A method for freezing a liquid located in a container, in particular a liquid drug, includes exposing the container to a cooling element such as cold gas in order to freeze the liquid. The cold gas preferably flows around the container, and/or the liquid is cooled in another way in order to freeze the liquid. The container is insulated at a surface of at least one first volume portion of the container, and the container is cooled nearly immediately at a surface of a second volume portion of the container by the cold gas such that the liquid freezes through later in the at least one first volume portion than in the second volume portion.

A dry vapor cryogenic storage container includes an absorbent core made from a porous material that absorbs a liquid cryogen and releases the cryogen in vapor form as the absorbed liquid evaporates. Fluid channels are formed in the absorbent core to increase the available surface area through which the liquid cryogen can be absorbed. The core can absorb the cryogenic liquid much faster with inclusion of the fluid channels. The absorbent core can be made by cutting a cavity and drilling holes in a stack of calcium silicate panels. The cavity holds a contents container or an inner core. The inner core can be part of an extractor and made from porous material including fluid channels for absorbing liquid cryogen. Contents containers can be housed in the inner core.

An automated cryogenic storage system includes a freezer and an automation system to provide automated transfer of samples to and from the freezer. The freezer includes a bearing and a drive shaft though the freezer, the drive shaft being coupled to a rack carrier inside the freezer and adapted to be coupled to a motor. The automation module includes a rack puller that is automatically positioned above an access port of the freezer. The rack puller engages with a sample rack within the freezer, and elevates the rack into an insulating sleeve external to the freezer. From the insulating sleeve, samples can be added to and removed from the sample rack before it is returned to the freezer.

The present disclosure comprises an evaporative cooling assembly (200) for cooling an apparatus (220), and a method for cooling an apparatus (220). The evaporative cooling assembly comprises a refrigerant tank (202), the refrigerant tank (202) containing refrigerant (204). The apparatus also comprises a first evaporator (210) configured to be positioned proximal to the apparatus (220), and a second evaporator (216) positioned to cool the refrigerant tank (202). Each of the first evaporator (210) and the second evaporator (216) are in fluid communication with the refrigerant tank (202), and the second evaporator (216) is positioned downstream of the first evaporator (210). The method for cooling a heated apparatus (220) comprises passing a refrigerant (204) from a refrigerant tank (202) to a first evaporator (210), which is located proximal to the apparatus (220). At least part of the refrigerant is evaporated, and then passed to a second evaporator (216), which is positioned to cool the refrigerant tank (202).

The present disclosure provides cryogenic storage systems and methods of using the cryogenic storage systems. A cryogenic storage system of the present disclosure may comprise a cryogenic tank with an inner door and an outer door, and a robot apparatus located adjacent to the cryogenic tank. The cryogenic tank may store multiple racks such that at most a single rack is removable through the inner door or the outer door. The cryogenic tank may store the multiple racks in multiple groups of racks comprising a first group of racks located at a first radial distance and a second group of racks located at a second radial distance that is greater than the first radial distance. The robot apparatus may selectively open and close the inner or outer doors, and insert or withdraw the single rack into or out of the cryogenic tank through the inner door or the outer door.

The present invention relates to a shipping container for cryopreserved biological samples in which a cryopreserved sample can be maintained on arrival at its destination for a period of time, for example several months.

A cooling system for a cryochamber comprises compressors, heat exchangers and flow restrictions. Compressors are used to pressurize the working fluid, heat exchangers are used to release the heat to the ambient, absorb heat from the interior of the cryochamber to decrease the temperature inside the cryochamber, to cool the working fluid below the ambient temperature using source of cold or to recuperate heat of the cold working fluid stream. Flow restrictions are used to decrease the pressure of the working fluid which results in its temperature decrease. Cryochambers are used for whole-body cryotherapy and require cooling systems that are able to lower the air temperature inside the cryochamber to −90° F.

A railcar backup cooling system may be added to an existing railcar (e.g., a boxcar) to provide supplemental or backup cooling to the railcar in the event that an HVAC failure or other circumstance occurs, which causes the interior temperature of the railcar to rise. The system includes a container of liquid or compressed gas mounted on the railcar, a valve controlling the flow of the liquid or gas from the container, and a controller configured to open the valve when the HVAC system fails or is otherwise unable to maintain the railcar at the desired temperature. When the valve is opened, the liquid and/or gas stored in the container may exit, expanding into a cool gas and thereby acting to cool the railcar environment.

The present invention is to issue a quality certificate on which a graphic image representing the quality in chronological order of a cooling environment in a container accommodating articles therein is printed on a recording medium, upon arrival of the articles at a delivery destination. A delivery unit 15 is mounted on a vehicle 21 and is used to deliver the articles accommodated in a storage container 33 filled with a cooling gas. The delivery unit 15 includes a thermometer Se1 that measures a temperature in the storage container 33, a memory unit 53 that memorizes therein data of the measured temperature in chronological order, a quality-data generation unit 55a that generates quality data of articles based on temperature data acquired from the memory unit 53, a print-data editing unit 55h that edits print data relating to a quality certificate including a graphic image representing the quality in chronological order of the cooling environment in the storage container 33 accommodating articles therein during delivery based on a serial number of the article and the quality data, and a printer 27 that prints print data relating to the quality certificate on a recording medium.

The present invention is to issue a quality certificate on which a graphic image representing the quality in chronological order of a cooling environment in a container accommodating articles therein is printed on a recording medium, upon arrival of the articles at a delivery destination. A delivery unit 15 is mounted on a vehicle 21 and is used to deliver the articles accommodated in a storage container 33 filled with a cooling gas. The delivery unit 15 includes a thermometer Se1 that measures a temperature in the storage container 33, a memory unit 53 that memorizes therein data of the measured temperature in chronological order, a quality-data generation unit 55a that generates quality data of articles based on temperature data acquired from the memory unit 53, a print-data editing unit 55h that edits print data relating to a quality certificate including a graphic image representing the quality in chronological order of the cooling environment in the storage container 33 accommodating articles therein during delivery based on a serial number of the article and the quality data, and a printer 27 that prints print data relating to the quality certificate on a recording medium.