Vagal nerve stimulation devices and methods are provided for treating medical conditions, such as conditions associated with insufficient dopamine and/or endogenous opioids in the brain. A device includes one or more electrodes having a contact surface for contacting an outer skin surface of a patient and an energy source coupled to the electrodes. The energy source generates one or more electrical impulses and transmits the electrical impulses to the electrodes and transcutaneously through the outer skin surface of the patient at or near a vagus nerve. The one or more electrical impulses is sufficient to modulate the vagus nerve and release dopamine and/or endogenous opioids in a brain of the patient.

A PEMF device with a permanent magnet assembly with at least one permanent magnet delivers a strong and persistent magnetic field deep into tissue. A coil controller employs pulse width modulation and a phase controller to deliver a series of fast-rise-time current pulses to a coil assembly configured in proximity to the permanent magnet assembly. The current pulses generate magnetic filed flux and induce voltage by enhancing and retracting the deep magnetic field. The device appears to function as an antenna to transmit the coil electromagnetic field into adjacent tissue.

An illustrative system includes a coil configured to be positioned over a wound on a body and held in place on the body by a magnet implanted within the body; and a controller communicatively coupled to the coil, the controller configured to apply therapeutic electromagnetic pulses by way of the coil to the wound. Other systems and methods for providing therapeutic electromagnetic pulses to a recipient are also disclosed.

The present specification discloses a pulsed electromagnetic field system with planar microcoil arrays integrated into clothing. Preferably, each of the planar microcoil arrays has two or more planar microcoils positioned on a substrate that stretches so that the distance between the arrays in a first, unworn configuration and a second, worn configuration is greater than 5% of the distance in the first, unworn configuration. The planar microcoil arrays are connected to a neuromodulation controller and configured to generate an electrical current and transmit that electrical current, in accordance with a particular stimulation protocol, to each of the planar microcoil arrays.

Vagal nerve stimulation devices and methods are provided for treating medical conditions, such as conditions associated with insufficient dopamine and/or endogenous opioids in the brain. A device includes one or more electrodes having a contact surface for contacting an outer skin surface of a patient and an energy source coupled to the electrodes. The energy source generates one or more electrical impulses and transmits the electrical impulses to the electrodes and transcutaneously through the outer skin surface of the patient at or near a vagus nerve. The one or more electrical impulses is sufficient to modulate the vagus nerve and release dopamine and/or endogenous opioids in a brain of the patient.

Method and devices are provided for treating subjects with Transcranial Magnetic Stimulation (TMS). According to some approaches, the methods and devices are configured for the treatment of ongoing seizures. Other approaches relate to the use of TMS as an antiepileptogenic or for use in determining preferential placement of intracranial probes.

A magnetic coil system for the treatment of foot pain which has an electrical pulse generator sequentially connected to three separate magnetic coils that have been placed around that patient's foot. The magnetic coil system consisting of one bottom coil, one coil on top of the foot and a third coil that is situated around the back of the foot and the bottom of the ankle. The three coils being separately and sequentially activated by the electrical pulse generator. The treatment of plantar fasciitis being accomplished by the activation of a series of intense magnetic pulsations using only the bottom coil.

The present disclosure relates to methods for treating diseases or conditions with pulsed electromagnetic field therapy, where the disease or condition treated is one susceptible to modulation of gene expression by pulsed electromagnetic field therapy. The present disclosure generally relates to methods of modulating gene expression and biological regulatory pathways with pulsed electromagnetic field therapy for treating diseases or conditions associated with such gene expression or regulatory pathways that are susceptible to modulation by pulsed electromagnetic therapy, including diseases or conditions associated with inflammation, nerve pain and wound repair.

In certain variations, systems and/or methods for electromagnetic induction therapy are provided. One or more ergonomic or body contoured applicators may be included. The applicators include one or more conductive coils configured to generate an electromagnetic or magnetic field focused on a target nerve, muscle or other body tissues positioned in proximity to the coil. One or more sensors may be utilized to detect stimulation and to provide feedback about the efficacy of the applied electromagnetic induction therapy. A controller may be adjustable to vary a current through a coil to adjust the magnetic field focused upon the target nerve, muscle or other body tissues based on the feedback provide by a sensor or by a patient. In certain systems or methods, pulsed magnetic fields may be intermittently applied to a target nerve, muscle or tissue without causing habituation.

Systems and methods for enhancing muscle function of skeletal muscles in connection with a planned spine surgery intervention in a patient's back are provided. The method includes implanting one or more electrodes in or adjacent to tissue associated with one or more skeletal muscles within a back of a patient, the one or more electrodes in electrical communication with a pulse generator programmed for enhancing muscle function of the one or more skeletal muscles. Electrical stimulation is delivered, according to the programming during a time period associated with the planned spine surgery intervention, from the pulse generator to the tissue associated with the one or more skeletal muscles via the one or more electrodes, thereby improving neuromuscular control system performance of the one or more spine stabilizing muscles in connection with the planned spine surgery intervention to reduce the patient's recovery time associated with the planned spine surgery intervention.