The present invention relates to a medical device for intranasal delivery of a medicament. The medicament may be any type of medicament suitable for nasal administration and delivery in the form of a spray. The present invention ensures that a complete dosage of the medicament is delivered, especially to specific areas in the nasal cavity, such as the rear of the nasal cavity where the SPG is located.

A microchannel (1) having a spiral geometry structured with asymmetrical curls (2) that enables separation of metastasis cancer cells rarely found in blood from the blood cells and enrichment thereof, which forces the particles or the cells to focus quicker and where high-quality particle focusing in a wider flow rate range can be performed.

A novel dry powder inhaler. By providing a plurality of capsule chambers (1a, 1b, 1c, 1d) arranged in parallel in a capsule dry powder inhalation device, a medicine dispenser containing active components of a composite product or their mixture separately is provided. The dry powder inhaler has a simple structure and is convenient to operate. In addition, the parameters of air inlet channels and an air outlet channel can be adjusted by means of each capsule chamber (1a, 1b, 1c, 1d) according to the properties of powder of a medicine or a combination, so as to provide an appropriate particle distribution for each active component.

A valve cassette for a turbine mechanical ventilator includes a plurality of diaphragm check valves, a plate including a plurality of seats configured for receiving said plurality of diaphragm check valves, and at least one connecting element configured for fixing valve cassette to a turbine housing inlet. Each of said plurality of diaphragm check valves includes a flexible membrane and a plug. Each of said plurality of seats includes a bore for receiving said plug and a plurality of openings through which air is configured to flow through the valve cassette.

An oxygenator and method for oxygenating blood. The oxygenator includes a housing, an oxygenation chamber, and elongated gas permeable conduits that extend across the oxygenation chamber. The blood flow enters and contacts with exterior surfaces of the conduits and exits the oxygenator to transfer of oxygen from within the conduits to the blood flow and transfer carbon dioxide from the blood flow into the elongated gas permeable conduits. The housing includes a gas inlet and is configured to distribute a gas flow received through the gas inlet to the elongated gas permeable conduits so as to a first portion of the gas flow flows through a first set of the elongated gas permeable conduits in a first direction and a second portion of the gas flow flows through a second set of the elongated gas permeable conduits in a second direction that is opposite to the first direction.

A filter for medical infusion lines includes a box-like body having an inlet connector and inside which there is arranged a plate-like element on whose one or both opposite faces there are formed respective channels placed in communication with an outlet connector. Filtering hydrophilic membranes separate the channels from at least one interspace placed in communication with the inlet connector. With the outlet connector there is operatively associated an overpressure valve incorporated in the box-like body of the filter.

Provided herein is a method for assisting breathing in a subject, the method including passing a pressurized airflow through a fluidic diverter, wherein the fluidic diverter converts the airflow into pulses of pressurized air that are diverted alternately to provide a first and a second train of pulses of pressurized air; and directing the first and second trains of pulses of pressurized air into a nasal passageway of a subject to assist breathing. Also provided herein is a device for assisting breathing, including an airflow source coupled to a fluidic diverter. The devices and methods provided herein generate positive airway pressure in the form of pulsatile vortex airflow for the treatment of obstructive sleep apnea in a subject, without the need for a sealed interface between the subject and the device.

An ear disimpactor for disimpacting material impacted in an ear canal and against a tympanic membrane, is disclosed. The impacted material comprises cerumen, insects, and other debris. The ear disimpactor comprises a housing, a warm water irrigation unit, and a suction unit. The housing comprises an ear speculum attached to an outer surface of the housing, a motorized auger comprising a drill bit extending from the motorized auger to a tip of the ear speculum, a warm water line extending from the tip of the ear speculum and across a length of the housing, and a suspension suction tube extending from the tip of the speculum and across the length of the housing. The warm water irrigation unit provides warm water to the ear canal through the warm water line and the suction unit sucks out suspension from the ear canal.

A fluid delivery device and system configured to regulate delivery of fluid through a fluid delivery port to a target site within a patient, such as to identify, locate, dilate, etc., an opening in a tissue wall at the target site. A side port is defined in the wall of the fluid delivery device adjacent to but upstream of the fluid delivery port. If the fluid delivery port is partially or fully obstructed by contacting tissue, the side port provides a relief valve reducing the pressure of fluid from the fluid delivery port impacting the contacted tissue. The fluid flow path upstream of and adjacent to the side port may be tapered to create a Venturi effect which may cause entrainment of excess fluid at the target site into the fluid delivery device. Such entrained fluid may be recycled out the fluid delivery port.

Systems and methods for the treatment of a bodily fluid, for example, using a cartridge that may include a cartridge body configured to retain an adsorptive material and an end segment configured to cover a first end of the cartridge body. The end segment may include a circular face comprising an outwardly truncated conical shape and defining an internal conical space, a cylindrical wall joined to a periphery of the circular face, and an inlet configured to provide fluid connection to a source of the bodily fluid. The inlet may be disposed tangential to the circular face at the cylindrical wall so as to direct bodily fluid entering the cartridge into the internal conical space tangentially so as to decelerate the bodily fluid within the internal conical space prior to contact with the adsorptive material disposed within the cartridge body.