A laparoscopic anti-clogging device suitable for abdominal surgeries whose main function is to overcome the deficiencies caused by the clogging of a suction tool used in suction irrigation. More specifically an improved suction unclogging means used in Laparoscopic Suction Irrigator Systems (LSIS) that is used in the removal of bodily fluids, exudate and or bodily materials from the abdomen of a patient, allowing suction of a high-volume fluid in deep cavities and prevents interrupting fluid flow due to tissues clogging the device, and having the ability of being modified intra-abdominally to then focus all of its vacuum force on the distal opening, thereby facilitating blood clot busting and suction of solidified fluids as well as directed irrigation.

A pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, with or without a cartridge for delivering a dry powder formulation. The inhaler and cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, small organic molecules, peptides and proteins, including, hormones such as insulin and glucagon-like peptide 1 for the treatment of disease and disorders, for example, diseases and disorders, including endocrine disease such as diabetes and/or obesity.

Vaporizer and/or electronic cigarette chargers useful for the recharging of rechargeable vaporizer or electronic cigarette power supplies such as batteries, compatible vaporizers and/or electronic cigarettes, their components, charging contacts, methods of their use and kits containing such chargers are disclosed.

Disclosed herein is an implantable blood pump assembly that includes a housing defining an inlet, an outlet, a flow path extending from the inlet to the outlet, and an internal compartment separated from the flow path. The blood pump assembly further includes a rotor positioned within the flow path and operable to pump blood from the inlet to the outlet, a stator positioned within the internal compartment and operable to drive the rotor, and an inlet conduit connected to the housing inlet and having a downstream end that has a reduced cross-sectional area that produces a localized region of high velocity blood flow. The blood pump assembly further includes at least one pressure sensor positioned between the inlet and the outlet and configured to detect a pressure of blood flowing through the flow path. The pressure sensor is located adjacent the downstream end of the inlet conduit.

There is provided an IV flow regulator including a first part integrated with a flow control slit, the flow control slit being along a fluid path; a second part integrated with a central stem, the central stem including a spiral surface configured to contact the flow control slit, an area of contact defined by the spiral surface and the flow control slit being shaped substantially like an orifice to enable flow along the fluid path; and a dead space chamfer included in the second part at a portion of the fluid path subsequent to the area of contact.

Phyto material tablets, tablet vaporizers, methods and apparatus for forming phyto material tablets. The tablets are formed to increase vaporization efficiency. Tablets can include break regions to facilitate fracturing into multiple pieces for vaporization. The tablets can also include multiple layers of different phyto material mixtures. Compression molds are used to shape the tablets. The compression molds can be provided on a rotational assembly to facilitate rapid manufacturing of multiple tablets. The vaporizers include heating chambers that are configured to increase the surface area of the tablets exposed for vaporization. The heating chambers include compression or fracture members that compress and/or encourage fracturing of the tablets to assist vaporization.

Exemplary embodiments include dry powder inhalers (DPIs) and patient interfaces which improve delivery of aerosols to patients, especially children.

A component for use in an aerosol provision system is disclosed. The component includes a region through which, in use, an aerosol from the aerosol provision system passes, the component being configured to enable selective interaction of the aerosol with a substance locatable in the region.

The device of the present invention includes a dual chamber gas exchanger that is configured for increased flexibility and scalability for many clinical applications. The dual chamber oxygenator can be configured and used in various applications, such as in a heart-lung machine for cardiopulmonary support during cardiothoracic surgery, in an extracorporeal membrane oxygenation (ECMO) circuitry, as a respiratory assist device for patients with lung failure, and the like. The dual chamber gas exchanger features two sweep gas flow paths and two gas exchange membrane bundles enclosed in a housing structure with various blood flow distribution and gas distribution mechanisms. The gas exchanger includes an outer housing, an intermediate housing, two gas exchange fiber bundles, a blood inlet, a blood outlet, two gas inlets, two gas outlets, two gas distribution chambers and an optional heat exchanger.

A pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, with or without a cartridge for delivering a dry powder formulation. The inhaler and cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, small organic molecules, peptides and proteins, including, hormones such as insulin and glucagon-like peptide 1 for the treatment of disease and disorders, for example, diseases and disorders, including endocrine disease such as diabetes and/or obesity.