Disclosed are various embodiments for improved surgical devices and methods of using the same in connection with bariatric and gastroesophageal surgery. The present disclosure includes a lighted bougie device that can include an elongate member and a light source. The light source can be configured to emit near-infrared light. The light source can also be positioned about the bougie such that light emitted from the light source illuminates along a portion of the bougie.

An ink formulation for gastrointestinal tattooing includes water, carbon black, and hyaluronic acid.

A desired elution profile can be identified, and a delivery device designed to effect the desired elution profile, such as by selecting materials for the constituent components of the delivery device, designing a structure of the delivery device and its constituent components, and selecting a content of formulations, to provide for the designed elution profile at particular expected conditions or at particular times or both.

Disclosed is a localized method for treatment of cancer including the steps of providing a drug delivery catheter; navigating the catheter to the bile duct; and delivering a therapeutic agent into the bile duct. According to one aspect of the method, the drug delivery catheter is a multi-occlusion balloon catheter. The multi-occlusion balloon catheter may include at least two balloons. The multi-occlusion balloon catheter may optionally include a pressure transducer between the balloons to optimize delivery technique.

The endoscopy tool and methods of use disclosed herein are used to move gastrointestinal tissue. The endoscopy tool includes an auxiliary gastrointestinal device, or a catheter, having a proximal region and a distal region. The endoscopy tool includes a non-conductive, polymeric loop coupled to and extending distally from the distal end of the gastrointestinal device. The surfaces of the loop are smooth such that the loop can move intestinal tissue without causing lacerations.

A catheter (1) resector balloon (8) used in the treatment of any type of endoluminal-endobronchial tumoral or non-tumoral narrowing and occlusions and endovascular obstructions seen in the hollow tubular organs such as the trachea, esophagus, urinary tract, biliary tract, etc. and vessels, characterized in that, it comprises the following; at least one flexible pad section with pressure and proximity sensor and/or pad section without pressure and proximity sensor which provides soft stopping at the final wall section where the catheter (1) resector balloon (8) is applied in a soft, flexible and shock absorber manner at the tip (2) portion, prevents punctures, tears, bursts or vascular damages occurred in the tissues and vessels formed as a region, undesired complications, provides stopping without giving any damage to its location.

Embodiments of the invention provide swallowable devices, preparations, and methods for delivering drugs and other therapeutic agents within the GI tract. Particular embodiments provide a swallowable device such as a capsule for delivering drugs or other therapeutic agents (TA) into a wall of the GI tract such as the stomach or small intestine. The swallowable device comprises a sensor, a combustible propellant (CP) and a therapeutic agent preparation (TAP) comprising at least one TA. The sensor triggers the CP to ignite and propel the TAP into the wall of the GI tract in response to an external condition or change in external condition. Embodiments of the invention are particularly useful for orally delivering drugs or other TAs which are degraded within the GI tract and require parenteral injection.

Systems and methods related to reconfigurable medical devices are described. In some embodiments, a reconfigurable medical device may include a central core and a plurality of arms. The arms may be rotatably coupled to the central core such that the plurality of arms may rotate outwards away from the central core to selectively reconfigure the reconfigurable device between a retracted configuration and an expanded configuration. In an initial state, the arms may be biased outwards away from the central core into the expanded configuration. When the reconfigurable device is exposed to a temperature greater than a threshold temperature, the arms may be biased towards the central core into the retracted configuration. In some embodiments, a reconfigurable medical device may include therapeutic compound-loaded needles coupled to distal portions of the arms.

Systems and methods for treating a stricture, for example along the biliary and/or pancreatic tract, are disclosed. An example system may include a handle having a base, a first carriage translatable relative to the base, and a second carriage translatable relative to the base. A sheath may be coupled to the first carriage. The system may also include a catheter shaft having a proximal end region and a steerable distal end region. The proximal end region may be coupled to the second carriage. A needle may be releasably coupled to the handle. The needle may be configured to pass through tissue into a position along the biliary and/or pancreatic tract. The system may also include a steering member having a first end coupled to the steerable distal end region of the catheter shaft and a second end disposed adjacent to the handle.

Medical devices and systems for treating a stricture along the biliary and/or pancreatic tract are disclosed. An example medical device may include a guidewire for use along the biliary and/or pancreatic tract. The guidewire may include an elongate core member having a proximal end region and a distal end region. A coil member may be disposed along the distal end region. An actuation member may be coupled to the coil member. The actuation member may be configured to shift the coil member between a first configuration and a compressed configuration. The coil member may be configured to be advanced across a biliary and/or pancreatic stricture when in the compressed configuration. A sleeve may be disposed over the coil member.