A method for treating a tumor, comprising identifying a tumor as a colon cancer tumor and implanting in the tumor identified as a colon cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 8.4 MBq hour, per centimeter length.

Embodiments of systems, devices, and methods relating to a beam system. An example beam system includes a charged particle source configured to generate a beam of charged particles, a pre-accelerator system configured to accelerate the beam, and an accelerator configured to accelerate the beam from the pre-accelerator system. The pre-accelerator system can cause the beam to converge as it is propagated from the source to an input aperture of the accelerator. The pre-accelerator system can further reduce or eliminate source disturbance or damage caused by backflow traveling from the accelerator toward the source.

According to an aspect of the present disclosure, a beam control device for radiotherapy is provided. The beam control device may include an electron beam generator configured to emit an electron beam for radiotherapy toward a subject in a first direction. The beam control device may further include a first deflection device configured to generate a defocused electron beam by defocusing the electron beam in a second direction, the second direction being different from the first direction.

The disclosure provides systems and methods for adjusting a multi-leaf collimator (MLC). The MLC includes a plurality of cross-layer leaf pairs, each cross-layer leaf pair of the plurality of cross-layer leaf pairs includes a first leaf located in a first layer of leaves and a second leaf opposingly located in a second layer of leaves. For at least one cross-layer leaf pair, an effective cross-layer leaf gap to be formed between the first leaf and the second leaf may be determined; at least one of the first leaf or the second leaf may be caused to move to form the effective cross-layer leaf gap; and an in-layer leaf gap may be caused, based on the effective cross-layer leaf gap, to be formed between the first leaf and an opposing first leaf in the first layer. A size of the in-layer leaf gap may be no less than a threshold.

A remote diagnostic monitoring and control of physical components of a particle accelerator system has a particle emitting system located at a first physical site and includes one or more particle emitting system components to operate the particle emitting system, a particle delivery system located at the first physical site and including one or more particle delivery system components to operate the particle delivery system, a particle system gateway located at the first physical site and operatively coupled to the particle emitting system components and the particle delivery system components by a first network interface, and a diagnostic monitoring system located at a second physical site remote from the first physical site, operatively coupled to the particle system gateway by a second network interface, and operable to monitor one or more first operating states corresponding to one or more of the particle emitting system components and one or more second operating states corresponding to one or more of the particle delivery system components, and a diagnostic control system located at the second physical site, operatively coupled to the particle system gateway by a third network interface, and operable to modify one or more of the first operating states of the one or more particle emitting system components and the second operating states the one or more particle delivery system components.

A medical imaging tool is described, capable of providing in real time 2-D images of the prompt gamma fields released during patient treatment. Owing to its millimetre position accuracy, the instrument is particularly suited for applications where a precise determination of the end-of-range (Bragg peak) of the beam is of paramount importance, as in cancerous and non-cancerous targets for treatment with ion beams and for the treatment of atrial fibrillation. With its unique dual-layer conception in coincidence, the instrument has high rejection ability against false neutron-generated counts, the principal source of background noise for in-beam dose monitoring. It can also provide a coarse measurement of the gamma incidence angle, permitting a correction of the parallax error, main source of dispersion for large area detectors employing collimators.

An object of the present invention is to prevent disappearance of ions supplied to an accelerator. An eccentric trajectory type accelerator 1 includes a laser source 12 and a target 20 that emits ions by being irradiated with a laser beam emitted from the laser source 12. The eccentric trajectory type accelerator 1 includes a container 10 that forms a columnar space therein, an acceleration electrode structure that accelerates ions in a circumferential direction of the columnar space, and a main coil 38 that generates a magnetic field in an axial direction of the columnar space, and accelerates the ions emitted from the target 20. The target 20 is disposed at a position away from a central axis of the columnar space.

Disclosed herein are radiotherapy systems and methods that can display a workflow-oriented graphical user interface(s). In an embodiment, a system comprises a first display in communication with a server, the first display configured to display a first graphical user interface; a second display in communication with the server, the second display configured to display a second graphical user interface, wherein the server is configured to: present the first graphical user interface for displaying on the first display, wherein the first graphical user interface contains one or more pages corresponding to one or more stages of a radiotherapy treatment, wherein the server transitions from a first page of the one or more pages representing a first stage to a second page of the one or more pages representing a second stage responsive to an indication that at least a predetermined portion of tasks associated with the first stage has been satisfied.

The present disclosure relates a multi-leaf collimator. The multi-leaf collimator may include a plurality of leaves. At least two leaves of the plurality of leaves may be movable parallel to each another. For each leaf of at least some of the plurality of leaves, at least one portion of the leaf may have thicknesses varying along a longitudinal direction of the each leaf. The each leaf may have a first end and a second end along the longitudinal direction of the each leaf.

Systems and techniques may be used to estimate a real-time patient state during a radiotherapy treatment using a magnetic resonance linear accelerator (MR-Linac). For example, a method may include generating a dictionary of expanded potential patient measurements and corresponding potential patient states using a preliminary motion model. The method may include training, using a machine learning technique, a correspondence motion model relating an input patient measurement to an output patient state using the dictionary. The method may include estimating, using a processor, the patient state corresponding to a 2D MR image using the correspondence motion model. The method may include directing radiation therapy, using the MR-Linac, to a target according to the patient state.