A moveable support frame for a radiotherapy device, wherein the moveable support frame comprises at least one mass compensation mechanism, wherein the mass compensation mechanism comprises at least one resilient element.

A particle therapy system includes an accelerator 1 which generates a particle beam for extraction, an irradiation apparatus 21 which irradiates the particle beam to an irradiation target 26, a gantry 18 which rotates together with the irradiation apparatus 21, and an MRI apparatus 50 which rotates together with the gantry 18. The MRI apparatus 50 includes a magnetic circuit composed of an iron core 60 and a plurality of coils 61 serving as a magnetic flux source. The iron core 60 includes two oppositely disposed magnetic poles 63A and 63B, and a return yoke 64 for connecting the magnetic poles 63A and 63B. The magnetic poles 63A, 63B have cavities 65A, 65B. The particle beam passing through the cavity 65A is irradiated to the irradiation target 26.

Various approaches for disrupting target tissue for treatment include identifying a target volume of the target tissue; causing disruption of the target tissue in a region corresponding to the target volume so as to increase tissue permeability therein; computationally generating a tissue permeability map of the target volume; and based on the tissue permeability map, computationally evaluating the disruption of the target tissue within the target volume.

A radiation treatment apparatus, comprising a gantry structure comprising a beam member extending between first and second ends of the gantry structure. The radiation treatment apparatus also includes a radiation treatment head movably mounted to the beam member in a manner that allows (i) translation of the radiation treatment head along the beam member between the first and second ends, and (ii) gimballing of the radiation treatment head relative to the beam member, the gimballing comprising pivotable movement in at least one independent pivot direction defined with respect to the beam member. The radiation treatment apparatus also includes a patient couch operative coupled with the radiation treatment head in manner to provide movement of the patient couch relative to the radiation treatment head.

A system plans a radiation therapy treatment of a target volume based on inputs in the form of: a set of candidate beams (B), where each beam defines an arrangement of a therapeutic beam relative to the target volume; a treatment plan (x) for the radiation therapy treatment that uses a subset of the candidate beams (B); an objective function (F) describing a quality of the treatment plan (x); and a feasible region (X) describing requirements on the treatment plan (x) that must be fulfilled. The objective function (F) and/or the feasible region (X) also reflect a first complexity criterion ((x){circumflex over ()}) limiting a first complexity measure ((x)) to be less than or equal to a maximum first complexity ({circumflex over ()}). An optimization step is executed repeatedly; whereby, in each iteration, an updated treatment plan (x) is calculated by optimizing the treatment plan (x) with respect to the objective function (F) and the feasible region (X). Here, if a termination criterion is fulfilled, a set of selected beams (B*) is calculated based on the updated treatment plan (x). The set of selected beams (B*) is a subset of the set of candidate beams (B). Otherwise, the updated treatment plan (x) is set to the treatment plan (x); an updated first complexity criterion ((x){circumflex over ()}) is calculated; the updated first complexity criterion ((x){circumflex over ()}) is set to the first complexity criterion ((x){circumflex over ()}), and another iteration of the optimization step is executed.

The present invention concerns a method for designing a ridge filter for a charged particle accelerator, for depositing with beams of accelerated particles (100.i) specific doses (Dij) into specific locations within a treatment volume (V) of tissue comprising tumoral cells (3t) by single layer pencil beam scanning (PBS), according to a predefined treatment plan (TP), the method comprising the following steps, Defining an array of spots (Si) defining the bases of cylindrical subvolumes (Vi) defining the treatment volume (V); the subvolumes (Vi) are divided into N cells (Cij). The ridge filter is designed comprising the same number of energy degrading units (11.i) as there are spots (Si). Each energy degrading unit (11.i) is formed by N cylindrical degrading subunits (11.ij) of lengths (Lij) and area (Aij). The lengths (Lij) of each degrading subunit (11.ij) are calculated as Lij=Wij/Wu, and Wij=W0?dij, wherein Wij is the desired subunit water equivalent thickness (Wij), Wu is the subunit water equivalent thickness per unit length (Wu), W0 is the maximum beam range and dij is the desired position of the Bragg peak along the irradiation axis (X). The area (Aij) of each degrading subunit (11.ij) is obtained by determining the area boundary (Aij) of the integral at the numerator satisfying the following Equation (1).

[00001]$\begin{array}{cc}\frac{{?}_{\mathrm{ij}}}{{.Math.}_j{?}_{\mathrm{ij}}}=\frac{?{?}_{\mathrm{Aij}}F\left(y,z\right).Math.\mathrm{dy}.Math.\mathrm{dz}}{?{?}_{\mathrm{Abi}}F\left(y,z\right).Math.\mathrm{dy}.Math.\mathrm{dz}},\mathrm{wherein}& \left(1\right)\end{array}$ ?ij/?.sub.j?.sub.ij is the normalized beam weight, F(y,z) is the fluence of the beam, Abi is the base area (Abi) of the degrading unit (11.i).

Various approaches for computationally generating a protocol for treatment of one or more target BBB regions within a tissue region of interest using a source of focused ultrasound include specifying (i) settings of sonication parameters for applying one or more sequence of sonications to the target BBB region using the source of focused ultrasound and (ii) a characteristic of microbubbles selected to be administered into the target BBB region; electronically simulating treatment in accordance with the protocol at least in part by computationally executing the sequence(s) of sonications and computationally administering the microbubbles having the characteristic; and computationally predicting a tissue disruption effect of the target BBB region resulting from the treatment.

Exemplary applicator(s), devices, systems and methods can be provided for delivering high dose rate radiation therapy, e.g., to patients with cervical cancer. For example, an intrauterine channel can be provided for or with such applicator(s), system(s), device(s) and methods. Further, at least a part of the device should be fixable within the uterus, and be configured and sized to be able to easily inserted and/or removed from the uterus, while be able to easily affix the exemplary device, applicator, etc. in the cavity of the uterus, and hold the channel anchored to the uterus, as it is larger from the cervical canal.

Methods, apparatus and systems for detecting collision are provided. In one aspect, a method includes: obtaining a first model by performing modelling based on an exterior shape of a first component in the target system, the first component being a movable component, obtaining a second model by performing modelling based on an exterior shape of a second component in the target system, the second component being different from the first component, determining a spatial position of the first model and a spatial position of the second model according to a movement process of the first component at each of detection timings, and for each of the detection timings, determining whether the first component collides with the second component according to the spatial position of the first model, the spatial position of the second model, and a collision condition.

According to one embodiment, a monitoring apparatus for a rotating gantry comprising: a rotating gantry that supports both an irradiation nozzle configured to radiate a particle beam and a transport unit configured to transport the particle beam to the irradiation nozzle and rotates around a horizontal axis directed in a horizontal direction; a plurality of cables, each of which is connected at one end to the rotating gantry and is connected at another end to a stationary device; a spool that is provided on the rotating gantry and performs winding or unwinding of the plurality of cables; and a monitoring unit that monitors a state of the plurality of cables in the spool.