An inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, including: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. In some embodiments, a controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.

A tube system for ventilation with an outer tube (1) and with an inner tube (3) arranged non-centrally in the radial direction in the interior of the outer tube (1) is shown and described. The coaxial type tube system may be provided for ventilation and for medical applications. The flow resistance for the gas is minimized by the inner tube (3) being designed such that it is linearly in contact with an inner wall (35) of the outer tube (1).

Disclosed herein is a sprayer which may include, but is not limited to, a main body with a neck an inner cross section area of which gradually decreases; an air blowing module installed for air in the inside of the main body to be discharged to the outside; a liquid medicine container installed at a lower side of the main body and having air holes at a lid of the liquid medicine container; a nozzle cap having a minimum diameter part at an inner intermediate portion and assembled to the neck of the main body; a nozzle a rear end of which is open and connected to an end of a liquid supply pipe; and a rib which is configured to support in such a way that a central axis of the nozzle can position on a central axis of the nozzle.

An apparatus (10) for micronizing an inorganic salt, having a receiving vessel (14) for receiving the salt (46) to be micronized in an interior of the receiving vessel (14); a grinding unit (22) for comminuting the salt (46) to be micronized located in the receiving vessel (14) and for forming micronized salt particles (54); an ascending pipe (24), which is connected fluidically to the receiving vessel (14) and serves to transport the micronized salt particles (54), wherein one end of the ascending pipe (24) has an outlet orifice (38) through which the micronized salt particles (54) can flow out of the apparatus (10); a fan (26) for generating an air stream (40); and a housing (12) with an air outlet (44) and an air duct (42) connecting the fan (26) to the air outlet (44), wherein the air duct (42) is separated by at least one wall from the interior of the receiving vessel (14), such that the air stream (40) generated by the fan (26) does not flow through the interior of the receiving vessel (14), and wherein the air outlet (44) at least partly surrounds the ascending pipe (24) in a region of the outlet orifice (38).

A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. The heat exchanger may be configured to cause blood flow to follow a spiral flow path.

A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.

Some embodiments of the invention relate to an inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, comprising: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. In some embodiments, a controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.

A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. The heat exchanger may be configured to cause blood flow to follow a spiral flow path.

A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.

A respiratory interface apparatus and method for treating a patient requiring continuous positive pressure ventilation is provided. The interface can create a cylindrical stream of air, or vortex, which forms a respiratory seal with the nostrils of the patient for the transmission of pressurized air therethrough. The vortex air seal is created by annular flow nozzles which tangentially direct pressurized air in a cylindrical pattern extending into the nostrils of the patient. A separate, continuous flow of pressurized air is then transmitted through the cylindrical air seal and into the patient's airway. The air seal which is created allows the patient to receive pressurized air without having to wear a tight fitting mask. The inventive interface can include air pressure sensors and/or microprocessors for tailoring therapy to a particular patient, and can be connected to a standard CPAP machine and delivery tubing for respiratory therapy previously requiring an air-tight seal with the patient.