A method and system for treating a subject with a disorder which provides within the subject at least one photoactivatable drug for treatment of the subject, applies initiation energy from at least one source to generate inside the subject a preferential x-ray flux for generation of Cherenkov radiation (CR) light capable of activating at least one photoactivatable drug, and from the CR light, activating inside the subject the at least one photoactivatable drug to thereby treat the disorder.

A method and system for treating a subject with a disorder which provides within the subject at least one photoactivatable drug for treatment of the subject, applies initiation energy from at least one source to generate inside the subject a preferential x-ray flux for generation of Cherenkov radiation (CR) light capable of activating at least one photoactivatable drug, and from the CR light, activating inside the subject the at least one photoactivatable drug to thereby treat the disorder.

Phototherapy systems and methods of phototherapy are described. In an example, the phototherapy system includes a therapeutic light source configured to emit phototherapeutic light towards a subject; and a placebo light source configured to emit placebo light towards the subject. In an embodiment, the light, including the phototherapeutic light and the placebo light, emitted by the phototherapy system is configured to be visually perceived by the subject as continuous light. In an embodiment, the placebo light is a metameric match of the phototherapeutic light. In an embodiment, the method includes emitting the placebo light in a wavelength range and at an intensity configured to be visually perceived by the user as the phototherapeutic light, such as where the placebo light is a metameric match of the phototherapeutic light.

This invention comprises EEG eyeglasses and eyeglass accessories which enable mobile EEG monitoring while being relatively-unobtrusive for use during daily life. An eyeglass accessory device can be a band with EEG sensors which attaches to a person's eyeglasses and loops across the person's forehead, over the person's head, or around the back of the person's head. This band can be transparent. Such a band can also be integrated into smart eyeglasses instead of being an eyeglass accessory.

Systems, methods and computer-readable media are disclosed for providing therapeutic auditory stimulation. Consistent with disclosed embodiments, a system for providing therapeutic auditory stimulation may comprise a diagnostic unit that computes an EEG spectral density of a patient and a heart rate spectral density of a patient and provides values for one or more EEG frequency bands and one or more heart rate frequency bands. The system may also comprise a therapy unit that generates, based on the provided values, one or more stimulation waveforms corresponding to one or more of the EEG frequency bands and provides the stimulation waveforms for therapeutic auditory stimulation. The stimulation waveforms may comprise audible carrier frequencies modulated by signals with frequencies that vary exponentially with time. The EEG frequency bands may comprise the delta, theta, alpha, beta 1, beta 2, and gamma EEG frequency hands.

Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter. LED lighting systems, methods, and devices can switch between a daytime configuration and a night time configuration, wherein the daytime configuration provides unfiltered light and the night time configuration provides filtered light.

Provided is an ultraviolet irradiation device capable of increasing the irradiance at an affected site (target cells) even when ultraviolet light having the same intensity is emitted. This ultraviolet irradiation device is provided with: a device body configured to be capable of emitting ultraviolet light from a light emission unit; an ultraviolet-transparent substrate disposed on the light emission unit; and an elastic member which is disposed on the surface of the substrate facing away from the device body and made of an ultraviolet-transparent material.

Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter. LED lighting systems, methods, and devices can switch between a daytime configuration and a night time configuration, wherein the daytime configuration provides unfiltered light and the night time configuration provides filtered light.

An object of the present invention is to provide a phototherapy device with which a light irradiation region can be accurately positioned on a treatment site. The phototherapy device according to an embodiment of the present disclosure includes a barrel, a light source which is installed inside the barrel and which emits light, a plurality of imaging units for imaging a marking arranged on a body, a deviation amount calculation unit for calculating a deviation amount between a plurality of images of the marking included in a plurality of images captured by the plurality of imaging units, an image combining unit for combining the plurality of images of the marking based on the calculated deviation amount, a target position determination unit for determining a position of a target in the combined image corresponding to an irradiation region of light from the light source, and a display unit for overlaying and displaying an image of a target on the combined image of the marking.

This invention is a wearable neurostimulation device which transmits selected patterns of low-intensity electromagnetic energy into a person's head for therapeutic purposes. This device can include a wearable ring and/or band which at least partially encircles a person's head and has flexible electroconductive prongs and/or teeth which protrude into and/or under the person's hair.