Structures and methods for ultrasound treatment of neurological and psychological conditions, using energy levels which do not cause heating or cavitation. The structure includes an outer casing comprising a first material, and a disk positioned inside the outer casing. The disk comprises a second material that differs in composition from the first material and that has a higher acoustic attenuation of ultrasound energy than the first material.

A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.

Disclosed are systems and methods for focusing ultrasound transducers that include multiple separate, independently movable transducer segments.

The present invention relates to an ultrasonic surgical device in which a cartridge comprises: a cartridge housing having an empty inner space filled with a medium; an ultrasonic therapy part which is movably provided inside the cartridge housing and includes a transducer for generating focused ultrasonic waves; a window through which the ultrasonic waves generated from the transducer pass; and a driving part which moves the ultrasonic therapy part inside the cartridge housing, wherein, as the transducer moves in one direction, the distance between the window and the transducer repeatedly increases and decreases.

A device for a soft tissue treatment of a patient. The device includes an applicator including at least one electrode, a fastening mechanism to fix the applicator to a body part of a patient, and a control unit including a microprocessor to control the at least one electrode. The at least one electrode may provide a radiofrequency energy and an electric current. The radiofrequency energy may cause a heating of a soft tissue. The electric current may cause a muscle contraction. The body part includes a face or a chin.

An ultrasound treatment head and an ultrasound imaging and treatment method using the same are disclosed. The ultrasound treatment head according to an embodiment comprises: a structure including a treatment transducer and an imaging probe positioned at the center of the treatment transducer, the treatment transducer and the imaging probe being physically aligned; a first mechanism for steering the mechanical movement of the entire structure; and a second mechanism for steering the mechanical movement of either the imaging probe or the treatment transducer alone in the structure.

An ultrasonic treatment head includes a head body and a cartridge. The head body includes: a body housing for supporting and protecting internal components and providing an interface for a user; a first actuator generating reciprocation on a first axis; a second actuator generating reciprocation on a second axis, and a stage pivoted about a fixed axis by the first actuator and the second actuator. The cartridge includes: a cartridge housing for keeping a transducer and liquid therein; a flat window disposed on the cartridge housing to transmit ultrasonic waves to a treatment area; a body coupler for coupling to the head body; an ultrasonic transducer generating ultrasonic waves in response to an operation signal input through the body coupler; and a fitting assembly moving the ultrasonic transducer on the flat window for in-plane scanning by a pivot motion, which is transmitted through the body coupler, of the stage.

Provided is an ultrasonic treatment apparatus provided with: a treatment-ultrasonic-wave irradiator that irradiates the biological tissue with focused ultrasonic waves, thus heating the vicinity of a focal point of the focused ultrasonic waves at a deep portion of the biological tissue to a temperature that is equal to or greater than a thermal-denaturation temperature of the biological tissue; and a pre-heating-energy irradiator that irradiates the biological tissue with energy waves, thus heating the vicinity of the focal point to a temperature that is less than the thermal-denaturation temperature, wherein the pre-heating-energy irradiator irradiates the biological tissue with the energy waves from a direction different from the direction in which the treatment-ultrasonic-wave irradiator irradiates with the focused ultrasonic waves.

An apparatus is disclosed for thermal therapy in a male prostate patient. The apparatus includes a long tubular element that is to be inserted into a patient's urethra so that a first tip end of it reaches up into the patient's diseased prostate. The elongated portion includes a narrow cylindrical tube within which an ultrasonic array is disposed along the long axis of the cylinder. Fluid is pumped into and out of a treatment zone of said patient as needed to control a temperature of a region in said treatment zone. A motorized driver is used to controllably rotate said elongated portion and the ultrasound array therein about the long axis of the apparatus so as to deliver acoustic energy to said diseased tissue. Various control and monitoring components may be used in conjunction with the present apparatus to design, control, and terminate the therapy.

The present disclosure relates to a chlorin derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, an anti-tumor composition including the chlorin derivative or the pharmaceutically acceptable salt thereof, use of the chlorin derivative or the pharmaceutically acceptable salt thereof in the treatment of a tumor, and a combination of the chlorin derivative or the pharmaceutically acceptable salt thereof and an ultrasound medical system. The chlorin derivative or the pharmaceutically acceptable salt thereof has a structure represented by formula (I), and the ultrasonic medical system comprises a transducer ultrasonic bed and a contact agent. The chlorin derivative of the present disclosure can be used in photodynamic therapy and sonodynamic therapy, thereby effectively inhibiting and treating cancer.