Disclosed is a three-cavity flushable fish mouth laryngeal mask airway catheter, including a cover, the cover is provided with a respiratory chamber for communicating with a respiratory tract and a digestive chamber for communicating with a digestive tract; the digestive chamber is provided with a digestive opening for communicating the digestive chamber and the digestive tract; a peripheral wall of the digestive chamber is tapered from an end away from the digestive opening to the digestive opening; an edge of the digestive opening includes a plurality of protrusions; and the plurality of protrusions are configured to be close to each other due to a squeezing force during a process of inserting the three-cavity flushable fish mouth laryngeal mask airway catheter into a throat to narrow the digestive opening.

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

A rectal injection device configured to inject a liquid into the tissues around the internal anal sphincter of a rectum. The rectal injection device comprises: i) an elongated tube having a distal end and a proximal end; ii) a rounded head coupled to the distal end of the elongated tube; iii) a needle extending from the proximal end of the elongated tube into the rounded head, wherein a tip of the needle is aligned with a hole in the rounded head; and iv) an actuator mechanism configured to move the needle to a deployed position in which the tip of the needle extends through the hole and into the anal tissues and to move the needle to a retracted position in which the tip of the needle is withdrawn within the rounded head.

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

A device allowing the creation of an alimentary bolus flow between two stomas, including means forming a pump; first/second sealed connection means capable of connecting the suction opening to an upstream/downstream stoma located on the abdominal wall of a patient; and first and/or second anti-reflux means. The first and/or second anti-reflux means includes a cavity into which the alimentary bolus passes, an inflatable balloon mounted in the cavity and means for inflating the balloon, that make it possible to modify the inflation of the latter, and the balloon is shaped to shift from an open position in which the balloon is partially inflated and has a neck allowing the passage of the alimentary bolus, to a closed position in which the balloon is more inflated than in the open position and in which the balloon is in contact with the wall of the cavity and the neck is sealed as a result of the portion of the wall of the balloon defining the neck being compressed against itself, at least over a portion of the height of the neck.

This disclosure relates to apparatuses and methods for preventing the onset and progression of POI. In one example, a fan-like polyurethane heat-sealed bilayer that surrounds a plurality of wedge-shaped foam strips that join at a collecting foam portion, is subjected to negative pressure provided through silicone tubing which is sealed to the perforated collecting foam portion. Such negative pressure applied for approximately 48 to 72 hours after closure of the abdomen, helps prevent POI which in turn enhances patient recovery, and reduces the length of their hospital stay.

Devices, system and methods for heating pelvic floor tissues are provided. The devices of the present invention can be used to apply heat to pelvic floor tissues such as rectal, vaginal, urethral and/or bladder tissues in order to treat disorders associated with such tissues.

A medical device includes a host structure that has an interior area and one or more propulsion systems linked to the host structure. The host structure and the propulsion systems are configurable into a peripheral boundary of a size adapted to fit in a lumen or cavity of a living organism such as a human being or animal. The medical device includes one or more power supplies in communication with the propulsion systems. The medical device includes a control unit in communication with the propulsion systems and the power supplies. The control unit has a computer process controller configured to control the propulsion systems to move the host structure and the propulsion systems in the lumen so that the host structure and the propulsion systems are self-maneuverable within the lumen.

An ingestible device, includes a storage reservoir configured to store a dispensable substance and a pressurized chamber configured so that, when a restraining force is removed from the pressurized chamber, the dispensable substance exits the ingestible device via openings in the ingestible device.

An opioid overdose rescue device is provided that includes an ingestible capsule. Within the ingestible capsule is a non-refillable drug dispenser comprising an opioid antidote and at least one sensor configured to detect at least one physiological parameter indicative of an opioid overdose. A controller is also contained within the ingestible capsule and is operatively coupled to the drug dispenser and the least one sensor. The controller is configured to receive a signal detected by the least one sensor of the at least one physiological parameter to actuate release of the opioid antidote from the drug dispenser into the intestine of the patient upon a determination that the at least one physiological parameter falls outside a threshold value or range for the at least one physiological parameter indicating that an opioid overdose has been detected.