The present disclosure discussed a handpiece for trans-canal delivery of a therapeutic substance to the inner ear. The handpiece can be inserted into the middle ear via a surgical tympanotomy approach. The handpiece can enable a controlled injection of a therapeutic substance directly through the round window membrane and into the inner ear. The direct delivery of the therapeutic substance to the inner ear can enable the delivery of a precise amount of therapeutic substance into the inner ear. Because the therapeutic substance is delivery directly to the inner ear the delivery of the therapeutic substance is not subject to limitations on molecule size and inconsistent diffusion rates that are present when therapeutic substances are diffused across the round window membrane.

In one embodiment, a fluid storage device includes a rigid outer housing that defines a septum cavity, a reservoir cavity, and a channel that extends between the two cavities, the outer housing further defining an outlet in fluid communication with the reservoir cavity, a septum provided within the septum cavity, the septum being made of an elastic polymer and facilitating refilling of the fluid storage device, and a thin, collapsible membrane that does not generate significant restoring forces when it is deformed as fluid is drawn from the reservoir cavity and, therefore, does not completely or partially return to its initial non-deformed shape even if the outlet of the device remains open after doses are administered.

A system and method for providing sensory relief from distractibility, inattention, anxiety, fatigue, and/or sensory issues to a user in need. The user can be autistic/neurodiverse, or neurotypical. The system can be configured to obtain user sensory sensitivity data indicating a user's visual, sonic, or interoceptive, sensitivities; determine, using at least the user sensory sensitivity data, sensory thresholds specific to the user and mediation data corresponding to mediations specific to the user; store the sensory thresholds and mediation data; record, using one or more sensors, a sensory input stimulus to the user; compare the sensory input stimulus with the sensory thresholds; in response to comparing the sensory input stimulus with the sensory thresholds, determine, based at least on the mediation data, a mediation to be provided to the user, the mediation configured to provide the user relief from distractibility, inattention, anxiety, fatigue, or sensory issues.

A hearing training device, is provided, including: a wearable device configured for being worn on the head of a user; a playing device arranged on the wearable device; an acupoint stimulation device, served as a physiotherapy device, comprising a plurality of acupoint stimulation mediums arranged on the wearable device, respectively configured for stimulating a plurality of acupoints on the head of the user and related to hearing, and arranged at the positions of the wearable device corresponding to the acupoints respectively; and a control device being in signal connection with the playing device and storing at least one music file, wherein the control device controls the playing device to play the music file, a beat is formed in an audio track of the music file, and the beat decreases with time, and is fixed until the beat is between 10 Hz and 15 Hz.

A method of treatment for mixed carbon dioxide, carbonic acid, saline and optional active additives for treating non-nasal ailments includes delivery of dosage of the treatment at specified flow rates, using a) main housing having a hollow central area containing the dosage; b) a dosage dispenser head located at the distal end of the main housing, and having at least one flow channel for movement of the dosage from the main housing through the dosage dispenser head and to external of the dosage dispenser head; c) a dosage release control component located between the main housing and the dosage dispenser head to permit flow of the dosage through the dosage dispenser head in response to increased pressure against the dosage; and d) a pressure-changing moveable component on the main housing.

A system for facilitating stress-adaptive virtual experience station includes a virtual display system and camera system coupled to a kinematic rig. An array of transducers coupled to the station interact with a user based on a feedback signal, configured for user health treatments, audio effects, or computational imaging techniques.

A plurality of first sensory cues are generated capable of being perceived by a user. Each first sensory cue of the plurality of first sensory cues is dependent on a position of at least one body member of a performer relative to a performance element of a performance object with which an event is performed. The plurality of first sensory cues being effective for stimulating a first processing center of a brain of the user. A plurality of visual sensory cues are generated capable of being displayed to the user on a video display device. The visual sensory cues providing a virtual visual indication to the user of the position of the at least one body member. The visual sensory cues being effective for stimulating the visual processing center of the brain of the user. The visual sensory cues being synchronized with the first sensory cues so that the position of the at least one body member is virtually visually indicated in synchronization with the first sensory cue and so that the visual processing center is stimulated with a visual sensory cue in synchronization with a first sensory cue stimulating the first processing center. The synchronized stimulation of the first processing center and the visual processing center is effective for teaching the user to perform a version of the event.

Embodiments herein relate to ear-wearable systems and devices that can detect and/or take actions to prevent or alleviate stress related conditions such as post-traumatic stress disorder (PTSD) and the like. In an embodiment, an ear-wearable stress therapy system is included having a control circuit, a first sensor package, a microphone, and an electroacoustic transducer, wherein the electroacoustic transducer is in electrical communication with the control circuit. The ear-wearable stress therapy system can be configured to initiate administration of desensitization and reprocessing (DR) therapy to a device wearer. Other embodiments are also included herein.

Embodiments are generally directed to a securable inner drug delivery plug or stopper that is configured to be inserted into, and secured (retained) within, an opening of the inner ear of an recipient. The securable inner drug delivery plug is configured to deliver drugs directly into the inner ear.

Described here are systems and methods for delivering an active agent to target tissues of the ear, nose, or throat using an expandable member having drug crystals layered thereon, and methods for manufacturing such systems. The expandable member can be delivered to the target tissues in a low-profile configuration and expanded to contact and/or dilate surrounding tissue. Expansion of the expandable member transfers the drug crystals to the target tissues, which then act as an in situ depot that enables maintenance of a therapeutic level of an active agent for a desired time period after removal of the expandable member. Multiple expansions of a single expandable member can be employed during treatment. For example, the systems and methods can be useful when it is desired to treat multiple paranasal sinuses with a single expandable member.