaporized form of the liquid is inhaled.

An improved system and method of monitoring the operation of a respiratory or surgical humidifier system. A controllable load can be connected across output terminals to a tube heating element to test the operation of a tube heating element supply circuit. A range of tests may be performed by controlling the state of one or more components and monitoring one or more sensors. Tests may be performed either during or not during therapy and either with a gas supply tube connected or not. Transient currents may also be detected and the power supply to a tube heating element can be stopped where transient currents outside a permitted range are detected.

An improved valve leak detection system. The improved valve leak detection system comprises a membrane pump defining a flow path arranged to be opened and closed by at least one valve, a measuring device, a comparator, and a signal generator. The measuring device is configured to determine a conductivity value between two points on the flow path of the membrane pump, one point arranged upstream of the at least one valve and the other point arranged downstream of the at least one valve. The measuring device measures the conductivity value when the at least one valve is closed. The comparator is configured to continuously monitor the conductivity value. The signal generator is arranged to provide an output signal when the conductivity value is indicative of a valve leak condition for a set number of measurements within a set period of time.

Aspects of the present disclosure provide methods, apparatuses, and systems for closed-loop sleep protection and/or sleep regulation. According to an aspect, a biosignal parameter and ambient noise are measured. The biosignal parameter is used to determine sleep condition of a subject. The sleep condition is determined based on one or more of personalized sleep data or historical sleep data collected using a subset of society. Based on the sleep condition, an arousal threshold is determined. Based on the ambient noise and the determined sleep condition, one or more actions are taken to regulate sleep and avoid sleep disruption.