Various embodiments provide methods and systems for ultrasound treatment of tissue are provided. Accordingly, a method can include locating an implant in a site in a body, directing a medicant to at least one of the implant and the site, directing ultrasound energy to the site, and accelerating healing of the implant and/or native tissue at the site.

Disclosed is a system for enhancing features of a living organism and further communicating the features with an external device. The system includes a flexible printed circuit implanted under the skin of a living organism and a host placed in proximity of the living organism for powering the flexible printed circuit implant wirelessly utilizing alternating charges. The living organism generates biological signals. The host further includes a memory unit connected to a controller for storing media data and operating instructions, a first electrode for emitting alternating charges with variable frequency, a second electrode floats against the ground; and an interface which wirelessly communicates with an external device. The flexible printed circuit includes a third electrode which mirrors said alternating charges received from the first electrode, and an energy convertor for changing the alternating charges to DC power. The flexible printed circuit includes a bi-directional communication unit to communicate signals with a modem for modulating and demodulating the generated modulated alternating frequency, and an analog I/O unit which processes biological signals received from the bi-directional communication unit. An electro-mechanic coupler enhances the biological signals, further the electro-mechanic coupler generates mechanical waves utilizing a fixed structure of said living organism. Further, the coupler converts mechanical waves into electrical signals and furthermore communicates the electrical signals containing processed biological signals with an analog I/O unit, and further the electro-mechanic coupler emits and receives alternating charges. Further, the analog I/O unit processes the electrical signals and communicates the information to the bi-directional communication unit.

Methods and apparatus for optically recognizing tissue parameters during an energy-based tissue-sealing procedure involve grasping tissue with a tissue-sealing instrument, illuminating the grasped tissue or tissue adjacent to the grasped tissue with light, analyzing the light that is transmitted, scattered, or reflected by the tissue, and recognizing the tissue based on the result of analyzing the light. The wavelength of the light may be selected so that a vessel is sufficiently recognizable in tissue containing the vessel. A marker may also be introduced into fluid flowing in the vessel to increase the contrast between the vessel and tissue containing the vessel. Analyzing the light includes analyzing the spatial and spectral distribution of light. Analyzing the light may also include forming the light into an image of the illuminated tissue. The image of the illuminated tissue may be projected onto the eyes of a surgeon or sensed by a matrix of light detectors disposed on a jaw member of the tissue-sealing instrument and transmitted to a display.

Antibiotics are administered in a surgical site subcutaneously via a small or stab incision in the surgical field. Transcutaneous ultrasonic vibrations are applied across the surgical field, which is then opened in the usual manner, to thereby provide a surgical field which contains a vastly higher and more effective level of antibiotic. At the same time the underlying tissue is hydrated.

Disclosed are apparatuses and methods for reducing or limiting bleeding (e.g., blood loss and/or bleeding time) in an animal by trigeminal stimulation. The apparatuses and methods may activate one or more branches of the trigeminal nerve. This activation may be invasive or non-invasive.

Enhancing chondrogenesis at a desired site by the application of ultrasound in the presence of microbbubles. A biomimetic scaffold may be seeded with stem cells capable of undergoing chondrogenesis and provided to the site and then subjected to ultrasound excitation in the presence of microbubbles.

A system for individualized treatment of a tissue condition with acoustic pressure shocks includes personalized determination and automatic adjustment of a shock wave treatment regimen or shock wave dosage to be administered for personalized treatment based on factors such as a patient's comorbidities, state of the tissue condition, individual physical characteristics and lifestyle parameters.

An ultrasonic medical treatment probe has a head with a distal-most circular rim extending along an endless uninterrupted perimeter around a broad recess and formed with a series of serrations or teeth. The rim is thin in comparison to the width of the recess. The serrations or teeth preferably extend continuously along an entire circumference or length of the rim. The probe head is provided along the rim with a plurality of notches or openings communicating with the recess.

The systems and methods in accordance with the principles of the invention can promote correction of an aesthetic or functional defect in a target tissue. A method can include non-invasively applying a cooling agent to a surface of a target tissue; and cooling one or more tissue layers of said target tissue to a predetermined therapeutic temperature, wherein applying the cooling agent is performed such that cryoablation of said one or more layers of the target tissue does not occur. The system can include: a controller and a probe having a distal end configured for non-invasive contact with a surface of a target tissue to cool the target tissue based on treatment parameters.

An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and a means for providing simultaneous aspiration and irrigation of the wound. The apparatus also comprises means to apply high frequency vibrational energy, e.g. ultrasound, to the wound bed. The former removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting wound healing over the wound bed. The latter promotes healing. The dressing and a method of treatment using the apparatus.