This disclosure relates to medical fluid cassettes and related systems and methods. In certain aspects, a medical fluid cassette includes a base having a first region and a second region, a first membrane overlying the first region of the base, and a second membrane overlying the second region of the base. The second membrane is configured to rebound away from the base when a force used to press the second membrane toward the base is released.

An airway device includes an outertube and a scope channel partially enclosed by the outertube. An intraluminal space in the outertube, not occupied by the scope channel, provides a passageway for air flow to the patient. An esophageal cuff is disposed distally on the scope channel. When inflated, the esophageal cuff secures the airway device in the proximal esophagus of the patient and helps to prevent gastric reflux by mechanically blocking gastric content from entering into the larynx. An inflatable bladder is attached at an anterior surface of the scope channel between the esophageal cuff and a distal opening of the outertube. When inflated, the bladder forms a tubular ring that pushes against the epiglottis and/or other soft tissue towards a wall of the hypopharynx to produce an unhindered air passage into the patient's trachea.

A combination positive airway pressure (PAP) or continuous positive airway pressure (CPAP) and resuscitation system and related methods. The systems can be well-suited for use in providing CPAP therapy for a neonate or infant patient, with the ability to also provide resuscitation therapy at a peak inspiratory pressure (PIP) as needed or desired without switching to another system or switching the patient interface. The system can include an expiratory pressure device capable of regulating a positive end expiration pressure (PEEP) of the system, which preferably can also induce pressure oscillations relative to a mean PEEP.

A device for monitoring and/or modifying a peritoneal dialysis treatment, including a memory which stores at least one treatment protocol; a control circuitry connected to the memory, wherein said control circuitry generates a report and/or modifies the treatment if an outcome of the treatment is not a desired outcome of the treatment protocol.

Embodiments of a reduced pressure system and methods for operating the system are disclosed. In some embodiments, the system can include one or more processors responsible for various functions associated with various levels of responsiveness, such as interfacing with a user, controlling a vacuum pump, providing network connectivity, etc. The system can present GUI screens for controlling and monitoring its operation. The system can determine and monitor flow of fluid in the system by utilizing one or more of the following: monitoring the speed of a pump motor, monitoring flow of fluid in a portion of a fluid flow path by using a calibrated fluid flow restrictor, and monitoring one or more characteristics of the pressure pulses. The system can provide external connectivity for accomplishing various activities, such as location tracking of the system, compliance monitoring, tracking of operational data, remote selection and adjustment of therapy settings, etc.

Methods and apparatuses for the therapeutic delivery of nicotine for smoking cessation, harm reduction and/or substitution. Furthermore, the devices and methods herein are useful as an alternative, general nicotine delivery system in place of tobacco combustion or high temperature (over 150 degrees C.) products. In addition, the methods and devices herein are useful for the therapeutic delivery of a drug, for reducing the cumulative drug dose and hence its potential toxic side effects, while increasing its neurophysiological and/or physiological effects. Moreover, the devices and methods herein are useful for addiction treatment or reduction. In certain embodiments, the methods are adaptable to a medicament delivery device that determines a sequence of drug doses to be delivered. Dose information may be used to control operation of the device.

A closure for a medical device includes a base having a terminal end for supporting the base in an upright orientation. A connector is mounted on the base for the attachment to the medical device. Automatic, self-righting capabilities of the closure include a curved, substantially bulbous, exterior surface of the base and a center of mass located between the terminal end and a flange. The flange is connected to the base and includes a multi-level peripheral edge extending outwardly from said base at different distances. An included asymmetrical structure of the closure facilitates the automatic, self-righting capabilities thereof.

A portable respirator as described may include an inflatable bag and a respirator body. The inflatable bag may be arranged to provide air to a patient through a face mask or an endotracheal tube in response to compression/retraction actions applied to the inflatable bag. The respirator body may include a first cover portion and a second cover portion arranged to enclose moving components of the portable respirator and define a substantially circular opening for the inflatable bag to be fitted through, a motor, a pair of levers positioned on opposing sides of the substantially circular opening, and a cam mechanically coupled to the motor and arranged to move the pair of levers in response to a rotation action by the motor such that the pair of levers apply the compression/retraction actions to the inflatable bag fitted through the opening.

A process and a signal processing unit (5) approximately detect a respective characteristic heartbeat time {H_Zp[f](x), H_Zp[s](x.sub.1), . . . , H_Zp[s](x.sub.N)} per heartbeat for a sequence of heartbeats of a patient (P). A sensor array (2.1, 2.2) sends at least one sum signal [Sig.sub.Sum(1), Sig.sub.Sum(2)], which results from a superimposition of a cardiogenic signal and of a respiratory signal. A first detector (25.1) calculates a respective first detection result for each characteristic heartbeat time, and a second detector (25.2, . . . ) calculates a second detection result. The first detector (25.1) analyzes a different sum signal and/or applies a different method of analysis than the second detector (25.2, . . . ). The signal processing unit (5) calculates a respective estimation (representation) for each heartbeat time and uses this estimation as the characteristic heartbeat time. The signal processing unit (5) uses a first detection result and a second detection result to calculate the estimation.

The subject matter described herein provides systems and techniques for enhancing a user’s performance. In particular, the physiological characteristics of the user can be altered toward target characteristics to bring about a particular physiological state in the user. Multiple physiological signals of the user may be sensed. Physiological characteristics indicative of a physiological state of the user may be determined. A differential between the physiological characteristics and selected target physiological characteristics may be determined. A selected energy signal associated with a correction action may be communicated to nerves associated with the user’s skin by outputting, using an energy generator, the energy signal toward the skin with one or more different energy types based on the differential. This may allow a particular targeted physiological state to be more rapidly brought about in the user.